IZiko le-BIOOCUS CGT
Isixeko sezonyango saseTianjin esihlala ixesha elide
Unyango lweSeli, iGene, kunye neTissue (CGT) olukumgangatho weHlabathi lweZigulana zeHlabathi
Njengenxalenye ye Inethiwekhi yezonyango ye-BIOOCUS Global, iTianjin Perennial Medical City imi njenge Iziko eliphambili laseMantla eTshayina le-oncology eyenzelwe umntu ngamnye kunye namayeza okuvuselelaEli ziko lidibanisa unyango oluphambili lwe-CAR-T, TIL, NK cell, kunye neeseli ze-stem, ukukhonza izigulane ezivela ngaphezu Amazwe angama-50 kwihlabathi liphela.
Ukususela ngo-2016, iziko liye lanyanga ngaphezulu Izigulane ze-CAR-T eziyi-1,600(ukusukela ngo-Okthobha 2025), ukufezekisa oku:
● Ukukhululwa kokuqala kwama-80–90%
●40–60% ukuxolelwa ngokupheleleyo kwexesha elide (CR)
● Izinga lokuphendula lilonke eliyi-95%+ (ORR)kwiimhlaza zegazi
● Izinga lokulawula izifo eliyi-60–92% (DCR)kwiithumba eziqinileyo
Ezi ziphumo zixhaswa yi Itekhnoloji ye-CAR-T ephuculweyo ye-IL-15, nto leyo ephucula ukungena kwethumba, ukusinda kweeseli ze-T, kunye nokuchasana nokuphuma kwe-antigen.
Unyango lwe-CGT oluPhambili oluneziphumo zeKliniki eziQinisekisiweyo
Ipotifoliyo yoNyango eBanzi
Unyango lwe-CAR-T
lIithagethi: CD19 / BCMA (hematologic), CLDN18.2 (amathumbu), GPC3 (isibindi/HCC), CEA (lung/NSCLC), B7H3 (glioma), GD2 (neuroblastoma)
lIziphumo: Ukuya kuthi ga kwi-90% ye-CR yomhlaza wegazi kunye nolawulo olubalulekileyo lwezifo kwiintlobo zeethumba eziqinileyo.
Unyango lwe-TIL
lIziphumo: I-40% ye-ORR kunye ne-80% yokunciphisa ithumba kwizigulane ezine-melanoma.
Unyango lwe-NK Cell kunye neStem Cell
lUkubandakanya amayeza e-ADC, ii-organoids ze-tumor, kunye nonyango lwe-radionuclide (Y-90, Lu-177, Ac-225) ukuze kunyangwe ngokuchanekileyo ngokweemfuno zomntu ngamnye.
| Uhlobo lomhlaza | Ithagethi | Izigulane | I-ORR | I-DCR | Iziphumo eziphambili (Idatha ye-BIOOCUS) |
| Umhlaza Wegazi | CD19 / BCMA | ~1,000 | 95%+ | – | 90% CR; 40–60% CR yexesha elide |
| Umhlaza we-GI | CLDN18.2 | 98 | 38.8% | 91.8% | mPFS 4.4m; mOS 8.8m |
| Isibindi (i-HCC) | I-GPC3 | 32 | 56.6% | 86.7% | mPFS 13m; mOS 14.6m |
| Umphunga (i-NSCLC) | I- | 10 | 55.6% | 88.9% | I-OS yonyaka omnye 77.8% |
| I-Glioma (rHGG) | B7H3 | 39 | 30–40% | 60–70% | mOS 11–13.6m |
| I-Melanoma | UKUYA | 12 | 40% | 80% | Ukunciphisa ithumba ngama-80% |
Iprofayili yoKhuseleko:
Uninzi lwezigulane lufumana kuphela i-CRS ethambileyo; akukho bantu bafayo okanye i-ICANSzixelwe kwizifundo eziphambili zeklinikhi.
I-Oncology eNgcono kwiinkalo ezininzi – Unyango oluDibeneyo oluNxibelelanayo oluSimahla neSinye
Isixeko sezonyango saseTianjin esihlala ixesha elide
I-BIOOCUS Tianjin Perennial ibonelela ngeenkonzo ulawulo olupheleleyo, olusekelwe kwiqela lomhlazangokusebenzisa unyango olunezifundo ezininzi (MDT)imodeli, edibanisa utyando, unyango olungenelelayo, unyango lwe-immunotherapy, i-radiology, kunye nonyango oluxhasayo.
AmaSebe aPhambili kunye neeNgcali
Utyando kunye ne-Oncology yoNcedo:Unyango olungena kakhulu (i-nanoknife, i-cryoablation, i-RFA, i-laparoscopy) olukhokelwa yi- UNjingalwazi uLiang Han(umhlaza wesisu) kunye UDkt. Li Liming(umhlaza we-urological).
I-Oncology yezonyango:Unyango olujolise kwi-immuno-target oluphambili phantsi UGqr. Yao Yaqun, kunye namava angaphezu kweminyaka engama-40 kwi-GI, imiphunga, kunye nomhlaza wamabele
Amayeza eNyukliya:Ubume bobugcisa Umfanekiso wePET-CTkwaye unyango lwe-radionuclide ekujoliswe kulo.
Unyango ngemisebe:Ixhotyiswe nge I-TOMO, iGamma Knife, i-VMAT, i-SBRT, kunye ne-ARTiinkqubo; I-BNCT kunye nonyango lweprotoniza kuqaliswa kungekudala.
Ukhathalelo Olupheleleyo:Idibeneyo I-TCM, inkxaso yesondlo, unyango lwengqondo (uGqr. Wang Yulu)kunye utyando lokwakha ngokutsha (uGqr. Yin Zhuming).
Izixhobo kunye nokusingqongileyo
A Inkqubo yezonyango enebhedi ezili-1,000ukudibanisa izibhedlele, ukuvuselelwa, kunye nezibonelelo zempilo-ezibonelela ngonyango olungenamthungo kwindawo indawo yokuphilisa eluhlaza negxile kwisigulane.
Ukugqwesa Kwezigulane Zamazwe Ngamazwe - Ukufikelela Okungenamthungo Kwihlabathi
Isixeko sezonyango saseTianjin esihlala ixesha elide
Iziko libonelela Iqonga lenkonzo yeVIP enyeyenzelwe iintsapho zamazwe ngamazwe ezifuna unyango olukumgangatho wehlabathi eTshayina.
Iinkonzo eziphambili:
Iingcebiso ze-AI zasimahla – Faka iirekhodi zonyango apha bioocus.com.
Uncedo lweelwimi ezininzi – IsiNgesi, iSpanish, nokunye; Abaququzeleli abafumaneka iiyure ezingama-24 ngosuku, iintsuku ezisixhenxe ngeveki.
Inkxaso yeVisa kunye nohambo – Ukudluliselwa kweenqwelo-moya, uxwebhu, kunye nokulungelelaniswa okupheleleyo kwezinto ezifunekayo.
Ukuhlawuliswa okucacileyo – Akukho zindleko zifihliweyo; iipakeji eziquka konke ziyafumaneka.
Ukufikelela okulula – Kuphela Imizuzu engama-30 ukusuka eBeijingngololiwe ohamba ngesantya esiphezulu.
Ukulandelelana Kwexesha Elide – Ukubeka esweni ukuchacha kunye nenkxaso yokubuyisela kwimeko yesiqhelo.
| Indawo yeNkonzo | Inzuzo ye-BIOOCUS Perennial |
| Uhambo | Ukufikelela kwiziko lesitimela + indawo yokuhlala yobunewunewu kwindawo |
| Ulungelelaniso | Inkonzo ye-VIP yeelwimi ezininzi efumaneka iiyure ezingama-24 ngosuku, iintsuku ezisixhenxe ngeveki |
| I-Visa kunye ne-inshurensi | Inkxaso epheleleyo yolawulo |
| Ukuchacha | Iinkqubo zokulungisa ezilungiselelwe wena |
Iqela lezonyango eliPhezulu - Iziqinisekiso ezikumgangatho wehlabathi
| Ingcali | Ubuchule | Iimbalasane |
| UNjingalwazi uLiang Han | I-Oncology yesisu | Amabhaso eSizwe, amaphepha angaphezu kwama-550, intsebenziswano no-MD Anderson |
| UDkt. Li Liming | I-Prostate kunye nezintso | INtloko yeTianjin Oncology; “Ugqirha oPhezulu” |
| UDkt. A.S. Pan Lekang | Umhlaza webele | I-MD/PhD yaseTokyo; iqeqeshwe eHarvard nase-ASCO |
| UGqr. Yao Yaqun | I-Immuno-Oncology | Iminyaka engama-40+ yobuchwephesha be-GI, imiphunga, kunye nomhlaza webele |
| Iingcali ezingaphezulu ezingama-20 | Utyando lweTyala, lweGynecologic, lwePlastiki | Abaqeqeshwe kumazwe ngamazwe, kuquka nabafundi abaphumelele kwi-MD Anderson |
IZiko le-BIOOCUS CGT – iSixeko sezonyango saseTianjin Perennial
Apho Ukuqamba Izinto Ezintsha Kudibana Novelwano.
Ukuhambisa unyango lwe-immunotherapy lwesizukulwana esilandelayokwaye ukhathalelo lwezigulane lwehlabathi—ukusuka ekuxilongweni ukuya ekupholeni.
Indalo, Iinkonzo Zezigulane, nokunye
I-Perennial Tianjin Medical City ayisiyonto yonyango kuphela—Imalunga nokudala indawo ekhuthazayo, egxile kwizigulane eyenza uhambo lwakho lwezempilo lube mnandi kwaye lungabi naxinzelelo. Le khampasi yenzelwe ngendlela ecingisisiweyo njengendawo eluhlaza, yanamhlanje eTianjin exakekileyo, eneendawo ezinkulu nezikhanyiswe kakuhle ezidibanisa itekhnoloji yanamhlanje kunye neendawo ezizolileyo ukukhuthaza ukuphiliswa kunye nokuphumla. Indawo yayo ephambili kufutshane nesikhululo sikaloliwe esikhawulezayo iqinisekisa ukufikelela okulula, nokuba uhamba ukusuka eBeijing, eShanghai, okanye kwamanye amazwe, ukunciphisa ukudinwa kokuhamba kunye nokuvumela ixesha elingakumbi lokuchacha.
Iinkonzo zethu zezigulane zenzelwe ukuba zidlule oko bekulindelwe, ngenkxaso yeelwimi ezininzi, izicwangciso zokhathalelo ezenzelwe wena, kunye nokugxila ekucaciseni izinto.—Akukho ntlawulo ifihliweyo, kukho iingcaciso ezicacileyo kunye neendlela onokukhetha kuzo. Yonwabela uncedo olukwinqanaba le-concierge, kubandakanya ucwangciso lweentlanganiso, ulungelelwaniso lwe-inshurensi (ngoku kubandakanya iinkqubo zikarhulumente), kunye neendawo zokuhlala zosapho kwiihotele ezikwindawo enamagumbi aphantse abe yi-1,000 kwiibhrendi ezine, ukusuka kubunewunewu ukuya kutsho kwinqanaba eliphakathi. Kwiindawo zokuhlala ezinde, uluntu oludibeneyo lokhathalelo lwabantu abadala lubonelela ngeebhedi ezili-1,800 ezinendawo yokuhlala epheleleyo, kubandakanya imisebenzi yoluntu efana neeworkshops zeti kunye neesalon zenkcubeko, ukuqinisekisa indawo exhasayo kubo bonke ubudala. Izinto ezongezelelweyo ezifana neendawo zokuthengisa, iindlela zokutyela, kunye neenkqubo zempilo-ntle ziyawonyusa amava akho, okwenza iPerennial Tianjin Medical City ingabi sisibhedlele nje kuphela, kodwa yindawo epheleleyo yempilo-ntle.
Iqela lezonyango le-BIOOCUS
Okthobha 2025