Isikhungo se-BIOOCUS CGT
Idolobha Lezokwelapha Elihlala Njalo laseTianjin
Ukwelashwa Kwamaseli, Izakhi Zofuzo, kanye Nezicubu Ezisezingeni Lomhlaba (CGT) Kweziguli Zomhlaba Wonke
Njengengxenye ye- Inethiwekhi Yezokwelapha Yomhlaba Wonke ye-BIOOCUS, iTianjin Perennial Medical City imi njenge Isikhungo esiyinhloko saseNyakatho China se-oncology yomuntu siqu kanye nemithi yokuvuselelaLesi sikhungo sihlanganisa ukwelashwa kwe-CAR-T, TIL, NK cell, kanye namaseli okuqala asezingeni eliphezulu, ukukhonza iziguli ezivela ngaphezu Amazwe angu-50 emhlabeni jikelele.
Kusukela ngo-2016, lesi sikhungo siye saphatha Iziguli ze-CAR-T eziyi-1,600(kusukela ngo-Okthoba 2025), ukufeza:
● Ukukhululwa kokuqala okungu-80–90%
●40–60% ukuxolelwa okuphelele kwesikhathi eside (CR)
● Izinga lokuphendula eliphelele elingu-95%+ (ORR)yomdlavuza we-hematologic
● Izinga lokulawula izifo elingu-60–92% (i-DCR)ngamathumba aqinile
Le miphumela isekelwa yi Ubuchwepheshe be-CAR-T obuthuthukisiwe be-IL-15, okuthuthukisa ukungena kwesimila, ukusinda kwamaseli e-T, kanye nokumelana nokuphuma kwe-antigen.
Ukwelapha kwe-CGT Okuphambili Ngemiphumela Yezokwelapha Eqinisekisiwe
Iphothifoliyo Yokwelapha Ephelele
Ukwelashwa kwe-CAR-T
lIzinhloso: CD19 / BCMA (hematologic), CLDN18.2 (amathumbu), GPC3 (isibindi/HCC), CEA (amaphaphu/NSCLC), B7H3 (glioma), GD2 (neuroblastoma)
lImiphumela: Kufika ku-90% CR yomdlavuza wegazi kanye nokulawulwa okubalulekile kwezifo kuzo zonke izinhlobo zezimila eziqinile.
Ukwelashwa kwe-TIL
lImiphumela: 40% ORR kanye no-80% ukwehla kwesimila ezigulini ezine-melanoma.
Ukwelashwa Kwamaseli E-NK kanye Ne-Stem Cell
lUkuhlanganisa imithi ye-ADC, ama-organoids esimila, kanye nokwelashwa nge-radionuclide (Y-90, Lu-177, Ac-225) ukuze kutholakale ukwelashwa okunembile komuntu siqu.
| Uhlobo Lomdlavuza | Ithagethi | Iziguli | I-ORR | I-DCR | Imiphumela Eyinhloko (Idatha ye-BIOOCUS) |
| Umdlavuza Wegazi | I-CD19 / BCMA | ~1,000 | 95%+ | – | 90% CR; 40–60% CR yesikhathi eside |
| Umdlavuza we-GI | I-CLDN18.2 | 98 | 38.8% | 91.8% | mPFS 4.4m; mOS 8.8m |
| Isibindi (i-HCC) | I-GPC3 | 32 | 56.6% | 86.7% | mPFS 13m; mOS 14.6m |
| Amaphaphu (i-NSCLC) | I-THE | 10 | 55.6% | 88.9% | I-OS yonyaka owodwa engu-77.8% |
| I-Glioma (rHGG) | B7H3 | 39 | 30–40% | 60–70% | mOS 11–13.6m |
| I-Melanoma | KU-TO | 12 | 40% | 80% | Ukuncipha kwesimila ngo-80% |
Iphrofayili Yokuphepha:
Iningi leziguli lizwa kuphela i-CRS emnene; akukho ama-ICANS noma ukufakwabikwa ezifundweni ezinkulu zezokwelapha.
I-Oncology Eqondile Yezifundo Ezihlukahlukene – Ukunakekelwa Okuhlanganisiwe Okukodwa
Idolobha Lezokwelapha Elihlala Njalo laseTianjin
I-BIOOCUS Tianjin Perennial inikeza ukuphathwa komdlavuza okuphelele, okusekelwe eqenjiningokusebenzisa ukwelashwa kwemikhakha eminingi (MDT)imodeli, ehlanganisa ukuhlinzwa, ukwelashwa okungenelelayo, ukwelashwa nge-immunotherapy, i-radiology, kanye nokunakekelwa okusekelayo.
Iminyango Eyinhloko Nochwepheshe
Ukuhlinzwa kanye ne-Oncology Yokungenelela:Ukwelashwa okungenasidingo kangako (i-nanoknife, i-cryoablation, i-RFA, i-laparoscopy) okuholwa yi- UProfesa Liang Han(umdlavuza wesisu) kanye UDkt. Li Liming(umdlavuza we-urological).
I-Oncology Yezokwelapha:Izindlela zokwelapha eziqondiswe ku-immuno ezithuthukisiwe ngaphansi UDkt. Yao Yaqun, onolwazi lweminyaka engaphezu kwengu-40 lwezokwelapha kumdlavuza we-GI, wamaphaphu, kanye nowebele
Imithi Yenuzi:Ubuciko obuphezulu Izithombe ze-PET-CTfuthi ukwelashwa kwe-radionuclide okuqondisiwe.
Ukwelashwa ngemisebe:Ihlonyiswe nge I-TOMO, Ummese we-Gamma, i-VMAT, i-SBRT, kanye ne-ARTizinhlelo; Ukwelashwa kwe-BNCT kanye ne-protonizoqala maduze.
Ukunakekelwa Okuphelele:Kuhlanganisiwe I-TCM, ukwesekwa kokudla okunempilo, ukwelashwa kwengqondo (uDkt. Wang Yulu), futhi ukuhlinzwa okwakha kabusha (uDkt. Yin Zhuming).
Izakhiwo Nemvelo
A Uhlelo lwezokwelapha olunemibhede eyi-1,000ukuhlanganisa izibhedlela, ukuvuselelwa, kanye nezikhungo zempilo enhle—okunikeza ukululama okungenazinkinga endaweni indawo yokuphulukisa eluhlaza futhi egxile esigulini.
Ubuhle Besiguli Samazwe Ngamazwe - Ukufinyelela Okungenamthungo Komhlaba Wonke
Idolobha Lezokwelapha Elihlala Njalo laseTianjin
Isikhungo sinikeza Ipulatifomu yesevisi ye-VIP eyodwayenzelwe imindeni yamazwe ngamazwe efuna ukunakekelwa okusezingeni lomhlaba eShayina.
Izinsizakalo Eziyinhloko:
Ukubonisana Kwamahhala Nge-AI – Layisha amarekhodi ezokwelapha ku- i-bioocus.com.
Usizo Lwezilimi Eziningi – IsiNgisi, iSpanishi, nokuningi; Abaxhumanisi bayatholakala amahora angama-24 ngosuku, izinsuku eziyi-7 ngesonto.
Usekelo lwe-Visa Nokuhamba - Ukudluliselwa kwezindiza, imibhalo, kanye nokuhlanganiswa okugcwele kwempahla.
Ukukhokhisa Okusobala - Azikho izindleko ezifihliwe; amaphakheji afaka konke ayatholakala.
Ukufinyelela Okulula – Kuphela Imizuzu engama-30 ukusuka eBeijingngesitimela esisheshayo.
Ukulandelela Kwesikhathi Eside - Ukuqapha ukululama okukude kanye nokusekelwa kokuvuselelwa.
| Indawo Yesevisi | Inzuzo Ehlala Njalo ye-BIOOCUS |
| Ukuhamba | Ukufinyelela kwesikhungo sesitimela + indawo yokuhlala yokunethezeka endaweni |
| Ukuxhumanisa | Isevisi ye-VIP yezilimi eziningi engu-24/7 |
| I-Visa kanye Nomshuwalense | Usekelo oluphelele lokuphatha |
| Ukululama | Izinhlelo zokuvuselela ezenzelwe wena |
Ithimba Lezokwelapha Elite - Iziqinisekiso Ezisezingeni Lomhlaba
| Uchwepheshe | Ubuchwepheshe | Okuvelele |
| UProfesa Liang Han | I-Gastric Oncology | Imiklomelo Kazwelonke, amaphepha angaphezu kuka-550, ukubambisana no-MD Anderson |
| UDkt. Li Liming | I-Prostate kanye Nezinso | Inhloko ye-Tianjin Oncology; “Udokotela Ophezulu” |
| UDkt. A.S. Pan Lekang | Umdlavuza Webele | Udokotela we-MD/PhD waseTokyo; waqeqeshwa eHarvard nase-ASCO |
| UDkt. Yao Yaqun | I-Immuno-Oncology | Iminyaka engaphezu kwengu-40 yobuchwepheshe be-GI, amaphaphu, kanye nomdlavuza webele |
| Ochwepheshe Abengeziwe abangu-20 | Ukuhlinzwa Kwesifuba, Odokotela Bezifo Zabesifazane, Ukuhlinzwa Kwepulasitiki | Abaqeqeshwe emhlabeni wonke, okuhlanganisa nabafundi be-MD Anderson abaphothule eyunivesithi |
Isikhungo se-BIOOCUS CGT – Idolobha Lezokwelapha Elihlala Njalo laseTianjin
Lapho Ukusungula Izinto Ezintsha Kuhlangana Nozwelo.
Ukulethwa ukwelashwa kwamasosha omzimba kwesizukulwane esilandelayofuthi ukunakekelwa kweziguli emhlabeni jikelele—kusukela ekuxilongweni kuya ekululameni.
Imvelo, Izinsizakalo Zeziguli, nokuningi
I-Perennial Tianjin Medical City ayiyona nje indaba yokwelapha—Kumayelana nokudala indawo enakekelayo, egxile esigulini eyenza uhambo lwakho lwezempilo lube lukhululekile futhi lungabi nokucindezeleka. Ikhampasi yaklanywa ngendlela ecatshangelwe kahle njengendawo eluhlaza, yesimanje eTianjin ephithizelayo, enezindawo ezinkulu nezikhanyiswe kahle ezihlanganisa ubuchwepheshe obusezingeni eliphezulu nendawo ethule ukukhuthaza ukuphulukiswa nokuphumula. Indawo yayo eyinhloko eduze kwesikhungo sesitimela esisheshayo iqinisekisa ukufinyelela okulula, kungakhathaliseki ukuthi uhamba usuka eBeijing, eShanghai, noma kwamanye amazwe, kunciphisa ukukhathala kokuhamba futhi kuvumele isikhathi esengeziwe sokululama.
Izinsizakalo zethu zeziguli zenzelwe ukwedlula okulindelwe, ngokusekelwa kwezilimi eziningi, izinhlelo zokunakekelwa komuntu siqu, kanye nokugxila ekubonakaleni—akukho mali efihliwe, izincazelo ezicacile nezinketho kuphela. Jabulela usizo lwezinga le-concierge, okuhlanganisa ukuhlela ama-aphoyintimenti, ukuxhumanisa umshwalense (manje okuhlanganisa nezinhlelo zikahulumeni), kanye nendawo yokuhlala yomndeni emahhotela asendaweni anamakamelo acishe abe yi-1,000 emikhiqizweni emine, kusukela kokunethezeka kuya kokuhlala okuphakathi nendawo. Ukuze uhlale isikhathi eside, umphakathi wokunakekelwa kwabadala ohlanganisiwe unikeza imibhede engu-1,800 enendawo yokuhlala ephelele yezokwelapha kanye neyomuntu omdala, okuhlanganisa imisebenzi yomphakathi efana nama-workshop etiye kanye nama-salon amasiko, okuqinisekisa indawo esekelayo yabo bonke ubudala. Izinsiza ezengeziwe ezifana nezindawo zokuthengisa, izinketho zokudlela, kanye nezinhlelo zokuphila kahle zithuthukisa ulwazi lwakho, okwenza i-Perennial Tianjin Medical City ingabi nje isibhedlela, kodwa indawo ephelele yempilo kanye nenhlalakahle.
Iqembu Lezokwelapha le-BIOOCUS
Okthoba 2025