- Ukwelashwa
- Ubufakazi
- I-Neuroblastoma
- Isimila Esiqinile
- Ubufakazi
- I-TILS
- Ukwelashwa Kwamaseli e-NK
- I-Myasthenia Gravis (MG)
- I-Acute Lymphoblastic Leukemia (B-ALL)
- I-Systemic Lupus Erythematosus (SLE)
- I-Acute Lymphoblastic Leukemia (T-ALL)
- I-Non-Hodgkin Lymphoma (NHL)
- I-Multiple Myeloma (MM)
- I-Diffuse Large B-cell Lymphom
- I-B-lymphocytic Leukemia
- I-Myeloma
Umjovo we-Nusinersen Sodium: Ithemba Lokuwohloka Kwemisipha Yomgogodla
Indlela Esebenza Ngayo
I-Nusinersen Sodiumkuyindlela yokwelapha i-oligonucleotide (ASO) elwa nokungezwani komzimba ehlose isakhi sofuzo se-SMN2.
Ngokushintsha inqubo yayo yokuhlanganisa, kuthuthukisa ukukhiqizwa kokusebenza Iphrotheni ye-SMN, kubalulekile ekusindeni nasekusebenzeni kwama-neuron okunyakaza.
Umuthi ufakwa ngqo ku-cerebrospinal fluid nge-lumbar puncture, ukuqinisekisa ukuthi ufinyelela ezindaweni ezithintekile ngempumelelo.
Izinzuzo Zemitholampilo
Uhlobo lwe-SMA I:
- Kukhulisa amazinga okusinda kweminyaka emibili kusukela ku-50% womlando kuya ngaphezu kuka-80%.
- Kuthuthukisa imisebenzi yokunyakaza njengokuhlala ngokuzimela kanye nokulawula ikhanda.
- Kunciphisa ukuthembela kuma-ventilator.
Uhlobo lwe-SMA II nolwesi-III:
- Kunciphisa ukuqhubeka kwesifo.
- Igcina noma ithuthukisa ukuhamba kwezingalo kanye nomsebenzi wokuphefumula.
- Ukwelashwa kwangaphambi kwezimpawu (isb., ezinsaneni ezisanda kuzalwa) kungaholela ekukhuleni kwemisipha cishe evamile.
Umphumela Wesikhathi Eside:
- Idatha yokulandelela yeminyaka emihlanu ikhombisa ukuthuthuka okuzinzile kokusebenza kwemisipha ngaphandle kokwehla okukhulu.
Ukufinyelela Komhlaba Wonke:
- Kusukela ekuvunyelweni kwayo yi-FDA ngo-2016, iziguli ezingaphezu kuka-100,000 emazweni angaphezu kuka-60 ziye zazuza, zimboza zonke izinhlobo ze-SMA.
Ubufakazi Obuvela Ocwaningweni
Izivivinyo zemitholampilo (isib., UKUMUKELA, UKUTHANDA, UKUHLONIPHA) ezihilela Iziguli ezingu-274 bonisa ukuthuthukiswa okuphawulekayo:
- Impendulo yesinyathelo semoto: Ingcono ngo-51% kunamaqembu okulawula (p
- Ukuthuthukiswa kwamaphuzu e-HINE-2: 26% ingcono kunezilawuli (p
Izifundo kubantu abasebasha nakubantu abadala zibonisa futhi amaphuzu okusebenza kwemisipha athuthukisiwe (isb., i-HFMSE, i-RULM) ngemva kwezinyanga ezingu-26.
Intengo ku-BIOOCUS
MinaUmjikelezo Wokuqala Wokwelashwa (Imijovo Emi-4): Iphakheji ephelele engu-$200,000, kufaka phakathi:
- Izindleko zemithi: $50,000 ngomjovo ngamunye.
- Imali yokujova, yokuwadi, kanye nemali yokuhlolwa.
- Izinsizakalo zokudluliselwa esikhumulweni sezindiza kanye nezokuthutha ezibandayo.
Ngemva Kokwelashwa: Iziguli zingayithatha idosi yesine ziye nayo ekhaya ebhokisini elibandayo elingu-2-8°C futhi zithole ukwesekwa kwemithamo yokunakekela njalo ezinyangeni ezi-4.
MinaUkuqhathaniswa Kwezindleko Zamazwe Ngamazwe
| Izwe/Isifunda | Izindleko ngomjovo ngamunye (i-USD) | Isamba samaDosi okulayisha angu-4 (i-USD) | Izindleko Zonyaka Wokuqala (i-USD) | Amanothi |
| I-BIOOCUS, eShayina | 50,000 | 200,000 | 200,000 (okokuqala) | Kufaka phakathi izinsizakalo ezigcwele |
| I-united states | 125,000 | 500,000 | 750,000 (imijovo engu-6) | Azikho izibonelelo |
| I-Australia | 87,500 (Akukho xhaso) | 350,000 | 525,000 (imijovo engu-6) | I-PBS Ixhaswe Ngezimali
|
UkongaIntengo ye-BIOOCUS inikeza ukwehliswa kwezindleko okufika ku-60% uma kuqhathaniswa namanani angaxhaswanga e-US nase-Australia.
Ukunakekelwa Okuphelele Kweziguli Zamazwe Ngamazwe
Sinikeza ukwesekwa okumangalisayo kweziguli zamazwe ngamazwe ezifuna ukwelashwa eShayina, siqinisekisa okuhlangenwe nakho okungenazihibe nokukhululekile.
Ngaphambi Kokwelashwa
- Ukubonisana Ngezokwelapha: Izinhlelo zokwelapha ezenzelwe wena ngokusekelwe kumarekhodi esiguli.
- Ithimba Lochwepheshe: Ukuxilongwa kwezifundo eziningi ngokunemba.
- Ukuthutha: Usizo lwe-visa, ukuhlanganiswa kwediphozithi, kanye namalungiselelo endiza.
Ngesikhathi Sokwelashwa
- Indawo yokuhlala nokuhamba: Kuhlelwe ukuhlala ehhotela kanye nokudluliselwa esikhumulweni sezindiza.
- Ukunakekelwa KwezokwelaphaUkwelashwa e-China Nuclear Medical Health Management Center, okubandakanya ubuchwepheshe obuthuthukisiwe nabasebenzi abanekhono.
- Uhlelo Lokufaka Umjovo: Kunikezwa ngosuku 1, 14, kanye no-28, kanye nokubhekwa kokuphepha kwamahora ayi-6 ngemva kokujova.
Ngemva Kokwelashwa
- Umthamo Wokuthatha Uhambe Nawo Ekhaya: Umjovo wesine unikezwa ebhokisini leketanga elibandayo.
- Ukusekelwa Okuqhubekayo: Usizo ngemithamo yokulungisa njalo ezinyangeni ezi-4, okuhlanganisa ukuthengwa nokuthunyelwa.
Izinsizakalo Ezengeziwe
- Ukuxhumana: Ukusethwa kwe-WhatsApp ne-WeChat ukuze kube lula ukuxhumana.
- Ukufinyelela kwe-VIP: Izinsizakalo zezokwelapha ezisheshayo ngamaqembu azinikele.
- Izidingo Zansuku Zonke: Ukusekelwa kwendawo yokuhlala, ezokuthutha, ukudla, ukuyothenga, kanye nokuhumusha kobungcweti.
Submit An Free Inquiry
Our medical team will make an evaluation for you, based on the information you provided. This procedure is free of charge.