- Ukwelashwa
- Ubufakazi
- I-Neuroblastoma
- Isimila Esiqinile
- Ubufakazi
- I-TILS
- Ukwelashwa Kwamaseli e-NK
- I-Myasthenia Gravis (MG)
- I-Acute Lymphoblastic Leukemia (B-ALL)
- I-Systemic Lupus Erythematosus (SLE)
- I-Acute Lymphoblastic Leukemia (T-ALL)
- I-Non-Hodgkin Lymphoma (NHL)
- I-Multiple Myeloma (MM)
- I-Diffuse Large B-cell Lymphom
- I-B-lymphocytic Leukemia
- I-Myeloma
Ukwelashwa Ngegciwane Le-Oncolytic: Ukwelashwa Komdlavuza Okuthuthukisiwe
Kusebenza Kanjani Ukwelashwa Ngegciwane Le-Oncolytic?
Lokhu kwelashwa kusekelwe ku-adenovirus yohlobo 5 eguquliwe eyenziwe ngofuzo ukuze:
- Ziphindaphindeke ngokukhetha kumaseli esimila: Leli gciwane lihlasela ngqo amangqamuzana omdlavuza ngenkathi lishiya amangqamuzana avamile, aphilile engenamyocu
- Bonakalisa ngqo amangqamuzana omdlavuzaNjengoba igciwane liphindaphinda ngaphakathi kwamaseli esimila, libangela ukuba aqhekeke futhi afe
- Yenza isimiso sakho somzimba sisebenze: Ukubhujiswa kwamangqamuzana omdlavuza kukhipha ama-antigen esimila aqaphelisa futhi agqugquzele izivikelo zemvelo zomzimba wakho ukuze zilwe nomdlavuza
- Dala impendulo ehlala njalo yomzimba: Le ndlela ekabili—ukubulala amagciwane ngokuqondile kanye nokusebenza komzimba—inikeza isibhakela esinamandla sokulwa nomdlavuza
Ubani Ongazuza Ngokwelashwa Ngegciwane Le-Oncolytic?
Ukwelashwa ngegciwane le-oncolytic kungafaneleka ezigulini ezine:
Izinkomba Ezivunyelwe Njengamanje:
- Umdlavuza wesinyi ongenayo imisipha (i-NMIBC)eyehlulekile noma engaphenduli ekwelashweni kwe-BCG (Bacillus Calmette-Guérin)
- Iziguli ezinomdlavuza wesinyi ezisengozini ephakathi kuya kwephezulu ezifuna ezinye izindlela zokuhlinzwa
Ngaphansi Kophenyo Lwezokwelapha:
- Izimila ezahlukahlukene eziqinile ezingaphendulanga ekwelashweni okujwayelekile
- Umdlavuza we-gynecologic oqhubekayo, ophindaphindayo, noma osakazekayo ohlanganisa:
- Umdlavuza wesibeletho
- Umdlavuza wesibeletho
- Umdlavuza wesitho sangasese sowesifazane
- Umdlavuza we-vulvar
- Umdlavuza wesisu
- Amanye amathumba aqinile athuthukile
Ukuphathwa Kokwelashwa
Iphrothokholi Yomdlavuza Wesinye:
- Indlela yokulethwa: Ukufakwa kwesinyi ngqo (ukuphathwa nge-intravesical)
- Umthamo: 75 mL yesisombululo segciwane le-oncolytic (1×10¹⁰ IFU/mL)
- Uhlelo lokwelashwa:
-
- Isigaba sokungeniswa: Ukwelashwa kwamasonto onke amasonto angu-1-6 kuye ngeqembu lokwelashwa
- Isigaba sokunakekela: Ukwelashwa okwenziwa ngezikhathi ezithile ukuze kugcinwe ukulawulwa kwezifo
- Isikhathi sokwelashwa: Kufika eminyakeni emi-2 kuye ngempendulo yomuntu ngamunye
Amanye Amathumba Aqinile:
- Indlela yokulethwa: Ukujova okuqondile ngaphakathi kwesimila emathunjini afinyelelekayo
- Ukulinganisa okwenziwe ngokwezifiso: Ngokusekelwe kusayizi wesimila nendawo
- Imijikelezo yokwelapha: Ngokuvamile izinsuku ezi-5 zilandelana ngomjikelezo ngamunye, imijikelezo iphindaphindwa ngokusekelwe empendulweni
Okufanele Ukulindele Ngesikhathi Sokwelashwa
Ukulungiselela ukwelashwa kwangaphambi kokwelashwa:
Kubantu abanomdlavuza wesinye, kufakwa i-catheter, bese kulungiswa isinye ngesisombululo sokuhlanza esithambile ngaphambi kokuphathwa kwegciwane le-oncolytic.
Ngesikhathi Sokwelashwa:
- Yonke inqubo yenziwa njengokuvakashela isiguli ngaphandle kwesibhedlela
- Ukufakwa kwesinyi kuthatha cishe amahora angu-1-2
- Iziguli zicelwa ukuthi zishintshe izikhundla njalo ngemizuzu eyi-15 ukuqinisekisa ukuthi zitholakala ngokuphelele odongeni lwesinye
- Ngemva kwesikhathi sokugcina, ikhambi likhishwa ngokwemvelo
Imiphumela Emibi Evamile:
Ukwelashwa ngegciwane le-oncolytic ngokuvamile kubekezelelwa kahle. Imiphumela emibi evame kakhulu ihlanganisa:
- Imfiva(70% weziguli)—ngokuvamile ithambile futhi ilawuleka ngemithi ejwayelekile
- Ukukhathala
- Izimpawu ezifana nomkhuhlane
- Ukungakhululeki kwendawo lapho kujovwa noma kufakwe khona umjovo
- Izimpawu zesikhashana zomchamo (zeziguli ezinomdlavuza wesinyi)
Okubalulekile: Imiphumela emibi eminingi isukela ku-Grade 1 kuya ku-2 (encane kuya kwephakathi) kanye neyesikhashana. Izehlakalo ezimbi kakhulu azivamile (ngaphansi kuka-10% weziguli).
Ubufakazi Bezokwelapha
Imiphumela Yomdlavuza Wesinye:
Lokhu kwelashwa ngegciwane le-oncolytic okwamanje kusezivivinyweni zezokwelapha zeSigaba II zomdlavuza wesinyi ongaphenduli we-BCG, kanye nalokhu:
- Iziguli eziyi-180 zihlelelwe ukubhaliswa
- Izikhungo zokwelapha eziningi kulo lonke elaseShayina
- Ukuqapha okuqinile ukuphepha nokusebenza kahle
Umdlavuza Wezinsikazi:
Ucwaningo olubukeziwe lweziguli ezingu-29 ezinomdlavuza wezifo zabesifazane oqhubekayo, ophindaphindayo, noma osabalele lubonise:
- Izinga lokuphendula lilonke elingu-40%
- Ukulawula kwendawo okuphelele okungu-80% ezinyangeni ezi-3
- Izimpendulo ezibonwe kuzo zonke izinhlobo zomdlavuza wesibeletho, wesibeletho, wesitho sangasese sowesifazane, kanye nowesitho sangasese sowesifazane
- Ukulandelela okuphakathi kwezinyanga ezingu-6.3 ngokulawulwa kwezifo okuqhubekayo
- Imiphumela emibi engaphezu kuka-90% yayincane (Ibanga 1-2)
Izindlela zokwelapha ezifanayo ze-Oncolytic Virus:
Izindlela zokwelapha ze-adenovirus ezibangelwa yi-oncolytic ezihlobene (njenge-H101) zibonise:
- Ukuvunyelwa nokusetshenziswa ngempumelelo komdlavuza wekhanda nentamo eShayina kusukela ngo-2005
- Imiphumela ethembisayo uma ihlanganiswa ne-chemotherapy kanye nemisebe
- Amandla okuguqula izimila ezingasebenzi zibe yisifo esingasuswa ngokuhlinzwa
Ukufinyelela Ukwelashwa Ngegciwane Le-Oncolytic eShayina kwa-BIOOCUS
Sigxile ekuxhumeni iziguli zomhlaba wonke nezindlela zokwelapha ezithuthukisiwe ezitholakala eShayina, okuhlanganisa nokwelashwa ngegciwane le-oncolytic. Sihlinzeka:
- Ukuhlolwa okuphelele: Ukuhlolwa kokufaneleka kwakho kulolu hlobo lokwelashwa
- Ukuxhumana kwezokwelapha: Ukuxhumana nezikhungo zomdlavuza ezihamba phambili ezenza izivivinyo zemitholampilo zegciwane le-oncolytic
- Ukuhlela ukwelashwa: Usekelo oluphelele lwezokuthutha ohambweni lwakho lokwelashwa
- Ukusekelwa kolimi: Abaxhumanisi bezokwelapha abakhuluma isiNgisi kulo lonke ukunakekelwa kwakho
- Ukuqapha okuqhubekayo: Ukuxhumana kokunakekelwa okulandelayo nodokotela bakho basekhaya
Ulwazi Olubalulekile Lokuphepha
Obani Okungafanele Bathole Ukwelashwa Ngegciwane Le-Oncolytic:
- Iziguli ezine-hepatitis B esebenzayo, i-HIV, noma isifo sofuba
- Iziguli ezidinga imithi yokucindezela amasosha omzimba
- Abesifazane abakhulelwe noma abancelisayo
- Iziguli ezine-immunodeficiency enzima
Izinyathelo Zokuqapha Ezikhethekile:
- Abahlinzeki bezempilo kanye namalungu omndeni bathatha izinyathelo ezijwayelekile zokulawula ukutheleleka
- Leli gciwane lenzelwe ukuzala kuphela kumaseli esimila futhi alithelelani phakathi kwabantu.
- Iziguli kufanele zazise bonke abahlinzeki bezempilo mayelana nokwelashwa kwazo ngegciwane le-oncolytic
Izinyathelo Ezilandelayo
Uma wena noma othandekayo wakho kutholakale ukuthi unomdlavuza wesinyi ongazweli ku-BCG noma ezinye izimila eziqinile okunzima ukuzelapha, ukwelashwa ngegciwane le-oncolytic kungakunikeza ithemba elisha.
Ukuze ufunde ukuthi uyakufanelekela yini lokhu kwelashwa:
- Xhumana nethimba lethu lezinsizakalo zeziguli mayelana namarekhodi akho ezokwelapha
- Thola ukuhlolwa kokufaneleka kokuqala
- Hlela ukubonisana nochwepheshe bethu bezokwelapha
- Yakha uhlelo lokwelashwa oluqondene nawe
Submit An Free Inquiry
Our medical team will make an evaluation for you, based on the information you provided. This procedure is free of charge.