Lapaʻau Virus Oncolytic: Lapaʻau Kanesa Holomua

Hoʻomākaukau mua no ka mālama ʻana:

No nā poʻe maʻi maʻi ʻōpū mimi, hoʻokomo ʻia kahi catheter, a ua hoʻomākaukau ʻia ka ʻōpū mimi me kahi wai hoʻomaʻemaʻe mālie ma mua o ka hoʻokele ʻana i ka maʻi oncolytic.

I ka wā o ka mālama ʻana:

• Hana ʻia ke kaʻina hana holoʻokoʻa ma ke ʻano he kipa outpatient
• ʻO ka hoʻokomo ʻana o ka ʻōpū mimi e lawe ma kahi o 1-2 mau hola
• Ua noi ʻia nā maʻi e hoʻololi i nā kūlana i kēlā me kēia 15 mau minuke e hōʻoia i ka hōʻike piha ʻana o ka paia o ka ʻōpū mimi
• Ma hope o ka manawa mālama, ua kipaku maoli ʻia ka hopena

Nā hopena ʻaoʻao maʻamau:

Hoʻomanawanui maikaʻi ʻia ka lāʻau lapaʻau oncolytic virus. ʻO nā hopena ʻaoʻao maʻamau:

• kuni(70% o nā maʻi)—ʻoluʻolu a hiki ke hoʻokele ʻia me nā lāʻau lapaʻau maʻamau
• Luhi
• Nā hōʻailona e like me ka maʻi flu
• ʻO ka ʻeha kūloko ma kahi o ka injection a i ʻole ka instillation
• Nā hōʻailona mimi no ka manawa pōkole (no nā maʻi maʻi ʻaʻai mimi)

KoʻikoʻiʻO ka hapa nui o nā hopena ʻaoʻao he Papa 1-2 (ʻoluʻolu a kaulike) a no ka manawa pōkole. He mea maʻamau ʻole nā ​​​​hanana ʻino koʻikoʻi (ʻaʻole i hiki i ka 10% o nā maʻi).

Nā Hopena o ke Kanesa ʻŌpū Mimi:

Aia kēia lāʻau lapaʻau oncolytic i nā hoʻokolohua lapaʻau Phase II no ka maʻi ʻaʻai ʻōpū pane ʻole BCG, me:

• 180 mau maʻi i hoʻolālā ʻia no ke kākau inoa ʻana
• Nā kikowaena lapaʻau he nui ma Kina
• Ka nānā pono ʻana i ka palekana a me ka pono

Nā maʻi ʻaʻai wahine:

Ua hōʻike ʻia kahi noiʻi retrospective o 29 mau maʻi me nā maʻi kanesa gynecologic mau, recurrent, a metastatic paha:

• 40% ka nui o ka pane holoʻokoʻa
• 80% ka mana kūloko piha i 3 mahina
• Nā pane i ʻike ʻia ma waena o nā maʻi ʻaʻai cervical, ovarian, vaginal, a me vulvar
• ʻO ka hahai ʻana ma waena o 6.3 mau mahina me ka kaohi mau ʻana i nā maʻi
• Ma luna o 90% o nā hopena ʻaoʻao he akahai (Papa 1-2)

Nā Lapaʻau Virus Oncolytic like:

Ua hōʻike ʻia nā lāʻau lapaʻau adenovirus oncolytic pili (e like me H101):

• ʻAe ʻia a me ka hoʻohana kūleʻa ʻana i nā maʻi ʻaʻai poʻo a me ka ʻāʻī ma Kina mai ka makahiki 2005
• Nā hopena hoʻohiki i ka wā e hui pū ʻia me ka chemotherapy a me ka radiation
• Ka hiki ke hoʻololi i nā ʻōpū hiki ʻole ke hana ʻia i nā maʻi hiki ke ʻoki ʻia e ke ʻoki

He loea mākou i ka hoʻopili ʻana i nā maʻi o ka honua me nā ʻano lapaʻau holomua i loaʻa ma Kina, me ka lāʻau lapaʻau oncolytic virus. Hāʻawi mākou i:

• Loiloi piha: Ka loiloi ʻana i kou kūpono no kēia lāʻau lapaʻau
• Hoʻonohonoho lapaʻauʻO ka pilina me nā kikowaena maʻi kanesa alakaʻi e hana ana i nā hoʻokolohua lapaʻau oncolytic virus
• Hoʻolālā lapaʻauKākoʻo logistical piha no kāu huakaʻi lapaʻau
• Kākoʻo ʻōlelo: Nā mea hoʻonohonoho lapaʻau ʻōlelo Pelekania ma o kāu mālama ʻana
• Ke nānā mau nei: Ka hoʻonohonoho ʻana i ka mālama ʻana me kāu mau kauka home

ʻO wai ka mea pono ʻole e loaʻa i ka lāʻau lapaʻau Oncolytic Virus:

• Nā maʻi me ka hepatitis B ikaika, HIV, a i ʻole ka maʻi puʻupuʻu
• Nā maʻi e pono ai nā lāʻau lapaʻau immunosuppressive
• Nā wahine hāpai a hānai waiū paha
• Nā maʻi me ka immunodeficiency koʻikoʻi

Nā Mālama Kūikawā:

• Lawe nā mea lawelawe olakino a me nā ʻohana i nā hana palekana maʻamau no ka pale ʻana i ka maʻi
• Ua hoʻolālā ʻia ka maʻi e hana hou wale i loko o nā pūnaewele tumo a ʻaʻole ia e laha ma waena o nā kānaka
• Pono nā maʻi e hoʻomaopopo i nā mea lawelawe olakino āpau e pili ana i kā lākou mālama ʻana i ka maʻi oncolytic

Inā ua ʻike ʻia ʻoe a i ʻole kekahi mea aloha me ka maʻi ʻaʻai mimi ʻole i pane ʻole i ka BCG a i ʻole nā ​​​​​​maʻi puʻupuʻu paʻakikī e mālama, hiki i ka lāʻau lapaʻau oncolytic virus ke hāʻawi i ka manaʻolana hou.

No ka ʻike inā kūpono ʻoe no kēia lāʻau lapaʻau:

1. E hoʻokaʻaʻike aku i kā mākou hui lawelawe maʻi me kāu mau moʻolelo lapaʻau
2. E loaʻa i kahi loiloi kūpono mua
3. E hoʻonohonoho i kahi kūkākūkā me kā mākou poʻe loea lapaʻau
4. E hoʻomohala i kahi hoʻolālā lapaʻau pilikino