Pane Kupaianaha i ka Myeloma Multiple Refractory Ma hope o ka CAR-T Cell Therapy

ʻIkepili o ka mea maʻiʻO Mr. Mohamed H., he kāne 70 makahiki mai ʻAigupita mai

Ka Hōʻailona MuaʻO ka myeloma lehulehu me ka hoʻopili ʻana o ka iwi ākea. Ua hōʻike ʻo PET/CT ma mua o ka mālama ʻana (Iulai 2024) i nā ʻeha iwi hypermetabolic nui ma loko o ka iwi axial a me ka appendicular, me nā ʻeha luku he nui a me ka SUV kiʻekiʻe loa o 17.9, e hōʻike ana i ka maʻi ikaika loa.

LapaʻauMa hope o ka holomua ʻana i ka chemotherapy maʻamau, ua ʻimi ʻo Mr. Mohamed i nā koho holomua a koho iā Bioocus no ka immunotherapy cell CAR-T i hoʻolālā ʻia.

Nā Hopena Hahai (Kepakemapa 2024 - wale nō ~2 mau mahina ma hope o ka hoʻōla ʻana)Ua hōʻike ʻia ka hana hou ʻana o ka PET/CT o ke kino holoʻokoʻa:

• Ka emi nui ʻana o ka hana metabolic ma aneane nā ʻeha i hana mua ʻia
• Ua hoʻopau loa ʻia nā ʻeha he nui (ʻaʻohe lawe ʻana o FDG maʻamau)
• Ua hāʻule ka SUV kiʻekiʻe loa mai 17.9 a i 5.16
• ʻO ka lawe ʻana o ka momona diffuse akahai wale nō i koe, e kūlike me nā loli reactive ma hope o ka mālama ʻana
• ʻAʻohe foci hypermetabolic hou i loko o ka iwi a i ʻole nā ​​​​ʻiʻo palupalu

Ua lilo ʻo Mr. Mohamed i mea hōʻike ʻole i nā hōʻailona ma hope koke iho o ka hoʻokomo ʻia ʻana o ka infusion. Ua hōʻike ʻo ia ua loaʻa hou ka ikaika, ʻaʻohe ʻeha o ka iwi, a ua hoʻi hou i ke ola maʻamau o kēlā me kēia lā - nā hopena āna i wehewehe ai he "manawa lua."

"Ma mua o ka ʻeha ma nā wahi āpau, a ua manaʻo wau ʻo kēia ka hopena. Ma hope o ka mālama ʻana iā CAR-T ma Bioocus, ua like wau me he kanaka hou lā. Ua hōʻike ka scan hou loa ua aneane nalowale ke kanesa. Mahalo nui wau." — Mr. Mohamed H.

Hōʻike kēia hihia i ka mana nui o ka lāʻau CAR-T i ka hoʻokō ʻana i nā pane wikiwiki a hohonu, ʻoiai i nā poʻe maʻi ʻelemakule me ka myeloma multiple holomua, i mālama mua ʻia.