Mhinduro Inoshamisa muRefractory Multiple Myeloma Mushure meCAR-T Cell Therapy

Nhoroondo yeMurwereVaMohamed H., murume ane makore makumi manomwe ekuberekwa anobva kuEgypt

Kuongorora KwekutangaMultiple myeloma ine mapfupa akawanda. PET/CT isati yatanga kurapwa (Chikunguru 2024) yakaratidza mapfupa akawanda asina metabolic mumuviri wese, aine mapfupa akawanda anoparadza uye SUV yepamusoro ye17.9, zvichiratidza kuti chirwere chacho chakanyanya kushanda.

KurapaMushure mekuenderera mberi nekurapwa kwemishonga yechivanhu, VaMohamed vakatsvaga nzira dzepamusoro uye vakasarudza Bioocus yekurapa neCAR-T cell immunotherapy.

Mhedzisiro Yekutevera (Gunyana 2024 - mwedzi miviri chete mushure mekurapwa)Kudzokorora kwePET/CT yemuviri wese kwakaratidzwa:

• Kudzikira kukuru kwemabasa ekugadzirisa muviri muzvironda zvinenge zvese zvaimboshanda
• Maronda mazhinji apera zvachose (hapana kutorwa kweFDG kusingawanzoitika)
• SUV yepamusoro yakadzikira kubva pa17.9 kusvika pa5.16
• Kutora manyoka munyoro chete kwakasara, zvichienderana nekuchinja kwemaitiro mushure mekurapwa.
• Hapana foci itsva ye hypermetabolic mumapfupa kana munyama yakapfava

VaMohamed vakatanga kusaratidza zviratidzo zvachose mushure mekupihwa mushonga uyu. Vanoti vawana simba idzva, havana kurwadziwa nemapfupa, uye vadzokera kuhupenyu hwavo hwezuva nezuva - mhedzisiro yavanoti "mukana wechipiri."

"Marwadzo asati amboonekwa, uye ndaifunga kuti ndiwo waive mugumo. Mushure mekurapwa kweCAR-T kuBioocus, ndinonzwa semunhu mutsva. Kuongororwa kwazvino kunoratidza kuti kenza yava kuda kupera. Ndinotenda zvikuru." — VaMohamed H.

Nyaya iyi inoratidza kugona kukuru kwekurapa kweCAR-T mukuwana mhinduro dzinokurumidza uye dzakadzika, kunyangwe kune vakwegura vane multiple myeloma yakatokura uye yakamborapwa zvakanyanya.