Mibvunzo Inowanzo bvunzwa-Kurapa

Mubvunzo.
Chii chinonzi kuisirwa ropa nemapfupa (BMT)?

A.

Kuisirwa ropa nemapfupa mumongo inzira yakakosha yekurapa vanhu vane mamwe marudzi egomarara kana mamwe matambudziko emapfupa mumongo. Muisirwa ropa nemapfupa mumongo, masero anowanzo kuwanikwa mumongo mumongo anotorwa, ogadzirwa uye odzoserwa kumurwere kana mumwe munhu. Chinangwa chekuisirwa ropa nemapfupa mumongo ndechekupa munhu masero emapfupa ane hutano mushure mekunge mabhonzo avo asina hutano abviswa.

Kuisirwa ropa nemapfupa zvakashandiswa zvinobudirira kubvira muna 1968 kurapa zvirwere zvakaita se leukaemia, lymphoma, aplastic anemia, immunodeficiency disorders pamwe nemamwe magomarara egomarara.
Mubvunzo.
Inguva yakadini inofungidzirwa yekugara muchipatara yeBMT?

A.
Kana munhu achizora mapfupa emubofu, zvinofungidzirwa kuti kugara muchipatara kunofanira kuva kwemavhiki mana kusvika matanhatu. Zvisinei, unofanira kugara muguta kwemwedzi mitanhatu kana kupfuura sezvo zvichidikanwa kuti urambe uchiongororwa mushure meBMT.
Mubvunzo.
Ndiani anogona kubatsirwa nekuisirwa ropa nemapfupa (BMT)?

A.
Zvirwere zvinotevera ndizvo zvinonyanya kubatsirwa nekuisirwa ropa kana mufuva:

- Leukaemia

- Kushaya ropa kwakanyanya

- Lymphoma

- Multiple myeloma

- Zvirwere zvekushaya simba remuviri
Mubvunzo.
Chii chinonzi CAR-T therapy?

A.
Kurapa nemasero eChimeric antigen receptor T (CAR-T) inzira itsva yekurapa mhando dzakasiyana dzekenza. Pfungwa yacho ndeyekubvisa masero eT emurwere uye kuagadzira majini kuti abudise chimeric antigen receptor (CAR) inoziva antigen chaiyo inobatanidzwa netumor (TAA). Nekuda kweizvozvo, kana masero eT-expressing CAR adzorerwa mumuviri wemurwere, anonanga uye anobvisa masero etumor anotsanangura TAA.
Mubvunzo.
Varwere vapi vanobatsirwa neCAR-T?

A.
Kuedzwa kwekiriniki yeCAR-T ndekwevarwere vane B-cell acute lymphoblastic leukaemia (B-ALL), B-cell lymphoma uye multiple myeloma vakadzokera kuchirwere kana kuti vakaramba kushandisa chemotherapy.
Mubvunzo.
Tinofanira kugara muchipatara kwenguva yakareba sei tichirapwa neCAR-T?

A.

Kuedzwa kwekiriniki yeCAR-T kunotora mavhiki angangoita matanhatu kusvika masere, zvichienderana nemamiriro emurwere wega wega.
Mubvunzo.
Ndeipi nzira yekurapa CAR-T?

A.
Mubvunzo.
Waita CAR-T kangani?

A.
Kubva mugore ra2015, tapedza miedzo inosvika mazana matatu yeCAR-T yekurapa B-ALL, B-cell lymphoma uye multiple myeloma isina kusimba, uye tawana mhedzisiro yakanaka kwazvo. Takapfupikisa nyaya dzekutanga makumi mashanu nerimwe ndokudziburitsa muJournal of Leukemia muna 2017.
Mubvunzo.
Mwero wekubudirira kwako muCAR-T wakaita sei?

A.
Mwero wekuregererwa kwese kwese waive kupfuura 90%.
Mubvunzo.
Chii chinobatsira pakuisirwa bofu mushure meCAR-T?

A.
Kunyangwe huwandu hwekuregererwa kwakakwana (CR) kwekurapwa kweCAR-T hwakakwira, kuchine njodzi yekudzoka zvakare. Zvidzidzo zvakaratidza kuti kubatanidza BMT mushure meCAR-T yeB-ALL kunogona kuwedzera huwandu hwekurapa hunogona kuitika.
Mubvunzo.
Ndingawana sei nguva yekusangana nevamwe?

A.
Unogona kuwana musangano kuburikidza nevamiriri vedu vemadhipatimendi epasi rose.
Mubvunzo.
Ndeapi magwaro andinofanira kuuya nawo?

A.
Zvakakosha kuti paunenge uchifamba uve nemagwaro ese akakodzera anosanganisira kopi yemishumo yese yezvekurapa, mishumo yezvirwere zvinosanganisira masiraidhi egirazi uye paraffin blocks izvo zvichadikanwa kuti zviongororwe, mifananidzo yemhedzisiro yeCT, MRI, PET-CT scan, blood routine, immune histochemistry, genetic testing, chromosome results kana dziripo.
Mubvunzo.
Ndiani achandipa nguva yekuonana nechiremba uye purogiramu yangu panguva yandiri muchipatara?

A.
Chikwata chedu chepasi rose chichabhuka nguva yekusangana nevarwere uye chicharonga nguva yekutevera varwere paunenge uri muchipatara.
Mubvunzo.
Ndeipi nzira yekuti varwere vatsvage mazano ekurapa?

A.
Vashandi vedu veInternational Centre vane chinangwa chekupa mukana wakajeka uye rubatsiro rwakasiyana-siyana kune varwere vedu vekune dzimwe nyika. Vashandi vedu vachavepo kuti vabatsire varwere vese padanho rega rega rekurapwa kwavo.
Mubvunzo.
Ndingawana here mushumo wenyaya yangu mushure mekurapwa?

A.
Ehe, mushure mekurapwa, tichashandura mushumo wenyaya yenyu tokupai mushumo wenyaya muchiRungu nechiChinese kuitira kuti mukwanise kuudzosa kunyika yenyu.
Mubvunzo.
Pane angandibatsira here kuenda kunhandare yendege pandichadzoka kumba mushure mekurapwa?

A.
Ehe, vashandi vedu veInternational Center vachakuchengetera mota uye vachakubatsira kuisa mitoro yako mumotokari uye kukuendesa kunhandare yendege.