Mafunso Ofunsidwa Kawirikawiri - Chithandizo

Q.
Kodi kuyika magazi ndi mafuta m'thupi (BMT) n'chiyani?

A.

Kuika magazi ndi mafuta a m'mafupa ndi njira yapadera yothandizira anthu omwe ali ndi mitundu ina ya khansa kapena matenda ena a m'mafupa. Poika magazi ndi mafuta a m'mafupa, maselo omwe amapezeka m'mafupa amatengedwa, kukonzedwa ndikubwezeredwa kwa wodwala kapena munthu wina. Cholinga cha kuika magazi ndi mafuta a m'mafupa ndi kupatsa munthu maselo a m'mafupa athanzi pambuyo poti mafuta awo a m'mafupa osadwala achotsedwa.

Kuika magazi ndi mafuta a m'mafupa kwakhala kukugwiritsidwa ntchito bwino kuyambira mu 1968 pochiza matenda monga khansa ya m'magazi, lymphoma, kuchepa kwa magazi m'thupi, matenda a chitetezo chamthupi komanso khansa zina zotupa.
Q.
Kodi nthawi yoti munthu akhale m'chipatala cha BMT ndi yotani?

A.
Pakuika mafupa, munthu ayenera kukhala kuchipatala kwa milungu 4-6. Komabe, muyenera kukhala mumzinda kwa miyezi yosachepera 6 chifukwa nthawi zambiri mumafunika kutsatira dokotala pambuyo pa BMT.
Q.
Ndani angapindule ndi kuikidwa magazi ndi mafuta a m'mafupa (BMT)?

A.
Matenda otsatirawa ndi omwe amafala kwambiri poika magazi kapena mafuta a m'mafupa:

- Khansa ya m'magazi

- Kuchepa kwa magazi m'thupi kwambiri

- Lymphoma

- Matenda a myeloma ambiri

- Matenda a kusowa kwa chitetezo chamthupi
Q.
Kodi chithandizo cha CAR-T n'chiyani?

A.
Chithandizo cha maselo a Chimeric antigen receptor T (CAR-T) ndi njira yatsopano yochizira khansa zosiyanasiyana. Cholinga chake ndikuchotsa maselo a T a wodwalayo ndikuwapatsa majini kuti atulutse chimeric antigen receptor (CAR) yomwe imazindikira antigen yokhudzana ndi chotupa (TAA). Zotsatira zake, maselo a T omwe amatuluka m'thupi la wodwalayo akabwezeretsedwanso m'thupi, amalimbana ndi maselo a chotupa omwe amatuluka m'thupi la wodwalayo.
Q.
Ndi odwala ati omwe amapindula ndi CAR-T?

A.
Kuyesa kwa CAR-T ndi kwa odwala omwe ali ndi B-cell acute lymphoblastic leukemia (B-ALL), B-cell lymphoma ndi multiple myeloma omwe abwereranso kapena asiya kugwiritsa ntchito chemotherapy.
Q.
Kodi tiyenera kukhala m'chipatala nthawi yayitali bwanji chifukwa cha CAR-T?

A.

Kuyesa kwa CAR-T kumatenga pafupifupi milungu 6-8, kutengera momwe wodwala aliyense alili.
Q.
Kodi njira yochizira CAR-T ndi yotani?

A.
Q.
Kodi mwachita CAR-T kangati?

A.
Kuyambira mu 2015, tamaliza mayeso pafupifupi 300 a CAR-T a B-ALL yobwereranso m'thupi, B-cell lymphoma ndi multiple myeloma ndipo zotsatira zake zinali zabwino kwambiri. Tinafotokoza mwachidule milandu 51 yoyamba ndipo tinaifalitsa mu Journal of Leukemia mu 2017.
Q.
Kodi chiŵerengero chanu cha kupambana mu CAR-T ndi chotani?

A.
Chiwerengero chonse cha kukhululukidwa kwathunthu chinali choposa 90%.
Q.
Kodi ubwino wochita opaleshoni ya mafupa (BMT) pambuyo pa CAR-T ndi wotani?

A.
Ngakhale kuti chiŵerengero cha kuchira kwathunthu (CR) cha chithandizo cha CAR-T chili chokwera, pali chiopsezo chobwereranso. Kafukufuku wasonyeza kuti kulumikiza BMT pambuyo pa CAR-T ndi B-ALL kungapangitse kuti chiwerengero cha kuchira chiwonjezeke.
Q.
Kodi ndingapeze bwanji nthawi yokumana ndi munthu wina?

A.
Mukhoza kupeza nthawi yokumana ndi anthu kudzera mwa oimira dipatimenti yathu yapadziko lonse.
Q.
Ndi zikalata ziti zomwe ndiyenera kubweretsa?

A.
Ndikofunikira kwambiri kuti mukamayenda mukhale ndi zikalata zonse zofunikira kuphatikizapo makope olembedwa a malipoti onse azachipatala, malipoti a matenda kuphatikizapo magalasi ndi ma paraffin blocks omwe adzafunika kuti muwunikenso, zotsatira za kujambula za CT, MRI, PET-CT scan, magazi, immune histochemistry, mayeso a majini, zotsatira za chromosome ngati zilipo.
Q.
Ndani adzayang'anira nthawi yanga yokumana ndi dokotala komanso nthawi yanga ndili kuchipatala?

A.
Gulu lathu lapadziko lonse lapansi lidzasungitsa nthawi yokumana ndi dokotala ndikukonza nthawi yoti mudzabwere kudzakuchezerani mukakhala kuchipatala.
Q.
Kodi njira yoti odwala apemphe uphungu kwa dokotala ndi yotani?

A.
Cholinga cha ogwira ntchito ku International Centre ndi kupereka chithandizo chosavuta komanso chopangidwa mwapadera kwa odwala athu apadziko lonse lapansi. Antchito athu adzakhalapo kuti athandize odwala onse pamlingo uliwonse wa chisamaliro chawo.
Q.
Kodi ndingapeze lipoti la mlandu wanga nditalandira chithandizo?

A.
Inde, tikalandira chithandizo, tidzamasulira lipoti la mlandu wanu ndikukupatsani lipoti la mlandu wanu mu Chingerezi ndi Chitchaina kuti muthe kubweza kudziko lanu.
Q.
Kodi wina angandithandize kupita ku eyapoti ndikabwerera kunyumba nditalandira chithandizo?

A.
Inde, ogwira ntchito ku International Center athu adzasungitsa galimotoyo ndi kukuthandizani kuyika katundu wanu mgalimoto ndikukutengerani ku eyapoti.