Nkhani
Chithandizo cha BIOOCUS Medical Group cha Dual CD19/BCMA CAR-T Chimapereka Zotsatira Zabwino mu Refractory Myasthenia Gravis: Ulendo wa Wodwala Wachinyamata
Wodwala waku Australia Wapeza Chiyankho Chodabwitsa Kwambiri Poyambirira ndi Chithandizo cha BIOOCUS Medical Group cha Dual CD19/CD20 CAR-T cha DLBCL Yobwerera M'mbuyo
Kufunika Kotsatira ndi Kufufuza Nthawi Zonse Pambuyo Poika Maselo a Hematopoietic Stem
Kutsatira pambuyo poika maselo oyambira m'thupi ndikofunikira kwambiri kwa odwala omwe amaika maselo oyambira m'magazi (HSCT). Kuyezetsa pafupipafupi kumathandiza kuzindikira mavuto monga matenda, matenda a graft-versus-host (GVHD), komanso kubwereranso, zomwe zimathandiza kuti munthu alowe mwachangu komanso kuti zinthu ziyende bwino.
Chithandizo cha CAR-T Chathetsa Kunenedweratu Koyipa mu Lymphoma Yapamwamba ya B-Cell
Kafukufuku watsopano akuwonetsa kuti chithandizo cha CAR-T chingathandize odwala omwe ali ndi B-cell lymphoma yapamwamba (HGBL), mtundu wa lymphoma yayikulu ya B-cell, ngakhale m'mizere yotsatira ya chithandizo, zomwe zikupereka chiyembekezo chatsopano cha milandu yovutayi.
Kuchiza Koyambirira ndi Chithandizo cha CAR-T cha Lymphoma Yaikulu ya B-Cell Kukuwonetsa Zotsatira Zabwino
Kafukufuku woyerekeza chithandizo cha CAR-T choyambirira ndi chakumapeto kwa odwala akuluakulu a B-cell lymphoma akuwonetsa kuti chithandizo choyambirira chingapereke chiwongola dzanja chabwino cha kupulumuka komanso zotsatirapo zochepa, zomwe zimathandiza kuti chigwiritsidwe ntchito ngati chithandizo chachiwiri.
Chithandizo cha CAR-T Chimasonyeza Chitetezo ndi Kuchita Bwino kwa Odwala Khansa Omwe Ali ndi Matenda Odziteteza Kuthupi Kapena Otupa
Kafukufuku waposachedwapa wofalitsidwa mu Lancet Rheumatology zikusonyeza kuti chithandizo cha maselo a CAR-T ndi chotetezeka komanso chothandiza pochiza lymphoma ndi odwala ambiri a myeloma omwe ali ndi matenda odziteteza okha kapena otupa, zomwe zikupereka umboni wodalirika woti chimagwiritsidwa ntchito kwambiri.
Kuzindikira Kopambana kwa Mitundu Ya Majini ya B-ALL Ya Akuluakulu
Ndemanga yonse mu Magazi ikuwonetsa kupita patsogolo kwaposachedwa pakumvetsetsa mitundu yosiyanasiyana ya majini a B-cell akuluakulu Acute Lymphoblastic Leukemia (B-ALL). Kafukufukuyu akufufuza kusiyana kwa zamoyo, zotsatira zachipatala, ndi kufunika kwa mankhwala olondola pakukweza zotsatira za odwala.
Kafukufuku Wotsogola Akutsimikizira Chitetezo ndi Kugwira Ntchito kwa Chithandizo cha CD19/CD20 CAR-T pa r/r B-NHL
Kuyesa kwa magawo ambiri ku China kwawonetsa chitetezo ndi kugwira ntchito bwino kwa prizlon-cel, chithandizo cha CD19/CD20 CAR-T chomwe chimayendetsedwa ndi magulu awiri, kupereka chiyembekezo chatsopano kwa odwala omwe ali ndi lymphoma ya B-cell non-Hodgkin (r/r B-NHL) yobwereranso/yosasinthika.
Akatswiri Atsopano Olemba Zamoyo Amalosera Zotsatira za Chithandizo cha CAR-T mu Chithandizo cha Multiple Myeloma
Kafukufuku waposachedwapa wofalitsidwa mu Magazi imazindikira kuchuluka kwa BCMA (sBCMA) yosungunuka komanso kuchuluka kwa chotupa cha metabolic (MTV) ngati zizindikiro zomwe zingatheke poneneratu zotsatira za chithandizo cha CAR-T mwa odwala omwe abwereranso m'thupi komanso omwe ali ndi matenda a myeloma yambiri (RRMM), zomwe zimapangitsa njira zothandizira payekha.
Chithandizo cha CAR-T: Tsogolo Lodalirika la Matenda a T-Cell
Chithandizo cha CAR-T, chomwe poyamba chinali chitukuko cha khansa ya m'maselo a B, chikuwonetsa chiyembekezo pochiza khansa ya m'maselo a T ndi khansa ya m'maselo a T (T-ALL). Chithandizo chosinthikachi chikukumana ndi zovuta zapadera koma mayeso azachipatala aposachedwapa amapereka chiyembekezo cha njira zatsopano zochiritsira khansa ya m'maselo a T.
Kafukufuku Wotsogola Wofalitsidwa mu Blood: Nanobody-Based CD7 CAR-T Therapy for Acute Myeloid Leukemia
Gulu la Zachipatala la Lu Daopei lapita patsogolo kwambiri pochiza matenda a Acute Myeloid Leukemia (AML) ndi kafukufuku wawo wokhudza chithandizo cha CD7 CAR-T chochokera ku nanobody, chofalitsidwa mu magazini yotchuka. Magazi.
Mankhwala Oletsa Menin: Chithandizo Chodabwitsa cha Khansa ya Myeloid Yoopsa
Kupita patsogolo kwaposachedwa kwa mankhwala oletsa matenda a Menin kumapereka njira zabwino zochiritsira matenda a khansa ya m'magazi (AML), kumayang'ana kwambiri kusintha kwa majini ndikupereka chiyembekezo chatsopano kwa odwala omwe ali ndi vuto lalikulu.