Nkhani Zamakampani
Chithandizo cha CAR-T Chathetsa Kunenedweratu Koyipa mu Lymphoma Yapamwamba ya B-Cell
Kafukufuku watsopano akuwonetsa kuti chithandizo cha CAR-T chingathandize odwala omwe ali ndi B-cell lymphoma yapamwamba (HGBL), mtundu wa lymphoma yayikulu ya B-cell, ngakhale m'mizere yotsatira ya chithandizo, zomwe zikupereka chiyembekezo chatsopano cha milandu yovutayi.
Kuthana ndi Mavuto Anthawi Yaitali a Chithandizo cha CAR-T: Chidziwitso Chochokera ku Khansa Yachilengedwe
Kafukufuku waposachedwapa wofalitsidwa mu Khansa ya Chilengedwe ikuwonetsa zovuta zomwe zimachitika nthawi yayitali chifukwa cha chithandizo cha maselo a CAR-T, ikuyang'ana kwambiri zoopsa za matenda ndi khansa yachiwiri, ndipo imapereka njira zowongolera zotsatira za odwala.
Kuthana ndi Mavuto mu Chithandizo cha CAR-T cha Khansa ya Magazi ya T-Cell
Ngakhale chithandizo cha CAR-T chasintha kwambiri chithandizo cha khansa ya maselo a B, mavuto akuluakulu adakalipo pochiza khansa ya maselo a T. Ndemanga yaposachedwa ikufotokoza zovuta za chithandizo cha CAR-T mu khansa ya maselo a T komanso njira zothetsera mavutowa.
Kumvetsetsa Thalassemia: Buku Lophunzitsira la Alpha ndi Beta
Thalassemia ndi matenda angapo. Bukuli likufotokoza za alpha ndi beta thalassemia, zomwe zimayambitsa, zizindikiro, komanso njira zaposachedwa zochiritsira zomwe zikupezeka ku BIOOCUS International Medical Center.
Chithandizo cha Maselo a NK Chophatikizidwa ndi Katemera wa DC Chikuwonetsa Kusintha Kwakukulu mu Khansa ya Chiwindi Yochedwa
Kupita patsogolo kwa chithandizo cha khansa ya chiwindi yowonjezereka kwaonekera kudzera mu kuphatikiza kwatsopano kwa mankhwala a NK cell, katemera wa DC, ndi Nivolumab. Chithandizo chophatikizana ichi cha immunotherapy chakhala chopambana kwambiri, zomwe zapangitsa kuti chotupa chichepe kwambiri komanso kuti chiwindi chigwire bwino ntchito m'masabata asanu ndi limodzi okha kwa wodwala yemwe ali ndi khansa ya chiwindi yomwe yatsala pang'ono kutha.
Chithandizo Chatsopano cha Majini Chathandiza Kuchiza Matenda a Sickle Cell ndi Thalassemia
Pa nkhani yoyamba yachipatala, wodwala wazaka 21 anapambana bwino mavuto a thalassemia kudzera mu njira yapamwamba yopangira majini ya CRISPR. Njira yatsopanoyi ndi yofunika kwambiri pochiza matenda oopsa a magazi monga matenda a sickle cell (SCD) ndi thalassemia.
Kusamalira Zotsatirapo Zake za Chithandizo cha Maselo a CAR-T: Mfundo Zofunika Kuchokera ku Kafukufuku Waposachedwapa
Nkhaniyi ikufotokoza za kafukufuku waposachedwa wokhudza kuthana ndi poizoni wa mankhwala a maselo a CAR-T a B-cell lymphomas. Kafukufukuyu akugogomezera njira zothetsera mavuto wamba monga cytokine release syndrome (CRS) ndi neurotoxicity (ICANS), kuonetsetsa kuti chithandizochi chikugwiritsidwa ntchito bwino.
Kugwira Ntchito Kwanthawi Yaitali kwa Chithandizo cha CD19 CAR T-Cell Pochiza Matenda a Leukemia Obwerera M'mbuyo/Osasinthika
Kafukufuku wodziwika bwino akuwonetsa kupambana kwa nthawi yayitali kwa chithandizo cha maselo a CD19 CAR T pochiza odwala omwe ali ndi khansa ya m'magazi yobwereranso/yosakhazikika (ALL) pambuyo poika maselo oyambira a hematopoietic hematopoietic, zomwe zikupereka chiyembekezo chatsopano mu hematology.
Kupita Patsogolo kwa Maselo Opha Zachilengedwe (NK) Kwa Zaka Zoposa 50
Kwa zaka makumi asanu zapitazi, kafukufuku wokhudza maselo a Natural Killer (NK) wasintha kwambiri kumvetsetsa kwathu chitetezo chamthupi, zomwe zatipatsa njira zatsopano zodalirika zochiritsira khansa ndi mavairasi.
Kupita Patsogolo kwa Matenda Odziteteza ku Matenda a Ana: Chithandizo cha Maselo a CAR-T Chimachiritsa Wodwala wa Lupus
Kafukufuku woyambirira ku Chipatala cha Erlangen University Hospital adathandiza bwino mtsikana wazaka 16 yemwe anali ndi matenda oopsa a systemic lupus erythematosus (SLE) pogwiritsa ntchito CAR-T cell therapy. Ichi ndi chiyambi choyamba cha kugwiritsa ntchito mankhwalawa pa ana a lupus, zomwe zikupereka chiyembekezo chatsopano kwa ana omwe ali ndi matenda odziteteza okha.
Kupititsa patsogolo Kugwira Ntchito kwa PROTAC: Kafukufuku Woyambitsa Chidwi
Kafukufuku waposachedwa mu Nature Communications akuwonetsa mfundo zazikulu za njira zolumikizirana zomwe zimathandizira kuchepetsa mphamvu ya kuwonongeka kwa mapuloteni pogwiritsa ntchito PROTACs. Kupeza kumeneku kungathandize kupeza njira yothandiza kwambiri yochizira khansa ndi matenda ena.
Kulimbikitsa Thanzi ndi Kuchira: Chisamaliro cha Tsiku ndi Tsiku cha Odwala Khansa ya M'magazi
Kuonetsetsa kuti odwala a khansa ya m'magazi akupeza chithandizo chotetezeka komanso chomasuka kumafuna chisamaliro chapadera cha tsiku ndi tsiku, kuphatikizapo ukhondo wa chilengedwe, ukhondo waumwini, zakudya zoyenera, komanso kuchita masewera olimbitsa thupi oyenera. Bukuli limapereka malangizo ofunikira kuti munthu azitha kuchira bwino tsiku ndi tsiku.