Nūhou ʻOihana
Ua lanakila ka CAR-T Therapy i ka Prognosis maikaʻi ʻole ma ka Lymphoma B-Cell kiʻekiʻe
Ua hōʻike ʻia kahi noiʻi hou e hiki i ka lāʻau lapaʻau CAR-T ke hoʻomaikaʻi i ka prognosis no nā poʻe maʻi me ka lymphoma B-cell kiʻekiʻe (HGBL), kahi ʻano o ka lymphoma B-cell nui, ʻoiai ma nā laina lapaʻau ma hope, e hāʻawi ana i ka manaʻolana hou no kēia mau hihia paʻakikī.
Ka Hoʻokele ʻana i nā Pilikia Lōʻihi o ka CAR-T Therapy: Nā ʻIke mai ke Kanesa Kūlohelohe
Ua paʻi ʻia kahi noiʻi hou i loko o Ka maʻi ʻaʻai kūlohelohe hōʻike i nā pilikia lōʻihi o ka lāʻau lapaʻau CAR-T cell, e kālele ana i nā pilikia o nā maʻi a me nā maʻi malignancies lua, a hāʻawi i nā hoʻolālā e hoʻomaikaʻi i nā hopena o ka mea maʻi.
Ke lanakila nei i nā pilikia ma ka CAR-T Therapy no nā maʻi ʻaʻai koko T-Cell
ʻOiai ua hoʻololi ka lāʻau lapaʻau CAR-T i ka mālama ʻana i nā maʻi ʻaʻai B-cell, ke mau nei nā pilikia koʻikoʻi i ka mālama ʻana i nā maʻi ʻaʻai T-cell. Ke nānā nei kahi loiloi hou i nā paʻakikī o ka lāʻau lapaʻau CAR-T i nā maʻi ʻaʻai koko T-cell a me nā hopena kūpono e lanakila ai i kēia mau pilikia.
Ke Hoʻomaopopo nei i ka Thalassemia: He Alakaʻi Piha i nā ʻAno Alpha a me Beta
ʻOi aku ma mua o hoʻokahi maʻi ka Thalassemia. Ke nānā nei kēia alakaʻi i ka alpha a me ka beta thalassemia, ko lākou mau kumu, nā hōʻailona, a me nā koho lapaʻau hou loa i loaʻa ma BIOOCUS International Medical Center.
Hōʻike ka NK Cell Therapy i hui pū ʻia me ka DC Vaccine i ka hoʻomaikaʻi nui ʻana i ka maʻi kanesa o ke akepaʻa hope loa
Ua puka mai kahi holomua i ka mālama ʻana i ka maʻi kanesa akepaʻa holomua ma o ka hui pū ʻana o ka lāʻau lapaʻau NK cell, ka lāʻau pale DC, a me Nivolumab. Ua hōʻike kēia immunotherapy i hui pū ʻia i ka holomua kupaianaha, e alakaʻi ana i ka hōʻemi nui ʻana o ka puʻupuʻu a me ka hoʻomaikaʻi ʻana i ka hana o ke akepaʻa i loko o ʻeono pule wale nō no kahi mea maʻi me ka hepatocellular carcinoma hope loa.
Hoʻokō ka Therapy Gene Hou i kahi holomua i ka mālama ʻana i ka maʻi Sickle Cell a me Thalassemia
Ma kahi hihia lapaʻau paionia, ua lanakila maikaʻi kahi maʻi 21 makahiki i nā pilikia o ka thalassemia ma o kahi lāʻau lapaʻau gene CRISPR holomua. Hōʻailona kēia ʻano hana hou i kahi hanana koʻikoʻi i ka mālama ʻana i nā maʻi koko koʻikoʻi e like me ka maʻi cell sickle (SCD) a me ka thalassemia.
Ke Kaʻina Hana ʻana i nā Hopena ʻAoʻao o ka CAR-T Cell Therapy: Nā ʻIke Koʻikoʻi mai ka Noiʻi Hou
Hōʻike kēia ʻatikala nūhou i ka noiʻi hou e pili ana i ka hoʻokele ʻana i nā ʻawaʻawa o ka lāʻau lapaʻau CAR-T no nā lymphomas B-cell. Hoʻoikaika ka haʻawina i nā hoʻolālā e lawelawe i nā hopena ʻaoʻao maʻamau e like me ka cytokine release syndrome (CRS) a me ka neurotoxicity (ICANS), e hōʻoiaʻiʻo ana i ka hoʻohana palekana ʻana i kēia lāʻau lapaʻau hou.
Ka hopena lōʻihi o ka CD19 CAR T-Cell Therapy i ka mālama ʻana i ka Relapsed/Refractory Acute Lymphoblastic Leukemia
Hōʻike kahi haʻawina hou i ka holomua lōʻihi o ka lāʻau lapaʻau CD19 CAR T-cell i ka mālama ʻana i nā maʻi me ka relapsed/refractory acute lymphoblastic leukemia (ALL) ma hope o ka hoʻoili ʻana o nā cell stem hematopoietic allogeneic, e hāʻawi ana i ka manaʻolana hou i ka hematology.
Nā Holomua Hou i nā Pūnaewele Killer Kūlohelohe (NK) ma luna o 50 mau makahiki
I nā makahiki he ʻelima i hala iho nei, ua hoʻololi ka noiʻi ʻana i nā pūnaewele Natural Killer (NK) i ko mākou ʻike i ka pale kūlohelohe, e hāʻawi ana i nā ala hou no ka maʻi kanesa a me nā lāʻau lapaʻau viral.
Ka holomua i ka maʻi Autoimmune Pediatric: Hoʻōla ka CAR-T Cell Therapy i ka mea maʻi Lupus
Ua mālama pono ʻia kahi kaikamahine 16 makahiki me ka systemic lupus erythematosus (SLE) koʻikoʻi ma kahi noiʻi paionia ma ka Halemai o ke Kulanui ʻo Erlangen me ka hoʻohana ʻana i ka lāʻau lapaʻau CAR-T cell. ʻO kēia ka hoʻohana mua ʻana o kēia lāʻau lapaʻau no ka lupus pediatric, e hāʻawi ana i ka manaʻolana hou no nā keiki me nā maʻi autoimmune.
Ka Hoʻoikaika ʻana i ka Pono o PROTAC: He Haʻawina Hoʻomaka Hou
Ua hōʻike ʻia kahi noiʻi hou ma Nature Communications i nā ʻike koʻikoʻi i loko o nā ala hōʻailona kūloko e hoʻololi i ka pono o ka hoʻohaʻahaʻa protein i kuhikuhi ʻia me ka hoʻohana ʻana i nā PROTAC. Hiki i kēia ʻike ke hoʻomākaukau i ke ala no nā lāʻau lapaʻau ʻoi aku ka maikaʻi no ka maʻi kanesa a me nā maʻi ʻē aʻe.
Ke Paipai nei i ke Ola Kino a me ka Hoʻōla: Mālama i kēlā me kēia lā no nā maʻi Leukemia
ʻO ka hōʻoia ʻana i kahi ʻike lapaʻau palekana a ʻoluʻolu hoʻi no nā maʻi leukemia e pili ana i ka mālama pono ʻana i kēlā me kēia lā, me ka hoʻomaʻemaʻe ʻana i ke kaiapuni, ka hoʻomaʻemaʻe pilikino, ka meaʻai, a me ka hoʻoikaika kino kūpono. Hāʻawi kēia alakaʻi i nā ʻōlelo aʻoaʻo koʻikoʻi no ka mālama pono ʻana i kēlā me kēia lā e kākoʻo i ka hoʻōla ʻana.