Ke Hoʻomaopopo nei i ka Thalassemia: He Alakaʻi Piha i nā ʻAno Alpha a me Beta

ʻO ka Thalassemia, kahi maʻi koko genetic, he mea nui ia e pili ana i nā miliona o ka honua, ʻoi aku hoʻi ma nā wahi e like me ke Kaiwaenahonua, ʻAsia Hikina Hema, a me nā ʻāpana o Kina. ʻOiai ua kamaʻāina ka hapa nui o ka poʻe me ka beta-thalassemia, hele mai ka maʻi i ʻelua ʻano nui: alpha-thalassemia a me beta-thalassemia. Loaʻa i nā mea ʻelua nā kumu a me nā hōʻike like ʻole, a ʻo ka hoʻomaopopo ʻana i kēia mau ʻokoʻa he mea nui ia no ka ʻike pono ʻana a me ka mālama ʻana.

He aha ka Thalassemia?

He maʻi koko hoʻoilina ka Thalassemia kahi e hana ai ke kino i kahi ʻano hemoglobin ʻano ʻē, e hopena ana i ka luku nui ʻia ʻana o nā hunaola koko ʻulaʻula a alakaʻi i ka anemia. ʻO nā ʻano nui ʻelua, ʻo ka alpha-thalassemia a me ka beta-thalassemia, ua hoʻokumu ʻia e nā mutations i loko o nā genes nāna e hana i ka protein hemoglobin.

Ka laha ʻana o ka Thalassemia

ʻOiai ua ʻoi aku ka maʻamau o ka thalassemia ma nā ʻāina Mediterranean i ka wā mua, ua laha ka maʻi i nā wahi like ʻole. Ma Kina, no ka laʻana, ua hōʻike nā haʻawina he hapa nui o ka heluna kanaka ma nā wahi e like me Guangdong e lawe ana i nā ʻano genetic no ka thalassemia, me kekahi mau haʻawina e hōʻike ana i ka nui o ka mea lawe a hiki i ka 11%.

ʻO Alpha a me Beta Thalassemia: He aha ka ʻokoʻa?

ʻOiai ʻo nā ʻano ʻelua e hoʻopilikia i ka hana hemoglobin, ʻokoʻa nā genes i pili a me nā hōʻike maʻi:

1. ʻAlapha-Thalassemia: ʻO kēia ʻano e pili ana i ka hemahema o nā kaulahao alpha-globin o ka hemoglobin. Inā hoʻoilina kekahi kanaka i hoʻokahi gene ʻano ʻē, loaʻa paha iā lākou kahi ʻano ʻoluʻolu i ʻike ʻia he "silent carrier" me ka ʻole o nā hōʻailona. Me ʻelua mau gene ʻano ʻē, hiki i nā maʻi ke loaʻa ka alpha-thalassemia major, hiki ke hoʻoulu i ka anemia waena a koʻikoʻi. Inā hoʻoilina ke keiki i ʻehā mau gene alpha hemahema, hiki i ka hopena ke make, e alakaʻi pinepine ana i ka hānau keiki make a i ʻole ka make ma hope koke iho o ka hānau ʻana.

2. ʻO ka Beta-Thalassemia: Ua like ia me ka alpha-thalassemia akā pili i nā kaulahao beta-globin, ua māhele pinepine ʻia ka beta-thalassemia i ʻekolu mau māhele: liʻiliʻi, waena, a me ke nui. I nā hihia koʻikoʻi, i ʻike ʻia ʻo beta-thalassemia nui, hōʻike pinepine nā keiki i nā hōʻailona i loko o ka makahiki mua o ke ola, me ka hiki ʻole ke ulu pono, ka hānai maikaʻi ʻole, a me nā lohi o ka ulu ʻana. Me ka ʻole o ka mālama ʻana, hiki i kēia ʻano ke alakaʻi i nā pilikia koʻikoʻi, me ka hōʻino ʻana o nā kino.

Nā hōʻailona o ka Thalassemia

• ʻAlapha-Thalassemia: Hiki i nā maʻi me ʻelua mau genes ʻano ʻē ke loaʻa i ka anemia iki me nā hōʻailona e like me ka luhi, ka mae, a me ka hoʻonui iki ʻana o ka spleen a me ke ake. Me ʻekolu mau genes kīnā (maʻi HbH), hiki i nā kānaka ke loaʻa i ka anemia ʻoi aku ka koʻikoʻi, ʻoiai ʻo ka poʻe me ʻehā mau genes kīnā e kū nei i nā pilikia koʻikoʻi a hoʻoweliweli i ke ola i ka wā hāpai a i ʻole ma hope koke o ka hānau ʻana.

• ʻO ka Beta-Thalassemia: ʻO ka Beta-thalassemia major ka mea i hōʻailona ʻia e ka anemia koʻikoʻi e hoʻomaka ana ma kahi o 3-6 mau mahina o ka makahiki, me nā hōʻailona e like me ka ʻili keʻokeʻo, ka luhi, ke akepaʻa a me ka spleen i hoʻonui ʻia, a me ka ulu maikaʻi ʻole. Hiki nō hoʻi ke ulu aʻe nā "thalassemia facies" maʻamau - nā iwi papālina i ʻike nui ʻia a me ka lae nui.

Nā Koho Lapaʻau no ka Thalassemia

Ma BIOOCUS International Medical Center, hāʻawi mākou i nā lāʻau lapaʻau hou loa no ka thalassemia, me:

• Nā Hoʻoili Koko: He mea nui nā hoʻoili koko mau no ka mālama ʻana i nā ʻano thalassemia koʻikoʻi. Kōkua kēia i ka mālama ʻana i nā pae hemoglobin a hōʻoluʻolu i nā hōʻailona.

• Ka Lapaʻau Chelation Hao: Ma muli o ka hoʻoili pinepine ʻana i ka hao hiki ke alakaʻi i ka nui o ka hao, kahi e hōʻino ai i nā kino koʻikoʻi, hoʻohana ʻia ka chelation therapy e wehe i ka hao keu mai ke kino.

• Hoʻoili Kelepona Kumu: No nā poʻe maʻi kūpono, hāʻawi nā hoʻoili cell stem i ka hiki ke ho'ōla mau loa, ʻoiai hoʻi i ke ʻano o ka beta-thalassemia major.

• Hoʻōla Gene: Aia nō kēia ʻano hana hou i ke kahua noiʻi akā he manaʻolana nui kona no ka hāʻawi ʻana i nā hopena lōʻihi i nā poʻe maʻi thalassemia.

Kāohi a me ka Nānā ʻana

ʻOiai he maʻi hoʻoilina ka thalassemia, hiki i ka nānā ʻana ma mua o ka hāpai ʻana ke kōkua i nā mākua e hoʻomaopopo i ka pilikia o ka hoʻoili ʻana i ka maʻi. Loaʻa nā hoʻokolohua nānā mea lawe no ka alpha a me ka beta thalassemia a hiki ke hōʻemi nui i ka hanana o ka thalassemia i nā hanauna e hiki mai ana.

Ma BIOOCUS International Medical Center, paipai ikaika mākou i ka nānā ʻana ma mua o ka male ʻana a me ka prenatal no ka thalassemia, ʻoi aku hoʻi no nā kāne a me nā wahine mai nā wahi pilikia nui, i mea e pale ai i ka laha ʻana o kēia maʻi hiki ke hoʻonāwaliwali.

No ke aha e koho ai iā BIOOCUS?

Ua hoʻolaʻa ʻia ʻo BIOOCUS International Medical Center i ka hāʻawi ʻana i nā koho lapaʻau holomua no nā poʻe maʻi thalassemia. Ua kūpaʻa kā mākou hui loea o nā hematologists, oncologists, a me nā loea i nā maʻi genetic i ka hāʻawi ʻana i ka mālama pilikino a me nā therapies hou loa e hoʻokele a mālama pono i ka thalassemia.

Aia mākou ma ke alo o ka noiʻi lapaʻau i ka mālama ʻana i ka thalassemia, a ʻo kā mākou ʻano mālama piha e hōʻoiaʻiʻo ana e loaʻa i nā mea maʻi ʻaʻole wale ka lāʻau lapaʻau maikaʻi loa akā ke kākoʻo naʻau a me ka noʻonoʻo hoʻi i kā lākou huakaʻi.