Amakuru y'inganda
Ubuvuzi bwa CAR-T bwatsinze ikibazo cyo kurwara Lymphoma yo mu bwoko bwa B-cell classified nabi
Ubushakashatsi bushya bwerekana ko ubuvuzi bwa CAR-T bushobora kunoza imiterere y’indwara ku barwayi ba lymphoma yo mu rwego rwo hejuru ya B (HGBL), ubwoko bwa lymphoma nini ya B, ndetse no mu nzira zo kuvurwa nyuma, bigatanga icyizere gishya kuri izi ndwara zikomeye.
Gukemura ibibazo by'igihe kirekire by'ubuvuzi bwa CAR-T: Ibisobanuro bivuye kuri Kanseri y'umwimerere
Ubushakashatsi buherutse gusohoka muri Kanseri y'ibidukikije igaragaza ingorane z'igihe kirekire zo kuvura selile za CAR-T, yibanda ku ngaruka zo kwandura no kurwara kanseri y'inyongera, kandi itanga ingamba zo kunoza umusaruro w'abarwayi.
Gutsinda Imbogamizi mu Buvuzi bwa CAR-T ku Kanseri y'amaraso ya T-cell
Nubwo ubuvuzi bwa CAR-T bwahinduye uburyo bwo kuvura kanseri ya B-cell, haracyari imbogamizi zikomeye mu kuvura kanseri ya T-cell. Isuzuma riherutse gukorwa rigaragaza ingorane zo kuvura CAR-T muri kanseri ya T-cell mu maraso ndetse n'ibisubizo bishoboka byo gutsinda izi mbogamizi.
Gusobanukirwa Thalassemia: Ubuyobozi Burambuye ku Miterere ya Alpha na Beta
Thalassemia ni indwara zirenze imwe. Iyi nyandiko isuzuma indwara ya alpha na beta thalassemia, impamvu zayo, ibimenyetso byayo, ndetse n'uburyo bushya bwo kuvura buboneka muri BIOOCUS International Medical Center.
Uburyo bwo kuvura kanseri y'umwijima bwa NK buhujwe n'urukingo rwa DC bwagaragaje iterambere rikomeye muri kanseri y'umwijima iri mu cyiciro cya nyuma
Iterambere mu kuvura kanseri y'umwijima ryagaragaye binyuze mu buryo bushya bwo kuvura kanseri ya NK, urukingo rwa DC, na Nivolumab. Ubu buryo bwo kuvura indwara z'umubiri bwagaragaje umusaruro utangaje, byatumye ikibyimba kigabanuka cyane kandi imikorere y'umwijima irushaho kuba myiza mu byumweru bitandatu gusa ku murwayi urwaye kanseri y'umwijima iri mu cyiciro cya nyuma.
Uburyo bushya bwo kuvura ingirabuzima fatizo bwageze ku ntambwe ishimishije mu kuvura indwara ya Sickle Cell na Thalassemia
Mu rubanza rw’ibanze rw’ubuvuzi, umurwayi w’imyaka 21 yatsinze neza ibibazo bya thalassemia binyuze mu buvuzi bugezweho bushingiye kuri CRISPR bushingiye ku ngirabuzima fatizo. Ubu buryo bushya bugaragaza intambwe ikomeye mu kuvura indwara zikomeye z’amaraso nka sickle cell disease (SCD) na thalassemia.
Gucunga ingaruka mbi zo kuvura uturemangingo twa CAR-T: Ibisobanuro by'ingenzi byavuye mu bushakashatsi buherutse gukorwa
Iyi nkuru y’amakuru igaragaza ubushakashatsi buherutse gukorwa ku kuvura uburozi bwa CAR-T cell therapy kuri lymphomas za B-cell. Ubu bushakashatsi bushimangira ingamba zo guhangana n’ingaruka zisanzwe nka cytokine release syndrome (CRS) na neurotoxicity (ICANS), hagamijwe ko ubu buryo bw’ubuvuzi bukoreshwa neza.
Ingufu z'igihe kirekire zo kuvura CD19 CAR T-cells mu kuvura Leukemia yo mu bwoko bwa Acute Lymphoblastic Leukemia yasubiwemo/yasubiwemo
Ubushakashatsi bw’ingenzi bwagaragaje ko uburyo CD19 CAR T-selile zavuwe bwagize icyo bugeraho mu kuvura abarwayi bafite leukemia ya lymphoblastic yasubiwemo/yasubiwemo nyuma yo gutera uturemangingo tw’amaraso twa allogeneic hematopoietic, butanga icyizere gishya mu bijyanye n’amaraso.
Iterambere ry'Ingingo z'Ubwicanyi Busanzwe (NK) mu myaka irenga 50 ishize
Mu myaka mirongo itanu ishize, ubushakashatsi ku turemangingo tw’umubiri twica ubudahangarwa (NK) bwahinduye imyumvire yacu ku budahangarwa bw’umubiri, butanga uburyo bushya bwiza bwo kuvura kanseri n’udukoko.
Iterambere mu ndwara z’ubwiyongere bw’umubiri ku bana: Ubuvuzi bwa CAR-T Selire bwakijije umurwayi wa Lupus
Ubushakashatsi bwakozwe ku bitaro bya Kaminuza ya Erlangen bwavuje neza umukobwa w’imyaka 16 wari ufite indwara ikomeye ya lupus erythematosus (SLE) hakoreshejwe uburyo bwa CAR-T cell therapy. Ubu ni bwo buryo bwa mbere bwo kuvura lupus mu bana, butanga icyizere gishya ku bana bafite indwara ziterwa n’ubwiyongere bw’umubiri.
Kongera imikorere ya PROTAC: Inyigo Ifatika
Ubushakashatsi buherutse gukorwa muri Nature Communications bwagaragaje ibitekerezo by'ingenzi ku nzira z'ubuhanga mu gutanga ibimenyetso zihindura imikorere y'igabanuka rya poroteyine hifashishijwe PROTACs. Ubu buvumbuzi bushobora gutanga inzira yo kuvura kanseri n'izindi ndwara neza kurushaho.
Guteza imbere ubuzima no gukira: Kwita ku barwayi ba kanseri y'amaraso buri munsi
Kugira ngo abarwayi ba kanseri y'amaraso bavurwe neza kandi neza, bisaba kwita ku buzima bwabo bwa buri munsi, harimo isuku ku bidukikije, isuku y'umubiri, imirire myiza, n'imyitozo ngororamubiri ikwiye. Iyi nyandiko itanga inama z'ingenzi zo kwita ku buzima bwa buri munsi mu buryo bwiza kugira ngo bakire.