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Ibyiciro by'Ubuvuzi
Uburyo bwo kuvura bwagaragaye
Lymphoma nini ya B-cell lymphoma (DLBCL)-04

Lymphoma nini ya B-cell lymphoma (DLBCL)-04
Uburyo bwo kuvura indwara ya Myasthenia Gravis (MG) bwa CAR-T

Uburyo bwo kuvura indwara ya Myasthenia Gravis (MG) bwa CAR-T
Ubuvuzi bwa Virusi ya Oncolytic: Ubuvuzi bwa Kanseri bugezweho

Ubuvuzi bwa Virusi ya Oncolytic: Ubuvuzi bwa Kanseri bugezweho
Umuhungu urwaye kanseri y'amaraso ikabije (Acute lymphoblastic Leukemia)

Umuhungu urwaye kanseri y'amaraso ikabije (Acute lymphoblastic Leukemia)
Gutsinda Lymphoma nini ya B-cell ikwirakwira hakoreshejwe uburyo bwa Bioocus Dual CAR-T Therapy

Gutsinda Lymphoma nini ya B-cell ikwirakwira hakoreshejwe uburyo bwa Bioocus Dual CAR-T Therapy
Kurwanya kanseri y'umwijima hakoreshejwe uburyo bwa Bioocus GPC3 CAR-T Therapy

Kurwanya kanseri y'umwijima hakoreshejwe uburyo bwa Bioocus GPC3 CAR-T Therapy
Igisubizo gitangaje mu ndwara ya Myeloma nyinshi ya Refractory nyuma yo kuvura CAR-T cell therapy

Igisubizo gitangaje mu ndwara ya Myeloma nyinshi ya Refractory nyuma yo kuvura CAR-T cell therapy
Intsinzi ya Madhavan: Gutsinda Glioma yo mu bwonko hakoreshejwe Bioocus B7H3 CAR-T Therapy

Intsinzi ya Madhavan: Gutsinda Glioma yo mu bwonko hakoreshejwe Bioocus B7H3 CAR-T Therapy
Umuhungu muto w’umunyembaraga wo mu Burusiya arwana n’indwara ya neuroblastoma

Umuhungu muto w’umunyembaraga wo mu Burusiya arwana n’indwara ya neuroblastoma
Umugabo w’intwari ukomoka mu Buhinde arwana na kanseri y’igifu

Umugabo w’intwari ukomoka mu Buhinde arwana na kanseri y’igifu
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FUCASO: Ubuvuzi bwa BCMA CAR-T bugezweho bufite imikorere n'umutekano bidasanzwe

FUCASO ni uburyo bushya bwo kuvura CAR-T bushingiye kuri BCMA bukorwa na IASO BIO, butanga imikorere myiza n'umutekano ku ndwara ya myeloma nyinshi yasubiwemo cyangwa idashobora kuvura. Hamwe n'uburyo bwo gusubiza indwara ku buryo buhanitse, kugabanuka ku buryo burambye, no kugira umutekano ukomeye, FUCASO itanga icyizere gishya ku barwayi kandi ishyiraho amahame mashya mu kuvura CAR-T.

    Twandikire
    Ibisobanuro birambuye ku gicuruzwa
    Ibyiza by'ingenzi bya FUCASO
    Intsinzi mu buvuzi

    ibisobanuro birambuye by'igicuruzwa

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    FUCASO, yakozwe na Nanjing IASO Biotechnology, ni uburyo bushya bwo kuvura bwa CAR-T bwagenewe kwibasira antigen yo gukura kwa selile B (BCMA). Ubu buryo bugaragara kubera ubushobozi bwabwo budasanzwe mu buvuzi no mu mutekano, butanga icyizere gishya ku barwayi ba myeloma nyinshi yasubiwemo cyangwa idashobora kugaragara. Byemejwe n'Ikigo cy'Igihugu gishinzwe Ibikoresho by'Ubuvuzi (NMPA) ku ya 30 Kamena 2023, FUCASO imaze kugaragaza ko ikora neza cyane mu buvuzi.

    Ibyiza by'ingenzi bya FUCASO

    Igipimo cyo hejuru cy'abakira: FUCASO ifite igipimo rusange cyo gusubiza (ORR) cya 98.9% n'igipimo cyuzuye cyo gusubiza (CR) cya 82.4%, kiri hejuru cyane ugereranyije n'ubundi buryo bwo kuvura buhari.

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    Imbabazi zirambye: Abarwayi bavuwe na FUCASO bagaragaje igipimo cya 85.5% cy'amezi 12 cyo kubaho nta ndwara (Progression-Free Survival - PFS), bigaragaza ko bakize igihe kirekire kandi ubuzima bwabo bugakomeza kuba bwiza.

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    Umwirondoro w'umutekano: Kubera ko indwara ya Cytokine Release Syndrome (CRS) yo mu cyiciro cya ≥3 igaragara ku 1% gusa by'abarwayi kandi nta barwayi bagaragaye bafite indwara ya ICANS yo mu cyiciro cya ≥3, FUCASO itanga uburyo bwo kuvura bwizewe ugereranije n'ubundi buryo bwo kuvura bwa CAR-T.

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    Uburyo bwo Kugabanya Ikiguzi: Uburyo bwo kuvura bwa FUCASO buhendutse cyane ugereranyije n’ubundi buryo bukoreshwa muri Leta Zunze Ubumwe za Amerika, bigatuma ari uburyo bwiza ku barwayi benshi.

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    Kugera ku Isi: IASO BIO yashinze ikigo cy’ubuvuzi cyuzuye mu Bushinwa, gishobora gufasha abarwayi baturutse impande zose z’isi mu gutanga serivisi zihuriweho kuva ku bujyanama kugeza ku buvuzi nyuma yo kuvurwa.

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    Intsinzi mu buvuzi

    Umurwayi wa mbere wavuwe na FUCASO amaze imyaka itanu adafite kanseri, ikaba ari intambwe ikomeye ugereranije n'igihe cy'amezi 2.9 gusa cyo kubaho nta ndwara isanzwe. Ibi bigaragaza ubushobozi bwa FUCASO bwo guhindura uburyo bwo kuvura indwara ya myeloma nyinshi.

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