FUCASO: Daaweynta BCMA CAR-T ee Kacaanka ah oo si Buuxda u ah Aadanaha oo leh Waxtar iyo Badbaado Aan La Midayn

Heerarka Jawaabta Sare: FUCASO waxay ku faantaa Heerka Jawaab Celinta Guud (ORR) oo ah 98.9% iyo heerka Jawaab Celinta Dhammaystiran (CR) oo ah 82.4%, taasoo si weyn uga sarreysa daawaynta kale ee la heli karo.

Safiir WaaraBukaannada lagu daweeyay FUCASO waxay muujiyeen heer 12 bilood ah oo ah 85.5% oo ah Badbaadin La'aan Horumarineed (PFS), taasoo muujinaysa cafis muddo dheer ah iyo tayada nolosha oo soo hagaagtay.

Astaanta Badbaadada: Iyadoo cudurka Cytokine Release Syndrome (CRS) uu ku dhaco 1% oo keliya bukaanada oo aan la soo sheegin kiisas ah ≥3 heerka Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS), FUCASO waxay bixisaa ikhtiyaar daaweyn oo ammaan ah marka loo eego daaweynta kale ee CAR-T.

Waxtarka Kharashka: Daaweynta FUCASO waxay ku kacaysaa qiimo aad uga yar daawaynta la midka ah ee laga heli karo Mareykanka, taasoo ka dhigaysa ikhtiyaar macquul ah oo loogu talagalay bukaanno kala duwan.

Gaaritaanka Caalamiga ah: IASO BIO waxay ka aasaastay shabakad xarun daaweyn oo dhammaystiran dalka Shiinaha, oo awood u leh inay u adeegto bukaanada adduunka oo dhan iyadoo la adeegsanayo adeegyo isku dhafan laga bilaabo la-tashiga ilaa daryeelka daaweynta kadib.

Bukaankii ugu horreeyay ee lagu daweeyay FUCASO wuxuu gaaray shan sano oo badbaado ah oo aan kansar lahayn, taasoo ah tallaabo cajiib ah marka la barbar dhigo badbaadada Horumarka La'aanta ah (PFS) oo ah 2.9 bilood oo keliya iyadoo la adeegsanayo daryeel caadi ah. Tani waxay iftiiminaysaa awoodda FUCASO ay u leedahay inay beddesho muuqaalka daaweynta ee myeloma badan.