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Magulu a Chithandizo
Mankhwala Odziwika
Kufalitsa Large B-cell lymphoma (DLBCL)-04

Kufalitsa Large B-cell lymphoma (DLBCL)-04
Chithandizo cha CAR-T cha Myasthenia Gravis (MG)

Chithandizo cha CAR-T cha Myasthenia Gravis (MG)
Chithandizo cha Kachilombo ka Oncolytic: Chithandizo Chapamwamba cha Khansa

Chithandizo cha Kachilombo ka Oncolytic: Chithandizo Chapamwamba cha Khansa
Mnyamata akuvutika ndi khansa ya m'magazi ya acute lymphoblastic

Mnyamata akuvutika ndi khansa ya m'magazi ya acute lymphoblastic
Kugonjetsa Lymphoma Yaikulu ya B-Cell ndi Bioocus Dual CAR-T Therapy

Kugonjetsa Lymphoma Yaikulu ya B-Cell ndi Bioocus Dual CAR-T Therapy
Kulimbana ndi Khansa ya Hepatocellular ndi Bioocus GPC3 CAR-T Therapy

Kulimbana ndi Khansa ya Hepatocellular ndi Bioocus GPC3 CAR-T Therapy
Yankho Lodabwitsa mu Refractory Multiple Myeloma Pambuyo pa Chithandizo cha Maselo a CAR-T

Yankho Lodabwitsa mu Refractory Multiple Myeloma Pambuyo pa Chithandizo cha Maselo a CAR-T
Kupambana kwa Madhavan: Kugonjetsa Ubongo wa Glioma ndi Chithandizo cha Bioocus B7H3 CAR-T

Kupambana kwa Madhavan: Kugonjetsa Ubongo wa Glioma ndi Chithandizo cha Bioocus B7H3 CAR-T
Mnyamata wolimba mtima wochokera ku Russia akulimbana ndi neuroblastoma

Mnyamata wolimba mtima wochokera ku Russia akulimbana ndi neuroblastoma
Munthu wodzipereka wochokera ku India akulimbana ndi khansa ya m'mimba

Munthu wodzipereka wochokera ku India akulimbana ndi khansa ya m'mimba
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FUCASO: Chithandizo cha Revolutionary Fully-Human BCMA CAR-T chokhala ndi Mphamvu ndi Chitetezo Chosayerekezeka

FUCASO ndi njira yatsopano yochiritsira matenda a CAR-T yochokera ku BCMA yochokera ku IASO BIO, yomwe imapereka mphamvu komanso chitetezo chosayerekezeka pa matenda a myeloma yambiri yomwe yabwereranso kapena yokana. Ndi kuchuluka kwa mayankho, kuchira kokhazikika, komanso chitetezo champhamvu, FUCASO imapereka chiyembekezo chatsopano kwa odwala ndikukhazikitsa muyezo watsopano mu chithandizo cha CAR-T.

    Lumikizanani nafe
    Tsatanetsatane wa Zamalonda
    Ubwino Waukulu wa FUCASO
    Kupambana kwa Zachipatala

    tsatanetsatane wa malonda

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    FUCASO, yopangidwa ndi Nanjing IASO Biotechnology, ndi njira yatsopano yochiritsira matenda ya CAR-T yomwe cholinga chake ndi kuthana ndi maturation antigen a B-cell (BCMA). Njirayi imadziwika bwino chifukwa cha mphamvu zake zachipatala komanso chitetezo chake, zomwe zimapereka chiyembekezo chatsopano kwa odwala omwe ali ndi matenda obwereranso kapena osagwirizana ndi matenda a multiple myeloma (r/rMM). Yovomerezedwa ndi National Medical Products Administration (NMPA) pa June 30, 2023, FUCASO yawonetsa kale kupambana kwakukulu pakugwiritsa ntchito mankhwala.

    Ubwino Waukulu wa FUCASO

    Mitengo Yapamwamba YoyankhaFUCASO ili ndi Chiŵerengero Chonse Choyankha (ORR) cha 98.9% ndi Chiŵerengero Chonse Choyankha (CR) cha 82.4%, chokwera kwambiri kuposa mankhwala ena omwe alipo.

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    Chikhululukiro ChokhazikikaOdwala omwe adalandira chithandizo cha FUCASO awonetsa chiŵerengero cha 85.5% cha Progression-Free Survival (PFS) kwa miyezi 12, zomwe zikusonyeza kuti apuma kwa nthawi yayitali komanso moyo wawo umakhala wabwino.

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    Mbiri Yachitetezo: Popeza Cytokine Release Syndrome (CRS) ya kalasi ya ≥3 imapezeka mwa odwala 1% okha ndipo palibe milandu yodziwika ya ≥3 ya Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS), FUCASO imapereka njira yotetezeka yochizira poyerekeza ndi mankhwala ena a CAR-T.

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    Kugwiritsa Ntchito Ndalama MoyeneraChithandizo cha FUCASO chimawononga ndalama zochepa kwambiri poyerekeza ndi mankhwala ofanana omwe alipo ku United States, zomwe zimapangitsa kuti chikhale njira yabwino kwa odwala ambiri.

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    Kufikira Padziko Lonse: IASO BIO yakhazikitsa netiweki yonse ya malo ochiritsira odwala ku China, yomwe imatha kutumikira odwala ochokera padziko lonse lapansi ndi mautumiki ophatikizana kuyambira upangiri mpaka chisamaliro chothandizidwa pambuyo pa chithandizo.

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    Kupambana kwa Zachipatala

    Wodwala woyamba amene adalandira chithandizo cha FUCASO wakwanitsa zaka zisanu za moyo wopanda khansa, zomwe ndi zodabwitsa kwambiri poyerekeza ndi Progression-Free Survival (PFS) ya miyezi 2.9 yokha yokhala ndi chithandizo chanthawi zonse. Izi zikuwonetsa kuthekera kwa FUCASO kusintha malo ochiritsira matenda a multiple myeloma.

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