Matenda a Sickle Cell ndi Thalassemia

Ku BIOOCUS International Treatment Center, tikunyadira kudziwitsa anthu za Hemo-cell, chithandizo cha majini chatsopano chomwe chimapereka chiyembekezo chatsopano kwa odwala omwe akuvutika ndi matenda a sickle cell (SCD) ndi Thalassemia (TDT) yodalira kuikidwa magaziHemo-cell yapangidwa kuti ithetse vuto lalikulu la matendawa, ndipo imapereka chithandizo chomwe chingathe kuchiritsidwa kudzera mu chithandizo cha kamodzi kokha.

Kodi Hemo-cell ndi chiyani?

Hemo-cel ndi njira yotsogola yogwiritsira ntchito maselo a hematopoietic stem and progenitor cells (HSPCs) a wodwalayo, omwe amasinthidwa majini kuti apange hemoglobin yathanzi. Mwa kukonza jini yolakwika yomwe imayambitsa matenda a magazi, Hemo-cel ikhoza kusintha kwambiri miyoyo ya odwala, mwina kuthetsa kufunikira kwa magazi nthawi zonse ndikupereka yankho la moyo wonse.

Kodi Hemo-cell imagwira ntchito bwanji?

Njira yochizira imayamba potenga ma HSPC kuchokera m'magazi a wodwalayo. Kenako maselo amenewa amakulitsidwa kunja kwa thupi pogwiritsa ntchito lentiviral vector yomwe imayambitsa jini yosinthidwa ya β-globin. Maselo akakonzeka, amabwezeretsedwanso mwa wodwalayo, komwe amayamba kupanga maselo ofiira athanzi omwe amatha kupanga hemoglobin yogwira ntchito. Njirayi imabwezeretsa mgwirizano pakati pa unyolo wa α-globin ndi β-globin m'magazi, zomwe zimachepetsa bwino zizindikiro za kuchepa kwa magazi ndikulola wodwalayo kukwaniritsa. kudziyimira pawokha pakuika magazi.

Zotsatira Zotsimikizika

Mayeso azachipatala a Hemo-cell awonetsa kupambana kwakukulu:

• 100% ya odwala mu mayesowa adapeza bwino kulowetsedwa kwa mafupa.
• Odwala ambiri anakhala osadalira kuikidwa magazi mkati mwa milungu ingapo mutalandira chithandizocho.
• Wodwala m'modzi wakhala wopanda magazi kwa pafupifupi nthawi zaka zinayi popanda zotsatirapo zilizonse zoyipa.
• Mankhwalawa amathandizanso kuchepetsa kuchuluka kwa chitsulo m'thupi, vuto lomwe limafala kwambiri kwa odwala a TDT omwe amaikidwa magazi nthawi zonse.

Njira Yotetezeka

Mosiyana ndi njira zachikhalidwe monga kupatsa maselo oyambira a hematopoietic (HSCT), zomwe zimafuna wopereka wofanana ndipo zimakhala ndi zoopsa monga matenda a graft-versus-host (GVHD), Hemo-cell imagwiritsa ntchito maselo a wodwalayokupewa mavuto amenewa. Izi zimapangitsa kuti chithandizocho chikhale chothandiza. otetezeka ndipo odwala ambiri amatha kupeza mosavuta, popanda kufunikira chithandizo cha nthawi yayitali choletsa chitetezo cha mthupi.

Kukula Kwathu Padziko Lonse

Popeza tachita bwino kwambiri ku China, tsopano tikukulitsa kupezeka kwa Hemo-cel padziko lonse lapansi. Ndi mgwirizano wazachipatala mu Saudi Arabia, Thailand, Malaysia, ndi zina zambiri, tadzipereka kuti chithandizo chatsopanochi chipezeke kwa odwala padziko lonse lapansi.

Tsogolo Lopanda Kuikidwa Magazi

Hemo-cell imapereka tsogolo labwino kwa anthu omwe ali ndi matenda a SCD ndi beta-thalassemia. Tangoganizirani moyo wopanda magazi nthawi zonse, komanso kuthekera kochira kwamuyaya. Ku BIOOCUS, tadzipereka kuti masomphenyawa akhale enieni kudzera mu njira zamakono zochizira majini monga Hemo-cel.

Lumikizanani nafe lero kuti mudziwe zambiri za momwe Hemo-cell ingasinthire ulendo wanu wa chithandizo ndikukupatsani tsogolo labwino komanso labwino.