Cutar Sickle Cell da Thalassemia

A Cibiyar Kula da Jiyya ta BIOOCUS, muna alfahari da gabatar muku da Haemoglobin-cel, wani sabon maganin kwayoyin halitta wanda ke ba da sabon fata ga marasa lafiya da ke fama da cutar sikila (SCD) kuma thalassemia mai dogaro da jini (TDT)An tsara sinadarin Hemo-cel ne don magance matsalar da ke haifar da waɗannan yanayi, yana ba da damar warkewa ta hanyar magani sau ɗaya.

Menene Haemoglobin?

Hemo-cel magani ne mai ci gaba wanda ke amfani da ƙwayoyin halittar jini da na haihuwa (HSPCs) na majiyyaci, waɗanda aka gyara su ta hanyar halitta don samar da haemoglobin mai lafiya. Ta hanyar gyara kwayar halittar da ke da alhakin matsalar jini, Hemo-cel na iya inganta rayuwar marasa lafiya sosai, wanda hakan zai iya kawar da buƙatar ƙarin jini akai-akai da kuma samar da mafita ta tsawon rai.

Yaya Hemo-cel yake Aiki?

Tsarin magani yana farawa ne ta hanyar tattara HSPCs daga jinin majiyyaci. Daga nan sai a ƙara haɓaka waɗannan ƙwayoyin halitta a wajen jiki ta amfani da na'urar lentiviral wadda ke gabatar da kwayar halittar β-globin da aka gyara. Da zarar ƙwayoyin sun shirya, sai a sake haɗa su cikin majiyyaci, inda za su fara samar da ƙwayoyin jinin ja masu lafiya waɗanda za su iya samar da haemoglobin mai aiki. Wannan tsari yana dawo da daidaito tsakanin sarƙoƙin α-globin da β-globin a cikin jini, yana rage alamun rashin jini yadda ya kamata kuma yana ba majiyyaci damar cimma nasara. 'Yancin Kai ga Zubar da Ciki.

Sakamakon da aka Tabbatar

Gwaje-gwajen asibiti na Hemo-cel sun nuna Nasara mai ban mamaki:

• 100% na marasa lafiya a cikin gwajin an cimma nasarar sassaka ƙashi mai kyau.
• Yawancin marasa lafiya sun zama ba tare da an yi wa jini ba cikin makonni bayan maganin.
• An yi wa wani majiyyaci tiyata ba tare da an yi masa ƙarin jini ba tsawon kusan shekara guda. shekaru huɗu ba tare da wata babbar illa ba.
• Maganin yana kuma taimakawa wajen rage yawan sinadarin ƙarfe da ke taruwa a jiki, wani matsala da aka saba gani a cikin marasa lafiya da ke karɓar ƙarin jini akai-akai.

Madadin Mafi Aminci

Ba kamar jiyya ta gargajiya ba kamar dashen ƙwayoyin halitta na hematopoietic (HSCT), wanda ke buƙatar daidaitawar mai bayarwa kuma yana ɗauke da haɗari kamar cututtukan dasawa da kuma masu masaukin baki (GVHD). Hemo-cel yana amfani da ƙwayoyin halittar majiyyaci, guje wa waɗannan rikitarwa. Wannan yana sa maganin ya yi tasiri mafi aminci kuma ya fi sauƙi ga marasa lafiya da yawa, ba tare da buƙatar maganin rage ƙarfin garkuwar jiki na dogon lokaci ba.

Faɗaɗar Mu ta Duniya

Bayan mun sami gagarumar nasara a kasar Sin, yanzu muna fadada samuwar Hemo-cel a duk duniya. Tare da hadin gwiwar asibiti a cikin Saudi Arabia, Thailand, Malaysiada ƙari, mun himmatu wajen samar da wannan sabuwar hanyar magani ga marasa lafiya a duk faɗin duniya.

Makomar da Ba Za a Iya Yi Ba Ba Tare da Karin jini ba

Hemo-cel yana ba da kyakkyawar makoma ga waɗanda suka kamu da cutar SCD da beta-thalassemia. Ka yi tunanin rayuwa ba tare da ƙarin jini akai-akai ba, tare da yuwuwar samun waraka ta dindindin. A BIOOCUS, mun himmatu wajen tabbatar da wannan hangen nesa ta hanyar hanyoyin magance kwayoyin halitta na zamani kamar Hemo-cel.

Tuntube mu yau don ƙarin koyo game da yadda Hemo-cel zai iya canza tafiyarku ta magani da kuma samar da makoma mai haske da koshin lafiya.