Izindaba
Ukwelashwa kwe-BioOCUS Medical Group's Dual CD19/BCMA CAR-T Kuletha Imiphumela Ethembisayo ku-Refractory Myasthenia Gravis: Uhambo Lwesiguli Esisesincane
Isiguli sase-Australia Sithola Impendulo Emangalisayo Yasekuqaleni Ngokwelashwa Okubili Kwe-CD19/CD20 CAR-T Kwe-BIOOCUS Medical Group Kwe-DLBCL Ebuye Yaphela
Ukubaluleka Kokulandelela Okuvamile Nokuhlolwa Ngemva Kokufakelwa Kwamaseli E-Hematopoietic Stem
Ukulandelela ngemva kokufakelwa kubalulekile ezigulini ezifakelwe amaseli e-hematopoietic stem cell (HSCT). Ukuhlolwa njalo kusiza ekutholeni izinkinga ezifana nokutheleleka, isifo se-graft-versus-host (GVHD), kanye nokubuyela emuva, okuqinisekisa ukungenelela kusenesikhathi kanye nemiphumela engcono.
Ukwelashwa kwe-CAR-T Kunqoba Ukubikezela Okubi ku-Lymphoma Ye-B-Cell Esezingeni Eliphezulu
Ucwaningo olusha lubonisa ukuthi ukwelashwa kwe-CAR-T kungathuthukisa ukubikezela kweziguli ezine-B-cell lymphoma (HGBL) yebanga eliphezulu, uhlobo lwe-B-cell lymphoma enkulu, ngisho nasemigqeni yokwelashwa kamuva, okunikeza ithemba elisha ngala macala ayinselele.
Ukungenelela Kwasekuqaleni Ngokwelashwa Kwe-CAR-T Kwe-B-Cell Lymphoma Enkulu Kubonisa Imiphumela Ethembisayo
Ucwaningo olubheka emuva oluqhathanisa ukwelashwa kwe-CAR-T kwasekuqaleni nokwephuzile ezigulini ezinkulu ze-B-cell lymphoma lwembula ukuthi ukwelashwa kwasekuqaleni kunganikeza amazinga okusinda athuthukisiwe kanye nemiphumela emibi embalwa, okusekela ukusetshenziswa kwayo njengokwelashwa komugqa wesibili.
Ukwelashwa kwe-CAR-T Kubonisa Ukuphepha Nokusebenza Kahle Ezigulini Zomdlavuza Ezinezifo Ezizimele Noma Ezivuvukalayo
Ucwaningo lwamuva nje olushicilelwe ku- I-Lancet Rheumatology kukhombisa ukuthi ukwelashwa ngamaseli e-CAR-T kuphephile futhi kuyasebenza ekwelapheni i-lymphoma kanye neziguli eziningi ze-myeloma ezinezifo zokuzivikela komzimba noma zokuvuvukala, okunikeza ubufakazi obuthembisayo bokusetshenziswa kwayo kabanzi.
Ukuqonda Okusha Ngezinhlobo Ezincane Zezakhi Zofuzo Zabantu Abadala B-ALL
Isibuyekezo esiphelele ku Igazi iqokomisa intuthuko yakamuva ekuqondeni izinhlobo zezakhi zofuzo ze-B-cell Acute Lymphoblastic Leukemia (B-ALL) yabantu abadala. Ucwaningo luhlola ukungafani kwezinto eziphilayo, imiphumela yezokwelapha, kanye nokubaluleka komuthi onembile ekuthuthukiseni imiphumela yeziguli.
Ucwaningo Oluphumelelayo Luqinisekisa Ukuphepha Nokusebenza Kahle Kokwelashwa Kwe-CD19/CD20 CAR-T Kwe-r/r B-NHL
Isivivinyo sesigaba sokuqala sezikhungo eziningi eShayina sibonise ukuphepha nokusebenza kahle okuthembisayo kwe-prizlon-cel, ukwelashwa kwe-CD19/CD20 CAR-T okuqondiswe kabili, okunikeza ithemba elivuselelwe ezigulini ezine-lymphoma ye-B-cell non-Hodgkin ephinde yabuya/engasasebenzi (r/r B-NHL).
Ama-Biomarker Amasha Abikezela Imiphumela Yokwelashwa Kwe-CAR-T Ekwelashweni Kwe-Multiple Myeloma
Ucwaningo lwamuva nje olushicilelwe ku- Igazi ikhomba amazinga e-BCMA (sBCMA) ancibilikayo kanye nevolumu yesimila esishintshashintshayo (i-MTV) njengezimpawu ezibikezela imiphumela yokwelashwa kwe-CAR-T ezigulini ezine-myeloma eminingi (RRMM) ephinde yaphindeka futhi engaphili kahle, okuvula indlela yamasu okwelashwa aqondene nawe.
Ukwelashwa kwe-CAR-T: Ikusasa Elithembisayo Lezigameko Zokugula Ezibangelwa Amaseli E-T
Ukwelashwa kwe-CAR-T, ekuqaleni okwakuyintuthuko enkulu ekwelapheni umdlavuza we-B-cell, kubonisa ithemba ekwelapheni ama-T-cell lymphomas kanye ne-T-cell acute lymphoblastic leukemia (T-ALL). Lokhu kwelashwa okuguqukayo kubhekene nezinselele ezihlukile kodwa izivivinyo zakamuva zemitholampilo zinikeza ithemba lezixazululo ezintsha zokwelapha umdlavuza we-T-cell.
Ucwaningo Olusha Olushicilelwe Ku-Blood: Ukwelashwa Kwe-CD7 CAR-T Okusekelwe Ku-Nanobody kwe-Acute Myeloid Leukemia
Ithimba Lezokwelapha laseLu Daopei lifinyelele intuthuko enkulu ekwelapheni i-Acute Myeloid Leukemia (AML) ngocwaningo lwabo ngokwelashwa kwe-CD7 CAR-T okusekelwe ku-nanobody, okushicilelwe ephephabhukwini elidumile. Igazi.
Ama-Menin Inhibitors: Ukwelapha Okumangalisayo Kwe-Acute Myeloid Leukemia
Intuthuko yakamuva kuma-Menin inhibitors inikeza izinketho zokwelapha ezithembisayo ze-acute myeloid leukemia (AML), ihlose ukuguquka kwezakhi zofuzo futhi inikeze ithemba elisha lamacala anzima.