He keikikāne kūpaʻa mai Rusia e hakakā ana me ka neuroblastoma

Aia kekahi koa liʻiliʻi paʻakikī i kapa ʻia ʻo Kuvatov Emin. He 8 ona makahiki, a no Rusia mai ʻo ia. No ke aha mākou e mahalo ai i kona kūpaʻa? Eia kāna moʻolelo ikaika.

Ua ʻike ʻia ʻo Emin me ka neuroblastoma ma mua o ʻelima mau makahiki i hala aku nei, ua hoʻonohonoho ʻia ma ke ʻano he IV me ka metastasis iwi iwi a me ka loaʻa ʻana o MYCN. Ua hana ʻo ia i ka chemotherapy hoʻokomo ikaika, ke ʻoki kino, ka hoʻoili ʻana o nā cell stem autologous, a me ka hoʻōla ʻana i ka hoʻokaʻawale ʻana, e hoʻokō ana i ka hoʻomaha mua. Eia nō naʻe, ua loaʻa nā relapses, e pili ana i nā iwi a me nā lymph nodes, ʻoiai nā regimens laina lua e like me bevacizumab, irinotecan, temozolomide, a me ka hoʻoili allogeneic. I ka makahiki 2025, ua hōʻike nā scans MIBG i ka holomua me nā lesions hou, e koi ana i kona ʻohana e ʻimi i nā koho honua.

Ma BIOOCUS, ua loiloi manuahi ʻia ka hihia o Emin e kā mākou poʻe loea, nāna i ʻike iā GD2 CAR-T ma ke ʻano he lāʻau hoʻōla hoʻohiki. Ma hope o ka hoʻomaʻamaʻa mua ʻana me fludarabine a me cyclophosphamide, ua hoʻokomo ʻia nā pūnaewele CAR-T me ka ʻole o nā pilikia. Ua ikaika ka hoʻonui ʻana, me ka piʻi nui ʻana o nā waiwai paʻa i ka lā 7. Ua pale aku ka nānā makaʻala o kā mākou hui i nā hanana ʻino, a ua hōʻoia ka pathology i ka hopena o ka lāʻau lapaʻau ma kāna puʻupuʻu i hoʻokaʻawale maikaʻi ʻole ʻia.

Aia nā pono o BIOOCUS i kā mākou ʻano hana kiʻekiʻe, i kau ʻia ma ke kikowaena o ka mea maʻi a me nā huahana CAR-T hou. Hāʻawi mākou i ka lāʻau lapaʻau pololei i loko o kahi ʻano kākoʻo, me nā lawelawe e komo pū ana me ka hoʻonohonoho honua maʻalahi, ke aʻo ʻana i ka ʻohana, a me ka nānā ʻana ma hope o ka mālama ʻana. Mahalo nā mākua o Emin i ka mālama aloha i hoʻomāmā i ko lākou hopohopo i kēia manawa koʻikoʻi.