Imibuzo Evame Ukubuzwa-TIL Therapy kwa-BIOOCUS

U.
Kuyini Ukwelashwa kwe-TIL?

A.

Ukwelashwa nge-TIL (Tumor-Infiltrating Lymphocyte) kuyindlela yokwelapha nge-immunotherapy lapho ama-T-cell avela esimila sesiguli eqoqwa khona, anwetshwe elabhorethri, bese ephinde afakwe esigulini ukuze ahlasele amaseli omdlavuza.
U.
Inqubo yokwelapha i-TIL ithatha isikhathi esingakanani?

A.
Inqubo yokwelapha i-TIL ivame ukuthatha cishe amasonto ayi-6-8. Isinyathelo sokuqala sokuqoqwa kwezicubu zesimila kanye nokutshalwa kwamaseli e-T elabhorethri sithatha amasonto ama-3-4, kulandele ukulungiswa kwe-chemotherapy kanye nokufakwa kwe-TIL.
U.
Yiziphi izinhlobo zomdlavuza ezingelashwa ngokwelashwa kwe-TIL?

A.
Ukwelashwa kwe-TIL kusetshenziselwa ikakhulukazi izimila eziqinile njenge-melanoma, umdlavuza wamaphaphu, umdlavuza wesibeletho, kanye neminye imidlavuza ethuthukile noma esakazekile. Ukufaneleka kusekelwe ohlotsheni lwesimila kanye nempendulo yokwelashwa kwangaphambilini.
U.
Yimiphi imiphumela emibi okufanele ngiyilindele ekwelashweni kwe-TIL?

A.
Imiphumela emibi yokwelashwa kwe-TIL ingafaka ukukhathala, umkhuhlane, isicanucanu, kanye ne-cytokine release syndrome (CRS). Njengase-CAR-T, ukwelashwa kuqashwe ngokucophelela ukuqinisekisa ukuphepha kwesiguli.
U.
Ngilungiselela kanjani ukwelashwa kwe-TIL?

A.
Njengoba kunjalo nge-CAR-T, ukulungiselela kuhilela ukuhlolwa okuphelele kwezokwelapha, okuhlanganisa ukuthwebula izithombe, ukuhlolwa kwegazi, kanye ne-biopsy yesimila. Uma sesifanelekile, sizoxoxa ngemininingwane yenqubo futhi sihlele ukuhamba kwesikhathi sokuhlala kwakho eShayina.
U.
Ngingahamba nomuntu engizomphelezela ngesikhathi sokwelashwa?

A.

Yebo, sikhuthaza iziguli ukuthi zilethe ilungu lomndeni noma umngane ukuze azosekela ngesikhathi sokuhlala kwazo. Sinikeza usizo ngendawo yokuhlala kanye namalungiselelo okuhamba komngane wakho.
U.
Ngingahlela kanjani uhambo oluya e-BIOOCUS ukuze ngiyokwelashwa?

A.

I-BIOOCUS inikeza ukwesekwa okuphelele kweziguli zakwamanye amazwe, okuhlanganisa usizo lwe-visa, izincomo zendiza, kanye namalungiselelo okuhlala. Sizokuqondisa kule nqubo futhi siqinisekise ukuthi ukufika kuhamba kahle.
U.
Kubiza malini ukwelashwa kwe-TIL kwa-BIOOCUS?

A.
Izindleko zokwelapha nge-TIL kwa-BIOOCUS zivame ukusuka ku-$100,000 kuya ku-$150,000 USD, kuye ngokuthi ukwelashwa kuyinkimbinkimbi kangakanani kanye nokunakekelwa okulandelayo okudingekayo.
U.
Kwenzekani uma ngidinga ukwelashwa okwengeziwe kwe-TIL ngemva kokumfaka okokuqala?

A.
Uma ukwelashwa kwe-TIL kufakazela ukuthi kuyazuzisa, kodwa umdlavuza ubuya, kungase kucatshangelwe ukufaka okunye. Sizoqapha intuthuko yakho futhi sixoxe nganoma yiziphi ezinye izindlela zokwelapha ngemva kokufaka kokuqala.
U.
Yikuphi ukunakekelwa kokulandelela okudingekayo ngemva kokwelashwa kwe-TIL?

A.
Ngemva kokwelashwa kwe-TIL, iziguli zizodinga ukuhlolwa njalo ukuze zilandelele impendulo yomdlavuza futhi ziphathe noma yimiphi imiphumela yesikhathi eside. Lokhu kungafaka phakathi izithombe, ukuhlolwa kwegazi, kanye nokuqapha amasosha omzimba.
U.
Ingabe ikhona ingozi yokuthi umdlavuza uphinde ubuye ngemva kokwelashwa nge-TIL?

A.
Nakuba ukwelashwa kwe-TIL kunganikeza ukuphulukiswa okuhlala isikhathi eside, kuhlale kunengozi yokuphinda umdlavuza. Ukuqapha okuqhubekayo nokunakekelwa kokulandelela kubalulekile ukuze kutholakale noma yiziphi izimpawu zokubuyela emuva kusenesikhathi.