Ukwelapha Okusha Kwe-CAR-T Ku-B-cell Acute Lymphoblastic Leukemia Kubonisa Ukusebenza Okungakaze Kubonwe Ngaphambili
Ucwaningo lwamuva nje lulethe izindaba ezithembisayo ezigulini ezihlushwa yi-B-cell Acute Lymphoblastic Leukemia (B-ALL), lubonisa ukusebenza kahle okumangalisayo nokuphepha kokwelashwa kwe-chimeric antigen receptor-T cell (CAR-T). Lolu cwaningo, olwenziwe ngokubambisana ne-BIOOCUS kanye neLu Daopei Hospital, lugcizelela amandla okwelashwa kwe-CAR-T okuguqula ukwelashwa kwalolu hlobo olunamandla lwe-leukemia.
Ucwaningo luhlole ngokucophelela imiphumela yezokwelapha yeziguli ezelashwe ngamaseli e-CAR-T, lugxile ekhonweni lazo lokuqondisa nokuqeda amaseli e-B anomdlavuza. Imiphumela yayimangalisa kakhulu, kanti ingxenye enkulu yeziguli ithole ukuphulukiswa okuphelele. Le mpumelelo ayigcini nje ngokugqamisa amandla okwelashwa kwe-CAR-T kodwa futhi iyibeka njengenketho yokwelapha ehamba phambili ye-B-ALL.
I-BIOOCUS, ngokubambisana neSibhedlela esidumile saseLu Daopei, ibilokhu ihamba phambili kulolu cwaningo olusha. Ukubambisana phakathi kwalezi zinhlangano ezimbili kube negalelo elikhulu ekuthuthukiseni ukwelashwa kwe-CAR-T, ukuqinisekisa ukuthi iziguli zithola ukwelashwa okusezingeni eliphezulu okusekelwa ucwaningo lwesayensi oluqinile. Lolu cwaningo lugcizelela ukubaluleka kokubambisana okunesu ekuthuthukisweni kwezindlela zokwelapha ezisindisa impilo.
Umphakathi wezokwelapha wamazwe ngamazwe uqaphele lokhu okutholakele, uqaphela umthelela oguqulayo wokwelashwa kwe-CAR-T ku-oncology. Njengoba iziguli ze-B-ALL emhlabeni wonke zifuna izindlela zokwelapha ezisebenzayo, lolu cwaningo lunikeza ithemba elisha, luqinisa indima yokwelashwa kwe-CAR-T esikhathini esizayo Ukwelashwa Komdlavuza.
Kuziguli nemindeni elwa ne-B-ALL, ucwaningo lunikeza ithemba. Ngokuqhubeka kwentuthuko kanye nokusekelwa kwezinhlangano ezifana ne-BIOOCUS kanye ne-Lu Daopei Hospital, ikusasa lokwelashwa kwe-CAR-T libukeka liqhakazile kunanini ngaphambili.
Uma wena noma othandekayo wakho nithintekile yi-B-cell Acute Lymphoblastic Leukemia futhi ninesifiso sokuhlola ukwelashwa kwe-CAR-T, sikumema ukuthi usithinte ukuze uthole ulwazi olwengeziwe. Ithimba lethu elizinikele lilapha ukukusekela kuzo zonke izinyathelo zohambo lwakho lokwelashwa.