Ulutsha Lufumana Ithemba Emva Kokuxilongwa Nge-AML M4a Uhambo Lokuqina Nokuchacha

Ngowama-2014, inkwenkwana egama linguXiao Pi (alias) yafunyaniswa ukuba ine-acute myeloid leukemia (AML). Nangona yayisele iphilile emva kokuthatha i-chemotherapy izihlandlo ezibini, iingxaki ezibangelwa zizifo ezinzima zamshiya ediniwe ngokwasemzimbeni nangokweemvakalelo, nto leyo eyamenza ukuba ayeke unyango lwakhe aze afune unyango olungezinye.

Ngowama-2016, imeko kaXiao Pi yaphinda yabuya, uvavanyo oluqinisekisa i-AML-M4a lwaza lwatyhila utshintsho oluntsonkothileyo lwezakhi zofuzo, kuquka i-DEK-CAN kunye ne-NRAS. Emva kwezihlandlo ezininzi zokusebenzisa i-chemotherapy engasebenziyo, uXiao Pi wajongana nokuphelelwa lithemba, ezibuza ukuba angaphila na.

NgoSeptemba 2018, uXiao Pi wafuna uncedo kwiSibhedlele iLu Daopei, efumana ithemba kuGqr. Xiong Min kunye neqela lakhe lokufakelwa isibeleko. Uvavanyo olupheleleyo lwatyhila i-prognosis enzima, kuquka ipesenti ephezulu yeeseli ezinobungozi kunye nokuphazamiseka okuntsonkothileyo kwe-chromosome. Nangona kunjalo, iqela likaGqr. Xiong lenze irejimeni ye-chemotherapy eyenzelwe wena.

Iziphumo zizise utshintsho olukhulu: emva kwemijikelo emibini ye-chemotherapy, iiseli ezinobungozi zikaXiao Pi zehla kakhulu, kwaye amanqanaba akhe amancinci esifo esisele (MRD) aphucuka kakhulu. Efumana ukuzithemba kwakhona, uXiao Pi walungiselela inyathelo elilandelayo: ukufakelwa kweeseli ze-hematopoietic stem cell (HSCT) esebenzisa umntakwabo njengomxhasi.

NgoNovemba ka-2018, uXiao Pi waphumelela ukufakelwa isitho. Nangona kukho iingxaki ezincinci ngexesha lokufakelwa isitho sangaphambili kunye nesifo se-graft-versus-host emva kokufakelwa isitho sangaphambili (i-GVHD), inkqubo yaba yimpumelelo. Ukuchacha kukaXiao Pi kwajongwa ngokusondeleyo kwaye kwalawulwa, okwamvumela ukuba oyise le miqobo.

Ngoku, emva kweminyaka emihlanu emva kokufakelwa isidoda, uXiao Pi uyachuma. Njengomfana osempilweni nozithembileyo, uqhubeka nezifundo zakhe kwiyunivesithi ayikhethileyo, ebonisa ukuqina nokuzimisela okwachaza uhambo lwakhe.

Isigidimi Sombulelo
Usapho lukaXiao Pi luvakalise umbulelo osuka entliziyweni kuGqr. Xiong Min, uGqr. Wang Gen, uGqr. Cui Zhen, kunye neqela lonke lezonyango, abanobuchule babo kunye novelwano lwabo lwaguqula ukuphelelwa lithemba laba lithemba.

"Ngaphandle kwemizamo engadinwayo yeqela leSibhedlele saseLu Daopei, ukuzalwa kwakhona kukaXiao Pi bekungenakwenzeka. Sihlala sibulela."