Ukusuka Ekungakwazini Kwe-Graft Ekuqaleni Ukuya Ekubuyeleni Ngokupheleleyo: Uhambo Lwesigulana NgeProtokholi Yokufakelwa Kwesigulana Ephambili KaLu Daopei
Ekuqaleni kowama-2024, umfazi kaMnu. A (igama lakhe alichazwanga) wafunyaniswa ukuba une-B-lymphoblastic leukemia enobungozi obuphezulu, nto leyo eyabangela ukuba ubomi bakhe bube sempilweni kwaye bube namandla. Ekuqaleni, wafumana i-chemotherapy enamandla waza wangeniswa kwi-bone marrow transplant kunye noyise njengomnikeli. Nangona kunjalo, amathemba akhe aphela ngokukhawuleza xa ukufakelwa kwe-transplant kungaphumeleli—ingxaki engaqhelekanga kodwa esongela ubomi eyaziwa ngokuba yi-"primary graft failure."
Kule meko ibalulekileyo, apho iindlela zonyango zazinqongophele, uMnu. A wanikwa ukhetho olunzima: ukuzama ukufakelwa okwesibini. Nangona wayenomngeni, iqela lezonyango laseLu Daopei labelane ngeziphumo ezikhuthazayo ezivela kwiprothokholi entsha yokufakelwa kwakhona ababeyiphuhlisile, beqhayisa ngesantya esimangalisayo sempumelelo. Bezaliswe lithemba elitsha, usapho lwajongana nomnye umqobo: ukufumana umxhasi ohambelanayo. Emva kokuba izalamane ezili-14 zivavanyiwe kungekho mntu uhambelanayo, iqela lezonyango laqalisa ukukhangela umxhasi ongengowazalamane. UFortune wabancumela, kwaye kwiveki nje enye, kwafunyanwa umxhasi ohambelanayo ngokupheleleyo, ongenalwalamano naye waza wavuma ukuba nikela.
Ngomhla wesi-3 kuSeptemba ngo-2024, ukufakelwa okwesibini kwaqala. Emva kweentsuku ezisithoba emva kokufakelwa, inani leeseli zakhe ezimhlophe zegazi laqala ukunyuka, kwaye ngomhla we-19, wayesele ezinzile ngokwaneleyo ukuba ashiye ukwahlukana, kwaye amanqanaba akhe egazi abuyela esiqhelweni emva koko. Ukususela ngoko ukhululwe kwaye iziphumo zakhe zihlala zihambelana novavanyo lwe-bone marrow kunye ne-chimerism.
Ecinga ngohambo lwabo, uMnu. A uvakalise umbulelo onzulu ngenkxaso nobuchule beqela laseLu Daopei, ububele bomnikeli we-marrow, kunye nabasebenzi bezonyango abanike ithemba ngamaxesha obumnyama. La mava aqinise uxabiso lwabo ngobomi kwaye agxininisa amandla okunyamezela, ubuchule, kunye novelwano xa bejamelene neengxaki ezibonakala zingenakunqotshwa.