Kubva Pakukundikana Kwekutanga Kuisa Chigadzirwa Chemushonga Kusvika Pakupora Kwakazara: Rwendo rweMurwere neChirongwa cheLu Daopei cheAdvanced Transplant Protocol
Pakutanga kwa2024, mudzimai waVaA (zita risingazivikanwe) akaonekwa aine chirwere cheB-lymphoblastic leukemia chine njodzi huru, zvichiratidza mumvuri wehupenyu hwaimbova hwakanaka uye hwakasimba. Pakutanga, akapihwa chemotherapy yakasimba uye akabvumidzwa kuisirwa mubofu marrow nababa vake semupi wechirwere. Zvisinei, tariro yake yakazopera apo kuisirwa mubofu kwakatadza kupinza mubofu—dambudziko risingawanzoitiki asi rinotyisidzira hupenyu rinozivikanwa se "primary graft failure."
Panguva iyi yakaoma, nesarudzo shoma dzekurapa, VaA vakapihwa sarudzo yakaoma: kuedza kuisirwa kechipiri. Kunyange zvazvo zvainetsa, timu yekurapa yeLu Daopei yakagovana mhedzisiro inokurudzira kubva muchirongwa chitsva chekuisirwazve chirwere chavakanga vagadzira, ichiratidza kubudirira kukuru. Vazere netariro itsva, mhuri yakatarisana nechimwe chipingamupinyi: kuwana mupi anoenderana. Mushure mekunge hama gumi neina dzaongororwa pasina mubatsiri, timu yekurapa yakatanga kutsvaga mupi anoenderana nevamwe vasiri hama. Fortune akavanyemwerera, uye mukati mevhiki imwe chete, mupi anoenderana zvakakwana, asina hukama akawanikwa uye akabvuma kupa.
Musi wa3 Gunyana, 2024, kuisirwa kwechipiri kwakatanga. Mazuva mapfumbamwe mushure mekuisirwa, huwandu hwemasero machena eropa rake hwakatanga kukwira, uye pakasvika zuva rechi19, akanga agadzikana zvakakwana kuti abve ari ega, huwandu hweropa rake huchidzokera pakare. Kubva ipapo akaburitswa mushure mekuongororwa kwemapfupa nekuongorora chimerism.
Vachifunga nezverwendo rwavo, VaA vakatenda zvikuru rutsigiro nehunyanzvi hwechikwata cheLu Daopei, rupo rwevaya vanopa rubatsiro, pamwe nevashandi vekurapa vakapa tariro munguva dzakaoma. Chiitiko ichi chakasimbisa kukoshesa kwavo hupenyu uye chakasimbisa simba rekutsungirira, hunyanzvi, uye tsitsi mukutarisana nematambudziko anoita seasingakundiki.