Melanoma ya metastatic-04

Umurwayi Bwana Li, umugabo w'imyaka 45, yatangiye kugira ububabare bw'inda budashira no kugabanya ibiro mu ntangiriro za Werurwe 2022. Ibizamini byakurikiyeho mu bitaro byo muri ako gace byatumye asuzumwa muri Mata 2022 arwaye melanoma ya metastatic. Nubwo yagerageje uburyo butandukanye bwo kuvura, harimo kubagwa, kuvurwa hakoreshejwe imirasire, na chimiotherapie, indwara ye yakomeje kwangirika, aho ibibyimba byakwirakwiriye mu mwijima no mu bihaha.

Nyuma yo kugerageza uburyo busanzwe bwo kuvura bitagenze neza, Bwana Li yashatse ubundi buryo bwo kuvura mu Kuboza 2022 abifashijwemo n'abaganga. Nyuma yo kugisha inama cyane no gukora ubushakashatsi, yahisemo kugerageza uburyo bushya bwo kuvura indwara ziterwa n'ibibyimba bwitwa Tumor-Infiltrating Lymphocyte (TILs).

Uburyo bwo kuvura bwa TILs:

1. Gukuramo icyitegererezo cy'ikibyimba: Muri Mutarama 2023, Bwana Li yabazwe gato kugira ngo akuremo igice cy'ingingo y'ikibyimba.

2. Kwaguka kwa Lymphocyte: Muri laboratwari, abashakashatsi bakuyemo Lymphocyte zinjira mu tumori (TILs) mu gipimo cyakuwemo. Izi lymphocyte zongerewe inshuro nyinshi muri vitro kugira ngo zigere ku gipimo gikenewe cyo kuvurwa.

3. Gutegura imiti igabanya ubukana bw'imiti: Mbere yo guterwa uturemangingo twa TIL, Bwana Li yafashwe imiti igabanya ubukana bw'imiti isanzwe mu mubiri we, bituma haboneka umwanya w'uturemangingo twa TIL twashyizwemo.

4. Gutera TILs Selingi: Muri Werurwe 2023, selingi za TIL zagutse zongeye gushyirwa mu mubiri wa Bwana Li binyuze mu gutera imitsi.

5. Ubuvuzi bufasha: Kugira ngo hongerwe imikorere ya TILs, Bwana Li yanatewe inshinge nyinshi za Interleukin-2 (IL-2).

Mu mezi yakurikiye ubuvuzi, indwara ya Bwana Li yarushijeho kuba nziza cyane. Ibibyimba byagabanutse cyane, kandi ibisebe bya metastasis byagaragaje ko byagabanutseho igice. Ibyakurikiyeho muri Kamena 2023 byagaragaje ko ibibyimba mu mwijima no mu bihaha byari hafi gucika burundu. Ubuzima bwa Bwana Li muri rusange bwagiye busubirana, ibiro bye byongera kugaruka, kandi ububabare bwo mu nda bugabanuka.

"Ubwo namenyaga uko merewe, numvise nk'aho isi yose irimo gusenyuka. Nyuma yo kuvurwa inshuro nyinshi nta cyo maze, nari hafi gutakaza icyizere. Ku bw'amahirwe, nahuye n'ubuvuzi bwa TILs, butarokoye ubuzima bwanjye gusa ahubwo bwanansubije icyizere cy'ejo hazaza. Ndashimira abaganga n'abashakashatsi bose bamfashije. Ni imbaraga zanyu zampaye ubuzima bushya. Nizeye ko ubu buryo bushobora gufasha abarwayi benshi nkanjye gutsinda kanseri no kongera kugira ubuzima bwiza."