Dr. Lu Peihua Vanoratidza Kubudirira Mukurapa kweCAR-T paMusangano weGore we29 weAPBMT
Kubva musi wa10 kusvika 13 Gumiguru, 2024, Musangano weGore negore wechi29 weAsia-Pacific Blood and Marrow Transplantation (APBMT) wakaitwa kuSingapore General Hospital, pasi pedingindira rinoti “Kushandisa Sisitimu yeMuviri.” Senyanzvi inotungamira kubva kuChina, Dr. Lu Peihua vakakokwa kuti vape hurukuro huru, vachiratidza kubudirira kunoshamisa kwechikwata chavo mukushandura kwekiriniki nekushandisa CAR-T cell therapy, kunyanya mukurapa kenza yeropa.
Yakavambwa muna 1990, APBMT ndeimwe yemisangano yakakosha yekuongorora ropa nekuisirwa kwemapfupa mudunhu reAsia-Pacific. Iine nhengo dzinobva kunyika makumi maviri nembiri, inoshanda sepuratifomu yekubatsirana yekugovana tsvakurudzo yepamusoro uye budiriro yekiriniki mukuisa masero eropa uye kurapwa kwemasero.
Muhurukuro yavo ine musoro unoti "Real-world Data of Academic CAR-T Therapies in China," Dr. Lu vakaratidza kubudirira kwekurapa kwakaitwa neCD7 CAR-T therapy kune varwere vane kenza yeropa yakadzoka kana kuti isingashande. Varwere vazhinji, avo vakanga vasara nesarudzo shoma, vakawana zororo rakazara nekurapwa kweCAR-T, uye kune vamwe, mamwe marapirwo akabatanidzwa akadai sekuisirwa bone marrow akapa zororo renguva refu uye mukana wekurapwa.
Mharidzo yaDr. Lu yakakwezva vanhu vakawanda, nyanzvi dzakawanda dzichiratidza kufarira kushanda pamwe chete. Mushure mehurukuro, vanachiremba vekuSingapore General Hospital vakachinjana ruzivo rwekuonana naDr. Lu, vachiongorora hukama hwemangwana. Vakafadzwa zvikuru nemhedzisiro yekurapwa yakawanikwa nechikwata chake uye vakaratidza kufarira kutumira varwere kuChina kuti vanorapwa neCAR-T.
Seimwe yemasangano anotungamira munharaunda yeAsia-Pacific, Singapore General Hospital inopa hwaro hwakasimba hwekushandira pamwe mune ramangwana mune zvese tsvakiridzo uye mukurapa. Dr. Lu vakasimbisa kukosha kwekudyidzana kwakadaro mukusimudzira hematology uye kuisirwa kwemapfupa emapfupa kuti varwere vabatsirwe pasi rese.
Dr. Lu Peihua, neruzivo rwake rwakakura mukurapa kweCAR-T, anga achigara achipa hurukuro pamisangano yepasi rose yakaita seAPBMT. Mharidzo yake yazvino yakaratidza zvakare mukana wekurapa kweCAR-T kuvandudza mhedzisiro yevarwere, kukurudzira tsvakiridzo yakawedzerwa, uye kukurudzira kushanda pamwe chete pasi rose. Chikwata chake chinoramba chakazvipira kupa mishonga mitsva uye yakagadzirirwa munhu, ichiva nechokwadi chekuti varwere vanobatsirwa nekufambira mberi kwazvino mune zvesainzi yekurapa.
Kuburikidza nekushandira pamwe kwepasi rose uye kugovana ruzivo, chikwata chaDr. Lu chine chinangwa chekuvandudza nzira dzekurapa varwere vane kenza yeropa nezvimwe zvirwere zveropa, vachivavarira ramangwana apo mishonga mitsva inogona kupa mhinduro dzinogara kwenguva refu.