Malunga nenkampani yethuIsishwankathelo soNyango lwe-CAR-T

I-CAR-T Therapy, isifinyezo segama elithi Chimeric Antigen Receptor T-Cell Immunotherapy, yindlela yonyango oluphucukileyo lwezakhi zofuzo equka ukuguqula izakhi zofuzo zeeseli ze-T zesigulana ukuze zijolise kwaye zitshabalalise iiseli zomhlaza. Ngokungafaniyo namayeza emveli, unyango lwe-CAR-T lulungiselelwe isigulana ngasinye kwaye lufuna ukuqokelela iiseli ze-T egazini lesigulana ngaphambi kokuba ziphinde zifakwe emzimbeni emva kobunjineli bezakhi zofuzo.

ISISHWANKATHELO SONYANGO LWE-CAR-T (1)smn

Hlola Iimpawu

Iimpawu ze-CAR-T

● I-B-cell acute lymphoblastic leukemia

● I-myeloma eninzi

● I-leukemia engapheliyo ye-lymphocytic

● I-lymphoma engeyiyo iHodgkin

● Ukusasaza i-lymphoma enkulu ye-B-cell

● I-SLE (i-Systemic Lupus Erythematosus)

Ukusebenza kakuhle kweklinikhi ye-CAR-T

Iimpawu zeCD19+20CAR-T: Izigulane ezine-B-cell non-Hodgkin's lymphoma

Izinga le-CR lenyanga enye	Izinga le-PR lenyanga enye	Inyanga enye okanye izinga le-OR	I-CRS≥3	I-CRES≥3
71.95% (59/82)	25.6 (21/82)	97.55（80/82）	12.19% (10/82)	0

Iimpawu ze-CD19+22CAR-T: Unyango lwe-CD19 ephinde yabuyela kwi-CD19 kwaye izigulane ezine-B-lymphocytic leukemia ezinesifo esingapheliyo

Izinga le-CR lenyanga enye	Izinga le-PR lenyanga enye	Inyanga enye okanye izinga le-OR	I-CRS≥3	I-CRES≥3
92.1% (35/38)	7.9%（3/38）	100% （38/38）	15.79% (6/38)	0

Iimpawu ze-BCMACAR-T: Unyango lwe-myeloma ephindaphindayo nengasasebenziyo

Izinga le-CR lenyanga enye	Izinga le-PR lenyanga enye	Inyanga enye okanye izinga le-OR	I-CRS≥3	I-CRES≥3
72.41% (21/29)	27.59%（8/29）	100% (29/29)	6.9% (2/29)	0

ISISHWANKATHELO SONYANGO LWE-CAR-T (2)6u3

Kutheni Ukhetha Thina?

Iingenelo Zethu

●Unyango Olulungiselelwe Umntu: Senza ngokwezifiso unyango lwe-CAR-T kwisigulana ngasinye, siqinisekisa unyango olujoliswe kulo nolusebenzayo.

●Iindlela ezahlukeneyo zokuJolisa: Iimveliso zethu ze-CAR-T zibonelela ngeendlela ezahlukeneyo zokuJolisa, kubandakanya i-CD7, i-CD19, i-CD20, i-CD22, kunye ne-BCMA, nto leyo enika ithuba lokukhetha unyango olulungiselelwe izigulane.

●Itekhnoloji yanamhlanje: Unyango lwethu lwe-CAR-T lusebenzisa uphuhliso lwamva nje kubunjineli bemfuza kunye ne-immunotherapy.

●Ukusebenza kakuhle kweendleko: Xa kuthelekiswa nezinye iimveliso, sinikezela ngokulinganisela okuphezulu phakathi kokuqinisekiswa komgangatho kunye namaxabiso akhuphisanayo.

●Ubuchule Kwezonyango: Sixhaswa liqela loogqirha abanamava kunye nabaphandi, sinikezela ngononophelo olusemgangathweni kunye nenkxaso kulo lonke inkqubo yonyango.

●Indlela Epheleleyo: Sinikezela ngononophelo olupheleleyo, ukusuka kuvavanyo lwesigulana ukuya ekunikezelweni konyango kunye nokulandelela, siqinisekisa iziphumo ezilungileyo.