E pili ana i kā mākou huiʻIkepili Lapaʻau CAR-T
Nā hōʻailona o CAR-T
● Leukemia lymphoblastic koʻikoʻi o nā cell B
● Myeloma lehulehu
● Leukemia lymphocytic mau loa
● Lymphoma ʻaʻole Hodgkin
● Lymphoma cell B nui e pālahalaha ana
● SLE（Lupus Erythematosus ʻōnaehana）
Hana maikaʻi loa o ka hana lapaʻau CAR-T
Nā hōʻailona no CD19+20CAR-T: Nā maʻi me ka lymphoma B-cell non Hodgkin
Ka uku CR hoʻokahi mahina | Ka uku PR hoʻokahi mahina | Hoʻokahi mahina OR uku | CRS≥3 | CRES≥3 |
71.95%（59/82） | 25.6（21/82） | 97.55（80/82） | 12.19%（10/82） | 0 |
Nā hōʻailona no CD19+22CAR-T: Ka mālama ʻana i nā maʻi leukemia B-lymphocytic acute i hoʻihoʻi ʻia mai ka CD19 a me ka refractory
Ka uku CR hoʻokahi mahina | Ka uku PR hoʻokahi mahina | Hoʻokahi mahina OR uku | CRS≥3 | CRES≥3 |
92.1%（35/38） | 7.9%（3/38） | 100%（38/38） | 15.79%（6/38） | 0 |
Nā hōʻailona no BCMACAR-T: Ka mālama ʻana i ka myeloma maha relapsed a me ka refractory
Ka uku CR hoʻokahi mahina | Ka uku PR hoʻokahi mahina | Hoʻokahi mahina OR uku | CRS≥3 | CRES≥3 |
72.41%（21/29） | 27.59%（8/29） | 100%（29/29） | 6.9%（2/29） | 0 |
No ke aha e koho ai iā mākou?
Ko mākou mau pono
●Lapaʻau Pilikino: Hoʻopilikino mākou i ka lāʻau lapaʻau CAR-T no kēlā me kēia maʻi, e hōʻoiaʻiʻo ana i ka lāʻau lapaʻau i kuhikuhi ʻia a kūpono hoʻi.
●Nā Koho Hoʻolālā Like ʻOle: Hāʻawi kā mākou huahana CAR-T i kahi ākea o nā koho hoʻolālā, me CD7, CD19, CD20, CD22, a me BCMA, e hāʻawi ana i ka pono o nā koho lapaʻau pilikino no nā mea maʻi.
●ʻEnehana ʻoi loa: Hoʻohana kā mākou lāʻau lapaʻau CAR-T i nā holomua hou loa i ka ʻenekinia genetic a me ka immunotherapy.
●Ka uku kūpono kiʻekiʻe: Ke hoʻohālikelike ʻia me nā huahana ʻē aʻe, hāʻawi mākou i kahi kaulike kiʻekiʻe ma waena o ka hōʻoia maikaʻi a me ke kumukūʻai hoʻokūkū.
●ʻIke Lapaʻau: Kākoʻo ʻia e kahi hui o nā kauka lapaʻau akamai a me nā mea noiʻi, hāʻawi mākou i ka mālama kiʻekiʻe a me ke kākoʻo ma o ke kaʻina hana lapaʻau.
●Ke ʻAno Holoʻokoʻa: Hāʻawi mākou i ka mālama piha, mai ka loiloi ʻana i ka mea maʻi a hiki i ka hoʻokele ʻana i ka lāʻau lapaʻau a me ka hahai ʻana, e hōʻoiaʻiʻo ana i nā hopena kūpono loa.