Zokhudza kampani yathuChidule cha Chithandizo cha CAR-T

CAR-T Therapy, mwachidule Chimeric Antigen Receptor T-Cell Immunotherapy, ndi njira yapamwamba yochiritsira majini yomwe imaphatikizapo kusintha majini a T cells a wodwala kuti awononge maselo a khansa. Mosiyana ndi mankhwala achikhalidwe, CAR-T therapy imapangidwa kwa wodwala aliyense ndipo imafuna kusonkhanitsa maselo a T kuchokera m'magazi a wodwalayo asanawabwezeretse m'thupi pambuyo pa kusintha majini.

CHIDULE CHA CHITHANDIZO CHA CAR-T (1)smn

Fufuzani Zinthu Zake

Zizindikiro za CAR-T

● B-cell acute lymphoblastic leukemia

● Matenda a myeloma ambiri

● Khansa ya m'magazi yosatha

● Matenda a lymphoma omwe si a Hodgkin

● Kufalitsa lymphoma ya maselo akuluakulu a B

● SLE (Systemic Lupus Erythematosus)

Kuchita bwino kwambiri kwachipatala cha CAR-T

Zizindikiro za CD19+20CAR-T: Odwala omwe ali ndi B-cell non Hodgkin's lymphoma

Mtengo wa CR wa mwezi umodzi	Mtengo wa PR wa mwezi umodzi	Mtengo wa OR wa mwezi umodzi	CRS≥3	CRES≥3
71.95% (59/82)	25.6 (21/82)	97.55（80/82）	12.19% (10/82)	0

Zizindikiro za CD19+22CAR-T: Chithandizo cha odwala omwe ali ndi vuto la khansa ya m'magazi ya B-lymphocytic omwe abwereranso ku CD19 komanso omwe ali ndi vuto la kuchepa kwa magazi m'thupi

Mtengo wa CR wa mwezi umodzi	Mtengo wa PR wa mwezi umodzi	Mtengo wa OR wa mwezi umodzi	CRS≥3	CRES≥3
92.1% (35/38)	7.9% (3/38)	100% (38/38)	15.79% (6/38)	0

Zizindikiro za BCMACAR-T: Chithandizo cha myeloma yambiri yobwereranso komanso yokana

Mtengo wa CR wa mwezi umodzi	Mtengo wa PR wa mwezi umodzi	Mtengo wa OR wa mwezi umodzi	CRS≥3	CRES≥3
72.41% (21/29)	27.59% (8/29)	100% (29/29)	6.9% (2/29)	0

CHIDULE CHA CHITHANDIZO CHA CAR-T (2)6u3

Chifukwa Chiyani Sankhani Ife?

Ubwino Wathu

●Chithandizo Chomwe Chimaperekedwa Kwa Munthu Aliyense: Timasintha chithandizo cha CAR-T kwa wodwala aliyense, kuonetsetsa kuti chithandizocho chili ndi cholinga komanso chothandiza.

●Zosankha Zosiyanasiyana Zoganizira: Zogulitsa zathu za CAR-T zimapereka njira zosiyanasiyana zoganizira, kuphatikizapo CD7, CD19, CD20, CD22, ndi BCMA, zomwe zimapereka mwayi wosankha njira zochiritsira zomwe wodwala angagwiritse ntchito payekha.

●Ukadaulo Wamakono: Chithandizo chathu cha CAR-T chimagwiritsa ntchito kupita patsogolo kwaposachedwa mu uinjiniya wa majini ndi chithandizo cha immunotherapy.

●Kugwiritsa ntchito bwino ndalama: Poyerekeza ndi zinthu zina, timapereka mgwirizano wabwino kwambiri pakati pa chitsimikizo cha khalidwe ndi mitengo yopikisana.

●Ukatswiri wa Zachipatala: Mothandizidwa ndi gulu la madokotala ndi ofufuza odziwa bwino ntchito, timapereka chithandizo chapamwamba komanso chithandizo panthawi yonse ya chithandizo.

●Njira Yokwanira: Timapereka chisamaliro chokwanira, kuyambira kuwunika wodwala mpaka kupereka chithandizo ndi kutsatira, kuonetsetsa kuti zotsatira zake ndi zabwino kwambiri.