Nezve kambani yeduOngororo yeKurapa kweCAR-T

CAR-T Therapy, muchidimbu zvinoreva Chimeric Antigen Receptor T-Cell Immunotherapy, inzira yepamusoro yekurapa majini inosanganisira kugadzirisa majini emurwere T masero kuti arwise uye aparadze masero egomarara. Kusiyana nemishonga yechinyakare, CAR-T therapy yakagadzirirwa murwere wega wega uye inoda kuunganidza T masero kubva muropa remurwere asati adzoserwa mumuviri mushure mekugadzirwa kwemajini.

ZVIMWE ZVINOTAURWA NE CAR-T RERAP (1)smn

Ongorora Zvinhu Zviripo

Zviratidzo zveCAR-T

● B-cell acute lymphoblastic leukemia

● Multiple myeloma

● Leukemia isingaperi yelymphocytic

● Lymphoma isiri yeHodgkin

● Kupararira kweB-cell lymphoma yakakura

● SLE (Systemic Lupus Erythematosus)

Kushanda zvakanaka kwekiriniki yeCAR-T

Zviratidzo zveCD19+20CAR-T: Varwere vane B-cell non Hodgkin's lymphoma

Mwedzi mumwe chete CR rate	Mutengo wePR wemwedzi mumwe chete	Mwedzi mumwe chete OR chiyero	CRS≥3	CRES≥3
71.95% (59/82)	25.6 (21/82)	97.55（80/82）	12.19% (10/82)	0

Zviratidzo zveCD19+22CAR-T: Kurapa kwevarwere vane chirwere cheCD19 vane chirwere cheB-lymphocytic leukemia chinodzoka shure uye chisingadzoreki

Mwedzi mumwe chete CR rate	Mutengo wePR wemwedzi mumwe chete	Mwedzi mumwe chete OR chiyero	CRS≥3	CRES≥3
92.1% (35/38)	7.9% (3/38)	100% (38/38)	15.79% (6/38)	0

Zviratidzo zveBCMACAR-T: Kurapa kwe multiple myeloma inodzokera shure uye isingadzoreki

Mwedzi mumwe chete CR rate	Mutengo wePR wemwedzi mumwe chete	Mwedzi mumwe chete OR chiyero	CRS≥3	CRES≥3
72.41% (21/29)	27.59% (8/29)	100% (29/29)	6.9% (2/29)	0

ZVIMWE ZVINOTAURWA NE CAR-T RERAPY (2)6u3

Sei Uchifanira Kusarudza Isu?

Zvakanakira Zvedu

●Kurapwa Kwakasiyana: Tinogadzira kurapa kweCAR-T kumurwere wega wega, tichiona kuti kurapwa kwakanangana uye kunoshanda.

●Sarudzo Dzakasiyana-siyana Dzekutarisa: Zvigadzirwa zvedu zveCAR-T zvinopa sarudzo dzakasiyana-siyana dzekutarisa, dzinosanganisira CD7, CD19, CD20, CD22, uye BCMA, zvichipa mukana wesarudzo dzekurapa dzakagadzirirwa varwere.

●Tekinoroji Yemazuva Ano: Kurapa kwedu kweCAR-T kunoshandisa kufambira mberi kwazvino muinjiniya yemajini uye immunotherapy.

●Kushanda zvakanaka kwemutengo: Kana tichienzanisa nezvimwe zvigadzirwa, tinopa chiyero chakanaka pakati pevimbiso yemhando yepamusoro nemitengo inokwikwidzana.

●Hunyanzvi hwekurapa: Tichitsigirwa nechikwata chevanachiremba nevaongorori vane ruzivo, tinopa rubatsiro rwemhando yepamusoro panguva yese yekurapa.

●Maitiro Akakwana: Tinopa rubatsiro rwakakwana, kubva pakuongororwa kwemurwere kusvika pakupa rubatsiro rwekurapa nekutevera, tichiona kuti mhedzisiro yakanaka.