Mō tā mātou kamupeneTirohanga Whānui mō te Whakaora CAR-T

Ko te CAR-T Therapy, he whakarāpopototanga mō te Chimeric Antigen Receptor T-Cell Immunotherapy, he tikanga whakaora ira matatau e uru ana ki te whakarerekē ira i ngā pūtau-T o te tūroro hei arotahi me te whakangaro i ngā pūtau matepukupuku. He rerekē ki ngā rongoā tuku iho, he mea whakarite te whakaora CAR-T ki ia tūroro, ā, me kohi ngā pūtau-T mai i te toto o te tūroro i mua i te whakahokinga mai ki roto i te tinana i muri i te hangarau ira.

Tūhurahia ngā Āhuatanga

Ngā tohu o CAR-T

● Te mate pukupuku toto nui o te pūtau-B

● Myeloma maha

● Te mate toto totoka mau tonu

● Te mate pukupuku kore-Hodgkin

● Te lymphoma pūtau-B nui horapa

● SLE（Lupus Erythematosus Pūnaha）

He tino pai te mahi haumanu a CAR-T

Ngā tohu mō te CD19+20CAR-T: Ngā tūroro e pāngia ana e te lymphoma kore-pūtau-B a Hodgkin

Reiti CR kotahi marama	Te utu PR kotahi marama	Kotahi marama OR reiti	CRS≥3	CRES≥3
71.95%（59/82）	25.6（21/82）	97.55（80/82）	12.19%（10/82）	0

Ngā tohu mō te CD19+22CAR-T: Te maimoatanga o ngā tūroro mate pukupuku toto B-lymphocytic whakapeka kua hoki mai te CD19 me te uaua ki te mahi

Reiti CR kotahi marama	Te utu PR kotahi marama	Kotahi marama OR reiti	CRS≥3	CRES≥3
92.1%（35/38）	7.9%（3/38）	100%（38/38）	15.79%（6/38）	0

Ngā tohu mō te BCMACAR-T: Te maimoatanga o te myeloma maha kua hoki mai me te uaua ki te whakatika

Reiti CR kotahi marama	Te utu PR kotahi marama	Kotahi marama OR reiti	CRS≥3	CRES≥3
72.41%（21/29）	27.59%（8/29）	100%（29/29）	6.9%（2/29）	0

He aha mātou i whiriwhiri ai?

Ā Mātou Painga

●Maimoatanga Whaiaro: Ka whakaritea e mātou te rongoā CAR-T mō ia tūroro, kia tika ai te maimoatanga, kia whai hua ai hoki.

●Ngā Kōwhiringa Whāinga Kanorau: He whānuitanga o ngā kōwhiringa ūnga kei roto i ā mātou hua CAR-T, tae atu ki te CD7, CD19, CD20, CD22, me te BCMA, e whakarato ana i te painga o ngā kōwhiringa maimoatanga whaiaro mō ngā tūroro.

●Hangarau Hou: E whakamahia ana e tā mātou rongoā CAR-T ngā whanaketanga hou o te hangarau ira me te rongoā ārai mate.

●Te utu-whai hua nui: Ki te whakatauritea ki ētahi atu hua, he pai ake te taurite i waenga i te kounga me te utu whakataetae.

●Tohungatanga Hauora: Me te tautoko a tētahi rōpū tākuta me ngā kairangahau mātau, ka tukuna e mātou te tiaki me te tautoko kounga teitei puta noa i te tukanga maimoatanga.

●Huarahi Whānui: Ka tukuna e mātou he manaakitanga whānui, mai i te aromatawai i te tūroro ki te whakahaere i te rongoā me te whai i ngā mahi, kia tino pai ai ngā putanga.