Txog peb lub tuam txhabKev Txheeb Xyuas Txog Kev Kho Mob CAR-T

CAR-T Therapy, luv rau Chimeric Antigen Receptor T-Cell Immunotherapy, yog ib txoj kev kho mob gene siab heev uas cuam tshuam txog kev hloov kho tus neeg mob cov T cell kom tsom mus rau thiab rhuav tshem cov cell mob qog noj ntshav. Tsis zoo li cov tshuaj ib txwm muaj, CAR-T therapy yog tsim rau txhua tus neeg mob thiab yuav tsum tau sau cov T cell los ntawm tus neeg mob cov ntshav ua ntej rov muab lawv rov qab rau hauv lub cev tom qab kev kho genetic engineering.

Kev Txheeb Xyuas Txog Kev Kho Mob CAR-T (1)smn

Tshawb Nrhiav Cov Nta

Cov cim qhia ntawm CAR-T

● B-cell leukemia mob lymphoblastic mob hnyav

● Mob qog nqaij hlav ntau yam

● Kab mob leukemia lymphocytic ntev

● Lymphoma uas tsis yog Hodgkin

● Cov kab mob B-cell lymphoma loj uas kis tau rau lwm qhov

● SLE (Systemic Lupus Erythematosus)

Kev ua haujlwm zoo heev ntawm CAR-T hauv kev kho mob

Cov cim qhia rau CD19 + 20CAR-T: Cov neeg mob uas muaj B-cell non Hodgkin's lymphoma

Tus nqi CR ib hlis	Tus nqi PR ib hlis	Tus nqi ib hlis LOS YOG	CRS≥3	CRES≥3
71.95% (59/82)	25.6 (21/82)	97.55 (80/82)	12.19% (10/82)	0

Cov cim qhia rau CD19 + 22CAR-T: Kev kho mob ntawm cov neeg mob CD19 uas rov qab mob dua thiab tsis kho tau kab mob B-lymphocytic leukemia

Tus nqi CR ib hlis	Tus nqi PR ib hlis	Tus nqi ib hlis LOS YOG	CRS≥3	CRES≥3
92.1% (35/38)	7.9% (3/38)	100% (38/38)	15.79% (6/38)	0

Cov cim qhia rau BCMACAR-T: Kev kho mob ntawm cov mob multiple myeloma uas rov tshwm sim thiab tsis kho tau

Tus nqi CR ib hlis	Tus nqi PR ib hlis	Tus nqi ib hlis LOS YOG	CRS≥3	CRES≥3
72.41% (21/29)	27.59% (8/29)	100% (29/29)	6.9% (2/29)	0

Kev Txheeb Xyuas Txog Kev Kho Mob CAR-T (2)6u3

Vim li cas ho xaiv peb?

Peb Qhov Zoo

●Kev Kho Mob Rau Tus Kheej: Peb kho CAR-T kev kho mob rau txhua tus neeg mob, kom ntseeg tau tias kev kho mob raug tsom mus rau qhov tseeb thiab zoo.

●Kev Xaiv Ntau Hom Phiaj: Peb cov khoom CAR-T muaj ntau hom phiaj xaiv, suav nrog CD7, CD19, CD20, CD22, thiab BCMA, muab qhov zoo ntawm kev xaiv kev kho mob rau cov neeg mob.

●Kev Siv Tshuab Tshiab: Peb txoj kev kho mob CAR-T siv cov kev nce qib tshiab kawg hauv kev tsim kho caj ces thiab kev kho mob tiv thaiv kab mob.

●Kev siv nyiaj tsim nyog: Piv rau lwm cov khoom, peb muab kev sib npaug zoo dua ntawm kev lees paub zoo thiab kev sib tw nqi.

●Kev Paub Txog Kev Kho Mob: Peb muaj pab pawg kws kho mob thiab cov kws tshawb fawb uas muaj kev paub dhau los, thiab peb muab kev saib xyuas zoo thiab kev txhawb nqa thoob plaws hauv kev kho mob.

●Kev Kho Mob Kom Zoo: Peb muab kev kho mob kom zoo, txij li kev ntsuam xyuas tus neeg mob mus txog kev tswj hwm kev kho mob thiab kev saib xyuas tom qab, kom ntseeg tau tias muaj txiaj ntsig zoo tshaj plaws.