Indaba Yesiguli: Kusukela Ekuxilongweni kwe-AML-M2 Kuya Kumuntu Osanda Kuqala Eyunivesithi - Uhambo Lweminyaka Emihlanu Lokululama

Ehlobo lika-2015, umfana oneminyaka engu-12 ubudala ogama lakhe linguMingming (alias) watholakala ene-acute myeloid leukemia (AML-M2). Okwakufanele kube isikhathi sokukhululeka ebangeni lesithupha kwaphenduka uhambo olunzima lokwelashwa, ukuhlala esibhedlela, kanye nokuzimisela okungapheli. Namuhla, eminyakeni emihlanu ngemva kokufakelwa, uMingming akagcinanga ngokuthola ukuphulukiswa kodwa futhi ugcwalise iphupho lakhe lokungena eyunivesithi.

Ukuxilongwa Okubuhlungu Nokufuna Ithemba

Izimpawu zokuqala zikaMingming, okuhlanganisa ubuhlungu bamathambo kanye nokudumba okubonakalayo, kwaholela ekuxilongweni okushaqisayo kwe-AML-M2. Umndeni wakhe, ohlala esifundeni esincane eXinjiang, waqala uhambo olunzima oluvela kwesinye isibhedlela uya kwesinye ufuna ukwelashwa okuphumelelayo. Impi yayigcwele izinselele zomzimba nezingokomzwelo, njengoba imijikelezo ye-chemotherapy yayimqeda amandla yena nomndeni wakhe. Naphezu kokuthola ukuphulukiswa okuyingxenye kwesimo somzimba, i-AML1-ETO fusion gene yahlala itholakala, okubonisa impendulo engaphelele.

Isiqalo Esisha Esibhedlela iLu Daopei

NgoJuni 2016, uMingming nomndeni wakhe bafika eSibhedlela iLu Daopei. Ngemva kokuhlolwa okuphelele, ithimba lezokwelapha, eliholwa nguDkt. Zhou Jarui noDkt. Wang Jingyu, lancoma ukufakelwa iseli le-hematopoietic stem cell elisebenzisa uyise njengomnikeli. Ukunakekelwa okucophelelayo kanye nobuchwepheshe bethimba lokufakelwa kwafaka ithemba elisha nesibindi kuMingming nomndeni wakhe.

Inqubo yokufakelwa isilwane yayinzima. UMingming wabhekana nezinkinga, okuhlanganisa nesifo sesibindi kanye nesikhumba esifakwe i-graft-versus-host (GVHD) kanye nokutheleleka kwe-cytomegalovirus (CMV). Kodwa-ke, ukunakekelwa kobungcweti nozwela kweqembu kwamsiza ukuba anqobe lezi zithiyo. Ngo-2018, i-allogeneic chimerism yaqinisekiswa ngo-100%, futhi lesi sifo sahlala sikhululekile ngesikhathi sokulandelela.

Iphupho Elifezekile

Manje, eminyakeni emihlanu ngemva kokufakelwa, impilo kaMingming iyaqhubeka nokuchuma, futhi usewufezile umgomo wakhe wokufunda eyunivesithi. Ecabanga ngohambo lwakhe, ubonga kakhulu umndeni wakhe, abasebenzi bezokwelapha abazinikele eSibhedlela iLu Daopei, kanye nomphakathi obanzi owamsekela. Indaba kaMingming iyisiqiniseko sokuqina kanye namandla okunakekelwa kwezokwelapha okuthuthukile ekuguquleni izimpilo.

Isigijimi Sethemba

Kulabo abasabhekene nezifo ezifanayo, uMingming uyabelana:
"Ungesabi. Yiba nesibindi uqhubekele phambili. Awuwedwa kule mpi. Ngemuva kwakho akukhona nje umndeni wakho kodwa futhi nochwepheshe bezokwelapha abaningi kanye nabantu abakhathalela kakhulu ukululama kwakho. Sisonke, singanqoba ubumnyama bokugula futhi samukele ukukhanya kokuphila."