Ibali lesigulana: Ukusuka kwi-AML-M2 Diagnosis ukuya kwi-Wintern yaseYunivesithi – Uhambo lweminyaka emihlanu oluya ekuPhileni

Ehlotyeni lowama-2015, inkwenkwe eneminyaka eli-12 ubudala egama linguMingming (alias) yafunyaniswa ukuba ine-acute myeloid leukemia (AML-M2). Ixesha ebelifanele ukuba lilo lokuphumla kwibanga lesithandathu lajika laba luhambo olunzima lonyango, ukuhlala esibhedlele, kunye nokuzimisela okungapheliyo. Namhlanje, emva kweminyaka emihlanu emva kokufakelwa isibeleko, uMingming akafumananga nje kuphela ukuxolelwa kodwa ukwazalisekisa iphupha lakhe lokungena eyunivesithi.

Uxilongo Olubuhlungu Nokufuna Ithemba

Iimpawu zokuqala zikaMingming, kuquka iintlungu zamathambo kunye nokudumba okubonakalayo, zakhokelela ekuxilongweni okumangalisayo kwe-AML-M2. Usapho lwakhe, oluhlala kwisithili esincinci eXinjiang, lwaqalisa uhambo olunzima ukusuka kwesinye isibhedlele ukuya kwesinye lufuna unyango olusebenzayo. Idabi lalizele yimingeni yomzimba neyeemvakalelo, njengoko imijikelo ye-chemotherapy yayimdinisa yena nosapho lwakhe. Nangona befumana ukukhululwa okuncinci kwesimo somzimba, i-AML1-ETO fusion gene yahlala ibonwa, nto leyo ebonisa impendulo engaphelelanga.

Isiqalo Esitsha kwiSibhedlele iLu Daopei

NgoJuni 2016, uMingming kunye nosapho lwakhe bafika kwiSibhedlele iLu Daopei. Emva kovavanyo olucokisekileyo, iqela lezonyango, elikhokelwa nguGqr. Zhou Jarui kunye noGqr. Wang Jingyu, lacebisa ukufakelwa i-haploidentical hematopoietic stem cell esebenzisa uyise njengomxhasi. Ukunyamekela okucokisekileyo kunye nobuchule beqela lokufakelwa kwafaka ithemba elitsha kunye nesibindi kuMingming nosapho lwakhe.

Inkqubo yokufakelwa isidoda yayinzima. UMingming wajongana neengxaki, kuquka isifo sesibindi kunye nesifo sokufakelwa kwesidoda (GVHD) kunye nosulelo lwe-cytomegalovirus (CMV). Nangona kunjalo, inkathalo yobungcali kunye novelwano lweqela lwamnceda ukuba oyise le miqobo. Ngo-2018, i-allogeneic chimerism yaqinisekiswa kwi-100%, kwaye esi sifo sahlala silungile ngexesha lokulandelela.

Iphupha Elizalisekileyo

Ngoku, emva kweminyaka emihlanu emva kokufakelwa isitho, impilo kaMingming iyaqhubeka nokukhula, kwaye ufezekisile usukelo lwakhe lokufunda eyunivesithi. Ecinga ngohambo lwakhe, ubulela kakhulu usapho lwakhe, abasebenzi bezonyango abazinikeleyo kwiSibhedlele iLu Daopei, kunye noluntu olubanzi olumxhase. Ibali likaMingming libubungqina bokuqina kunye namandla onyango oluphambili ekuguquleni ubomi.

Isigidimi Sethemba

Kwabo basalwa nezigulo ezifanayo, uMingming uthi:
"Musa ukoyika. Yiba nesibindi kwaye uqhubeke phambili. Awuwedwa kulo mlo. Emva kwakho akukho sapho lwakho kuphela kodwa kukho neengcali zonyango ezingenakubalwa kunye nabantu abakukhathaleleyo kakhulu ukuchacha kwakho. Sisonke, singaboyisa ubumnyama bokugula size samkele ukukhanya kobomi."