A determined man from India battles gastric cancer

There is a resilient man named Thirandas Shiva Prasad. He’s 32 years old, and he comes from India. Why do we highlight his determination? Here is his remarkable story.

Thirandas was diagnosed with gastric cancer in 2023, presenting with abdominal pain and confirmed as low-grade signet ring cell adenocarcinoma. He underwent neoadjuvant chemotherapy with FLOT regimen, followed by surgery including subtotal gastrectomy. Despite postoperative treatments, the cancer recurred with metastases to the pelvis, causing complications like hydronephrosis, abscesses, and obstructions. He endured multiple interventions, including dialysis, stenting, and further chemo with nab-paclitaxel, nivolumab, irinotecan, and others. By 2025, PET-CT scans showed progression with increased abdominal lesions and ascites, leaving him in need of innovative options.

Seeking cutting-edge care, Thirandas turned to BIOOCUS. Our expert team offered a free initial assessment, reviewing his extensive history and recommending CLDN18.2 CAR-T cell therapy, tailored to his tumor's expression. After preconditioning, the infusion was performed smoothly in our advanced facility. Despite initial challenges like fever and potential infection, our multidisciplinary team managed symptoms effectively with antibiotics and supportive care, ensuring no severe CRS. Procedures like abdominal drainage and stent adjustments were handled with precision, leading to symptom relief and positive pathology results post-treatment.

BIOOCUS stands out for its superior service and innovative products. Our CAR-T therapy, targeting CLDN18.2, provides a targeted attack on cancer cells, often succeeding where conventional therapies fail. The patient services excel in coordinating international travel, providing cultural sensitivity, and offering comprehensive follow-up, all at no extra burden. Thirandas appreciates the empathetic staff and efficient processes that turned a daunting experience into one of hope.