Lymphoma nini ya B-cell (DLBCL) ikwirakwira mu maraso

Uwo murwayi, umugore w’intwari uri hafi y’imyaka 80, yahuye n’ubutwari bwo gusuzuma indwara ya Diffuse Large B-cell Lymphoma (DLBCL), agaragaza ubutwari butangaje mu rugamba rwe rwo kurwanya iyi kanseri ikomeye.

Nubwo yari ageze mu za bukuru, yakomeje kwiyemeza guhangana n’ibibazo byaterwaga n’uburwayi bwe. Ariko, mu mezi atandatu nyuma yo koroherwa n’ubuvuzi bwa mbere, yongeye kurwara, bigaragaza ko indwara ye yari ikomeye cyane. Nubwo yagerageje kenshi kuvura bwa kabiri n’ubwa gatatu, kanseri ye yagaragaje ubudahangarwa bukomeye, iteza imbogamizi ikomeye ku ikipe ye y’abaganga.

Itsinda ry’abaganga rimaze kubona ko ikibazo cye cyihutirwa, ryatangiye ubushakashatsi bwo gushakisha ubundi buryo bwo kuvura. Uyu murwayi yashyizwe mu igerageza ryakozwe ku buvuzi bwa CD19+22 CAR-T cell therapy, uburyo bugezweho bukoresha uturemangingo twa T twahinduwe mu buryo bw’uturemangingo kugira ngo twibasire uturemangingo twa kanseri tugaragaza antigens runaka.

Ibisubizo byari bitangaje cyane. Nyuma y'ukwezi kumwe gusa ahawe uturemangingo twa CD19+22 CAR-T, umurwayi yakize burundu. Iyi ngaruka ikomeye ntiyahagaritse gusa iterambere ry'indwara ye ahubwo yanatumye uturemangingo twa kanseri turarandurwa neza, biba ibihe by'ingenzi mu rugendo rwe rwo kuvurwa.

Mu gihe cyose cy’urugendo rurerure, itsinda ry’abaganga ryatanze ubufasha n’ubuvuzi budasubirwaho ku murwayi. Kuva mu gukurikiranira hafi uko yakiraga ubuvuzi kugeza ku guhangana n’ingaruka mbi, bashyize imbere imibereho myiza ye.

Atekereje ku byo yabonye, ​​umurwayi yashimiye cyane ubuvuzi bwe bw’impuhwe yahawe. Yagize ati: "Ubwitange n'ubuhanga bw'ikipe yanjye y'abaganga byari bidasanzwe rwose." "Uburyo bwabo bwihariye bwo kuvura bwampaye icyizere igihe nari nkeneye cyane."

Umusaruro mwiza wavuye mu buvuzi bwa CD19+22 CAR-T cells mu kugera ku ndunduro yuzuye ugaragaza ko ari uburyo bwiza bwo kuvura abarwayi ba DLBCL barwaye indwara idakira. Iki kibazo ni igihamya cy'imbaraga z'ubuvuzi bushya n'ubuvuzi bwihariye mu kuvura kanseri zikomeye, cyane cyane ku barwayi bageze mu za bukuru nk'uyu mugore w'intwari.

Mbere na nyuma y'ukwezi kumwe guterwa