Lymphoma nini ya B-cell (DLBCL), NOS, ubwoko bwa GCB, lymphoma y'imitsi yo mu mutwe y'ibanze-01

Mu Kuboza 2019, Bwana Wang, umwarimu wo mu Majyaruguru y'Ubushinwa, yatangiye kurwara umutwe. Ku ya 19 Ukuboza 2019, ibizamini byo gusuzuma byagaragaje ibi bikurikira: PET-CT yagaragaje igicucu cy'ubucucike hamwe n'ubwiyongere bukabije bwa FDG mu gice cy'ibumoso cy'imbere n'agace k'ivi rya corpus callosum (hafi 3.4 * 1.9 cm, SUVmax = 34.4). Biopsy na immunohistochemistry byemeje ko lymphoma nini ya B-cell (DLBCL, NOS, GCB subtype), hamwe n'ubwoko bwa immunophenotype igaragaza Ki67 (50% +), CD19 (+), CD20 (+), PAX5 (+), CD79 (+), MUM1 (+), BCL (+), CD10 (-/+), CD2 (minor +). Isesengura ry'amazi yo mu bwonko ryagaragaje 6% by'uturemangingo tw'ubwonko tudakuze dufite imiterere itandukanye. Isuzuma ryakozwe ni lymphoma y'imitsi yo mu mutwe (DLBCL, GCB subtype).

Nyuma yo gukora ubushakashatsi ku buryo bwo kuvura kuri interineti, Bwana Wang yize ku bushobozi bwa BIOOCUS Medical Group mu kuvura indwara z’umubiri maze ahita ashaka ubumenyi bwabo. Nyuma yo gusuzuma neza umubiri no gusesengura neza kw’itsinda ry’inzobere mu bitaro, hafashwe icyemezo cy’uko Bwana Wang azitabira igerageza rya CART therapy, cyane cyane hakoreshejwe uturemangingo twa CD19 CART. Yahawe autologous CD19 CAR-T cells ku ya 24 Mata 2023. Ku ya 30 Nyakanga 2023, byagaragaye ko yageze ku buremere bwuzuye (CR) kandi kuva icyo gihe yasubiye mu buzima busanzwe.