Yaɗuwar babban lymphoma na B-cell (DLBCL), NOS, nau'in GCB, babban tsarin juyayi na tsakiya lymphoma-01

A watan Disamba na 2019, Mista Wang, wani malami daga Arewa maso Gabashin China, ya fara fuskantar ciwon kai. A ranar 19 ga Disamba, 2019, gwaje-gwajen bincike sun nuna kamar haka: PET-CT ta nuna inuwar yawa tare da ƙaruwar metabolism na FDG a yankin gefen hagu na gaba da kuma yankin gwiwa na corpus callosum (kimanin 3.4 * 1.9 cm, SUVmax = 34.4). Biopsy da immunohistochemistry sun tabbatar da yaduwar babban lymphoma na B-cell (DLBCL, NOS, nau'in GCB), tare da immunophenotype wanda ke nuna Ki67(50%+), CD19(+), CD20(+), PAX5(+), CD79(+), MUM1(+), BCL(+), CD10(-/+), CD2(ƙananan+). Binciken ruwan Cerebrospinal ya nuna kashi 6% na ƙwayoyin lymphoid marasa girma tare da bambancin siffa. An gano cutar lymphoma na tsarin jijiyoyi na tsakiya (DLBCL, nau'in GCB).

Bayan ya yi bincike kan hanyoyin magani ta intanet, Mista Wang ya sami labarin ƙwarewar maganin rigakafi na BIOOCUS Medical Group kuma nan take ya nemi ƙwarewarsa. Bayan cikakken binciken jiki da kuma cikakken bincike daga ƙungiyar ƙwararrun asibitin, an yanke shawarar cewa Mista Wang zai shiga cikin gwajin asibiti don maganin CART, musamman ta amfani da ƙwayoyin CD19 CART. Ya sami maganin ƙwayoyin cuta na CD19 CAR-T a ranar 24 ga Afrilu, 2023. Nan da ranar 30 ga Yuli, 2023, an tantance cewa ya sami cikakkiyar gafara (CR) kuma tun daga lokacin ya dawo cikin rayuwa ta yau da kullun.