Yaɗuwar babban ƙwayar cutar B-cell lymphoma (DLBCL)-03

A watan Maris na 2021, Mista Wang (wanda aka rubuta da sunan karya) ya ji ciwon ciki na ƙasan dama, wanda da farko aka yi masa zaton rashin jin daɗin ciki ne, kuma bai nemi taimakon likita da wuri ba. A cikin watanni biyu da suka biyo baya, ya sha fama da alamun ciwon ciki na ƙasan dama, wanda hakan ya sa ya nemi shawarar likita a wani asibiti na yankin. An nuna wani hoton CT da aka ɗauka a kan hanji da kuma girman ƙwayoyin lymph na retroperitoneal.

Likitoci sun ba da shawarar yin gwajin colonoscopy da biopsy don ƙarin ganewar asali, wanda ya tabbatar da "yaɗuwar babban lymphoma na ƙwayoyin B," wani mummunan ƙari da aka fi sani da lymphoma. PET-CT ta ƙara tabbatar da yaduwar raunuka masu yawa a cikin nodular a cikin jikinsa, tare da mafi girman girman 4.3*4.1*4.5cm.

Tare da goyon bayan iyalinsa, Mista Wang ya yi gwajin maganin R-CHOP sau huɗu. Bayan an yi masa gwajin PET-CT, an gano cewa ya sami sassauci kaɗan.

Duk da haka, magungunan da aka yi daga baya sun haifar da matsaloli masu tsanani ga Mista Wang, kamar toshewar hanji, toshewar hanji, da kuma ciwon ciki mai tsanani. Likitocin tiyata na hanji da likitocin da ke kula da shi sun haɗu kan wani shiri na tiyata, suna yin tiyatar cire hanji da magudanar ruwa, tare da kula da alamun cutar, ta yadda za a iya magance alamun cutar cikin hanjinsa yadda ya kamata.

Bayan gwajin PET-CT, an gano ƙaruwar raunuka da girman ƙari. Domin kawar da ƙwayoyin ƙari mafi kyau, likitoci sun daidaita tsarin maganin chemotherapy mai ƙarfi kuma sun ba da shawarar dashen ƙwayoyin halitta na hematopoietic.

Bayan ya fuskanci matsaloli da dama, Mista Wang ya fuskanci matsaloli na jiki da na motsin rai masu yawa yayin da yanayinsa ke ta'azzara. An lura da shigar ƙari a wurare da dama, inda sabbin raunukan da suka bunƙasa a cikin ƙwayoyin halittar jiki suka faɗaɗa yankin da ke fama da ciwon daji sosai. Saboda ciwon da ke cikin jikinsa, Mista Wang ya sha fama da ciwon jiki na yau da kullun, wanda hakan ya sa ya yi masa wahala ya kwanta ya yi barci saboda ciwo.

Cikin damuwa, Mista Wang ya koyi game da maganin CAR-T, wani sabon maganin rigakafi na ƙwayoyin CAR-T wanda aka tsara musamman ga marasa lafiya da ke fama da cutar lymphoma ta B-cell da ta sake dawowa ko kuma ta sake yin illa.

Kafin a yi wa Ms. Wang maganin CAR-T, an yi masa gwajin ƙwayoyin lymph a yankin hancin dama, wanda ya nuna cewa yana da kyau ga CD19 da CD20, wanda hakan ya samar da takamaiman maƙasudai na maganin ƙwayoyin CAR-T. Farfesa Yu ya shirya cikakken bincike na jiki, wanda ya kai ga ƙirƙirar wani tsarin magani na musamman ga Ms. Wang.

A ranar 25 ga Yuli, 2022, Mista Wang ya karɓi maganin CD19/20 CAR-T cell a asibiti, inda aikin ya tafi cikin sauƙi. Kulawa sosai da kuma kulawa mai ƙarfi ta hanyar da ta dace ta shawo kan munanan halayen bayan an yi wa allurar ba tare da wata matsala mai barazana ga rayuwa ba.

A cikin ƙasa da watanni uku, kafin ranar 10 ga Oktoba, 2022, wani gwajin PET-CT da aka yi masa ya tabbatar da warkewarsa gaba ɗaya, tare da kimantawa gabaɗaya da ke nuna cewa an samu ci gaba sosai a lafiyarsa.

A lokacin da ake bin diddigin lamarin, Mr. Wang ya saba yin gwajin CT, MRI, ko PET-CT akai-akai, duk sun tabbatar da cewa yana da cikakkiyar lafiyar da ta dace. A halin yanzu, lafiyarsa tana nan lafiya, inda ta wuce lokacin da aka yi masa tiyata na tsawon watanni 14.