Lymphoma Pūtau-B Nui Marara (DLBCL)

Ko te tūroro, he wahine manawanui e tata ana ki te 80 tau te pakeke, i tū atu ki te tātaritanga o te mate pukupuku Diffuse Large B-cell Lymphoma (DLBCL), i whakaatu i te maia whakamiharo i roto i tana pakanga ki tēnei momo mate pukupuku kaha.

Ahakoa tōna kaumātuatanga, i kaha tonu ia ki te wikitoria i ngā wero i pā mai i tōna āhua. Heoi, i roto i ngā marama e ono i muri i te whakaoranga me te rongoā raina tuatahi, ka hoki anō ia ki te mate, e whakaatu ana i te kaha o tōna mate. Ahakoa ngā whakamātautau maha me ngā maimoatanga raina tuarua me te tuatoru, i whakaatu tōna mate pukupuku i te ātete pakari, he wero nui tēnei mō tana tīma hauora.

I te mōhio ki te tere o tōna āhuatanga, ka tīmata te tīma hauora ki te tūhura i ngā huarahi maimoatanga rerekē. I whakaurua te tūroro ki tētahi whakamātautau haumanu e tirotiro ana i te rongoā pūtau CD19+22 CAR-T, he huarahi hou e whakamahi ana i ngā pūtau-T i hangaia ira hei aro ki ngā pūtau matepukupuku e whakaatu ana i ngā antigens motuhake.

He tino mīharo ngā hua. Kotahi marama noa iho i muri i te werohanga o ngā pūtau CD19+22 CAR-T, ka tino ora te tūroro. Nā tēnei hua hou, kāore i mutu noa te haere whakamua o tōna mate, engari i ārahi anō hoki ki te whakakorenga angitu o ngā pūtau matepukupuku, he wā tino nui tēnei i roto i tana haerenga maimoatanga.

I roto i te tukanga uaua, i tautoko tonu te tīma hauora i te tūroro, ā, i manaaki hoki i a ia. Mai i te aroturuki tata i tana urupare ki te rongoā tae atu ki te whakahaere i ngā pānga kino, i whakarite kia noho tonu tōna oranga hei kaupapa matua.

I a ia e whakaaroaro ana ki tana wheako, i whakapuaki te tūroro i tōna mihi nui mō te manaakitanga aroha i whakawhiwhia ki a ia. "He tino mīharo te whakapau kaha me te tohungatanga o taku tīma hauora," tana kī. "Nā tā rātou huarahi whaiaro ki te maimoatanga i homai he tumanako ki ahau i te wā i tino hiahiatia ai e au."

Ko te hua angitu o te rongoā pūtau CD19+22 CAR-T ki te whakatutuki i te murunga katoa e whakaatu ana i tōna pūmanawa hei kōwhiringa maimoatanga whai hua mō ngā tūroro DLBCL uaua. He tohu tēnei kēhi i te mana o ngā rongoā auaha me te rongoā whaiaro ki te whakahaere i ngā mate pukupuku uaua, inā koa i roto i ngā tūroro kaumātua pēnei i tēnei wahine toa.

I mua me te 1 marama i muri i te werohanga