Myasthenia gravis-02

Labarin Maganin Myasthenia Gravis na Li Ming

Li Ming, wani malami mai shekaru 35, ya fara fuskantar alamun myasthenia gravis (MG) shekaru uku da suka gabata. Da farko, ya lura da ptosis (faɗuwar ido) da wahalar magana, amma alamun sun ci gaba da ƙaruwa zuwa ga raunin tsoka gabaɗaya, wanda hakan ya sa ayyukan yau da kullun suka zama ƙalubale. Duk da shan magunguna daban-daban, ciki har da steroids da immunosuppressants, alamunsa ba su da tabbas.

Ta hanyar gabatarwar wani abokinsa, Li Ming ya isa BIOOCUS Medical Group don shiga cikin gwajin asibiti na CAR-T. Wata ƙungiyar ƙwararru ta gudanar da cikakken bincike kan alamun cutar kuma ta shirya shi don maganin CAR-T.

Tsarin Magani:

1. Matakin Shiri: Kafin a fara magani, Li Ming ya yi cikakken bincike kan lafiya. Likitoci sun ware ƙwayoyin T daga jikinsa kuma suka gyara su ta hanyar kwayoyin halitta a dakin gwaje-gwaje don bayyana masu karɓar ƙwayoyin cuta na chimeric antigen (CAR) waɗanda ke niyya ga takamaiman ƙwayoyin cuta da ke da alaƙa da myasthenia gravis.

2. Faɗaɗa ƙwayoyin halitta: An faɗaɗa ƙwayoyin CAR-T da aka gyara a dakin gwaje-gwaje don tabbatar da isasshen adadin magani.

3. Gyaran Jiki Kafin a yi amfani da maganin Chemotherapy: Kafin a yi amfani da kwayoyin halittar CAR-T, Li Ming ya yi amfani da maganin chemotherapy na tsawon mako guda don rage yawan lymphocytes da ke jikinsa, wanda hakan ya samar da yanayi mafi kyau ga kwayoyin halittar CAR-T su yi aiki yadda ya kamata.

4. Jikowar Kwayoyin CAR-T: Bayan kammala maganin chemotherapy, an kwantar da Li Ming a asibiti don a yi masa jikowar ƙwayoyin CAR-T. An gudanar da wannan tsari a ƙarƙashin sa ido mai tsauri don hana yiwuwar illa.

Sakamakon Magani:

1. Amsawa ta ɗan gajeren lokaci: A makon farko bayan allurar, Li Ming ya fuskanci zazzabi mai sauƙi da gajiya, alamun da aka saba gani a lokacin maganin ƙwayoyin CAR-T. Makonni biyu bayan haka, matsalar numfashi da wahalar magana sun inganta sosai, kuma ƙarfinsa ya fara dawowa.

2. Ingantaccen Tsarin Aiki na Tsakiyar Lokaci: Bayan watanni biyu, alamun Li Ming sun ragu sosai. Ya sami damar ci gaba da ayyukan koyarwa na yau da kullun, ingantaccen aikinsa ya inganta, kuma ingancin rayuwarsa ya nuna ci gaba sosai.

3. Illolin Na Dogon Lokaci: Watanni uku bayan an yi masa magani, Li Ming bai sake dogara da magungunan da aka yi masa a baya ba. Gwaje-gwajen da aka yi masa sun nuna cewa garkuwar jikinsa tana cikin koshin lafiya, ba tare da an ga wata mummunar illa ba.

Ta hanyar maganin ƙwayoyin cuta na CAR-T, an shawo kan cutar myasthenia gravis ta Li Ming sosai. "Ina matukar godiya ga maganin CAR-T da kuma ƙungiyar likitoci masu himma bisa ƙoƙarinsu," in ji Li Ming cikin hawaye, yana girgiza hannun likitan bayan an sallame shi.