ʻO ka Myasthenia gravis-02

Ka Moʻolelo Lapaʻau no ka Myasthenia Gravis a Li Ming

Ua hoʻomaka ʻo Li Ming, he kumu aʻo 35 makahiki, e ʻike i nā hōʻailona o ka myasthenia gravis (MG) ʻekolu makahiki i hala. I ka wā mua, ua ʻike ʻo ia i ka ptosis (nā maka e hāʻule ana) a me ka paʻakikī o ka ʻōlelo ʻana, akā ua holomua mālie nā hōʻailona i ka nāwaliwali o nā ʻiʻo, e hoʻolilo ana i nā hana o kēlā me kēia lā i mea paʻakikī. ʻOiai ke hana ʻia nei nā ʻano lāʻau like ʻole, me nā steroids a me nā immunosuppressants, ua mau kāna mau hōʻailona me ka ʻole o ka hoʻomalu ʻia.

Ma o ka hoʻolauna ʻana a kahi hoaaloha, ua hōʻea ʻo Li Ming i BIOOCUS Medical Group e komo i kahi hoʻokolohua lapaʻau CAR-T. Ua hana kahi hui o nā loea i kahi loiloi kikoʻī o kāna mau hōʻailona a hoʻomākaukau iā ia no ka lāʻau lapaʻau CAR-T.

Kaʻina Hana Lapaʻau:

1. Ka Papa Hoʻomākaukau: Ma mua o ka mālama ʻana, ua hana ʻia ʻo Li Ming i kahi loiloi olakino piha. Ua hoʻokaʻawale nā ​​​​kauka i nā cell T mai kona kino a hoʻololi i ka genetically iā lākou i loko o ka hale hana e hōʻike i nā mea loaʻa antigen chimeric (CAR) e kuhikuhi ana i nā antigens kikoʻī e pili ana me ka myasthenia gravis.

2. Hoʻonui ʻia ʻana o ke Kelepona: Ua hoʻonui ʻia nā pūnaewele CAR-T i hoʻololi ʻia i loko o ka hale hana hoʻokolohua e hōʻoia i ka lawa ʻana o ka helu no ka mālama ʻana.

3. Ke Hoʻomaʻamaʻa mua ʻana i ka Chemotherapy: Ma mua o ka hoʻokomo ʻana o nā cell CAR-T, ua hana ʻo Li Ming i kahi papa hana chemotherapy no hoʻokahi pule e hōʻemi i ka helu o nā lymphocytes i loko o kona kino, e hana ana i kahi kūlana maikaʻi aʻe no nā cell CAR-T e hana pono.

4. Hoʻokomo ʻia ʻana o ke Kelepona CAR-T: Ma hope o ka pau ʻana o ka chemotherapy, ua hoʻokomo ʻia ʻo Li Ming i ka haukapila e loaʻa i ka hoʻokomo ʻia ʻana o ke kelepona CAR-T. Ua mālama ʻia kēia kaʻina hana ma lalo o ka nānā pono ʻana e pale aku i nā hopena ʻaoʻao.

Nā Hopena Lapaʻau:

1. Pane Pōkole: I ka pule mua ma hope o ka hoʻokomo ʻana, ua ʻike ʻo Li Ming i ke kuni iki a me ka luhi, nā hopena pōkole maʻamau i ka lāʻau lapaʻau CAR-T cell. ʻElua pule ma hope mai, ua hoʻomaikaʻi nui ʻia kona ptosis a me ka paʻakikī i ka ʻōlelo ʻana, a ua hoʻomaka kona ikaika e hoʻi mai.

2. Hoʻomaikaʻi Waena Kau: ʻElua mahina ma hope mai, ua emi nui nā hōʻailona o Li Ming. Ua hiki iā ia ke hoʻi hou i nā hana aʻo maʻamau, ua holomua kāna hana, a ua hōʻike ʻia kona ʻano ola i ka hoʻomaikaʻi nui ʻana.

3. Nā hopena lōʻihi: ʻEkolu mahina ma hope o ka mālama ʻana, ʻaʻole i hilinaʻi hou ʻo Li Ming i nā lāʻau lapaʻau ma mua. Ua hōʻike nā hoʻokolohua ma hope aku ua maikaʻi ke kūlana o kāna ʻōnaehana pale, me ka ʻike ʻole ʻia o nā hopena ʻino.

Ma o ka lāʻau lapaʻau CAR-T cell, ua kāohi nui ʻia ka myasthenia gravis o Li Ming. "Mahalo nui wau no ka lāʻau lapaʻau CAR-T a me ka hui lapaʻau i hoʻolaʻa ʻia no kā lākou mau hana," wahi a Li Ming me ka waimaka, e lulu lima ana i ke kauka i ka wā i hoʻokuʻu ʻia ai.