Tsarin Lupus Erythematosus (SLE)-04

Tun tana 'yar shekara 7, Yaoyao (wani sunan barkwanci) ta fara lura da bayyanar kuraje ja a fuskarta, wanda a hankali ya bazu a jikinta. Baya ga waɗannan alamomin, ta fuskanci ciwon baki mai yawan faruwa da kuma ciwon gaɓoɓi masu ɗorewa, wanda hakan ya sa iyalinta suka nemi taimakon likita. Bayan an yi mata cikakken bincike a asibiti, an gano cewa Yaoyao yana da cutar lupus erythematosus (SLE), wata cuta da ke shafar garkuwar jiki wadda aka san ta da rikitarwa da kuma rashin tabbas.

Cikin shekaru uku, Yaoyao ta yi jinya mai tsanani da kuma bin diddigin marasa lafiya akai-akai a asibiti. Duk da karuwar yawan magungunan da ake sha, yanayinta bai nuna wani ci gaba ba. A lokaci guda kuma, furotin da ke cikinta, wanda ke nuna cewa koda tana cikin SLE, ya ci gaba da karuwa, wanda hakan ya haifar da damuwa da damuwa ga 'yan uwanta.

Ta hanyar tura wata aminiyarta, an gabatar da Yaoyao ga BIOOCUS Medical Group, inda ta shiga wani gwaji mai ban mamaki na asibiti na CAR-T. Bayan wani tsari mai tsauri na tantancewa, an karɓe ta a gwajin a ranar 8 ga Afrilu. Daga baya, a ranar 22 ga Afrilu, an yi mata gwajin ƙwayoyin halitta, kuma a ranar 12 ga Mayu, an haɗa mata ƙwayoyin halitta da aka yi wa magani da CAR-T. An sallame ta daga asibiti a ranar 27 ga Mayu, wanda hakan ya nuna muhimmiyar rawa a tafiyarta ta neman magani.

A cikin wata na farko da ta yi bincike a kan cutar, kwararrun likitoci sun lura da ci gaba mai yawa, musamman raguwar furotin a cikin fitsari. A ziyarar da ta kai, kurajen fatarta sun kusa ɓacewa, tare da ƙaramin kuraje kawai a kuncinta na dama. Abin da ya fi muhimmanci shi ne, furotin a cikin fitsarinta ya warke gaba ɗaya, kuma sakamakon SLE Disease Activity Index (SLEDAI-2K) ya nuna cewa tana da ɗan ƙaramin yanayin rashin lafiya, ƙasa da 2.

Saboda ƙarfin da Yaoyao ta samu daga ingancin maganin ƙwayoyin cuta na CAR-T, a hankali ta rage magungunanta a ƙarƙashin kulawar likita mai kyau. Abin mamaki, ta shafe sama da watanni huɗu ba tare da magani ba, wanda hakan ya tabbatar da ci gaba da samun sauƙi ta hanyar wannan sabuwar hanyar magani.

Tafiyar Yaoyao ta nuna ƙarfin da maganin CAR-T ke da shi wajen magance matsalolin da suka shafi garkuwar jiki kamar SLE, wanda hakan ke ba da bege da sakamako mai ma'ana inda magungunan gargajiya za su iya gazawa. Kwarewarta ta zama wata alama ta fata ga marasa lafiya da iyalai da ke fuskantar irin waɗannan ƙalubale, tana nuna makomar maganin da aka keɓance a fannin kula da cututtukan da ke shafar garkuwar jiki.