Lupus Erythematosus Pūnaha (SLE)-04

I te whitu o ōna tau, ka tīmata a Yaoyao (he ingoa huna) ki te kite i te putanga mai o ngā ponana whero i tōna mata, ka horapa haere puta noa i tōna tinana. Haunga ēnei tohu, i pāngia ia e ngā mate pukupuku waha me ngā mamae hononga tonu, ā, ka rapu awhina hauora tōna whānau. Whai muri i ngā whakamātautau hōhipera, i kitea a Yaoyao he mate pūnaha lupus erythematosus (SLE), he mate pūnaha ārai mate e mōhiotia ana mō tōna āhua uaua me te kore e taea te matapae.

I roto i ngā tau e toru, i whiwhi a Yaoyao i te maimoatanga nui me ngā tirotiro auau i te hōhipera. Ahakoa te pikinga o ngā horopeta rongoā kua tata ki tōna taumata teitei, kāore i tino pai ake tōna āhua. I taua wā anō, i piki haere tonu tana pūmua i roto i te mimi, he tohu mō te pānga o te whatukuhu ki te SLE, ā, ka puta te pouri me te āwangawanga i waenga i ōna mema whānau.

Nā te tukunga mai a tētahi hoa pono, i whakaurua a Yaoyao ki te Rōpū Hauora BIOOCUS, ā, i reira ia i uru atu ai ki tētahi whakamātautau haumanu hou a CAR-T. Whai muri i tētahi tukanga aromatawai pakari, i whakaaetia ia ki te whakamātautau i te 8 o Paenga-whāwhā. Nō muri mai, i te 22 o Paenga-whāwhā, i kohia ia i roto i te pūtau, ā, i te 12 o Mei, i whiwhi ia i te werohanga o ngā pūtau i rongoatia ki te CAR-T. Ko tana putanga angitu i te 27 o Mei he wā nui i roto i tana haerenga maimoatanga.

I tana marama tuatahi o te tirotiro, i kite ngā tohunga hauora i te ahunga whakamua nui, inā koa te hekenga o te pūmua mimi. I ngā haerenga i muri mai, kua tata ngaro ngā ponana kiri, me te toe noa he ponana iti i tōna paparinga matau. Ko te mea nui, kua memeha katoa tana pūmua mimi, ā, ko tana kaute SLE Disease Activity Index (SLEDAI-2K) i tohu he āhua mate ngawari, iti iho i te 2.

I te whakamanahia e te whai huatanga o te rongoā pūtau CAR-T, ka āta whakaitihia e Yaoyao ana rongoā i raro i te tirotiro a te rata. He mea whakamiharo, kua neke atu i te whā marama ia e kore ana e kai rongoā, e whakaatu ana i te whakaoranga pumau i tutukihia mā tēnei huarahi maimoatanga auaha.

E whakaatu ana te haerenga a Yaoyao i te kaha whakarerekētanga o te rongoā CAR-T ki te whakahaere i ngā mate pūnaha ārai mate kino pēnei i te SLE, e tuku ana i te tumanako me ngā hua e kitea ana i ngā wā ka kore e angitu ngā maimoatanga tuku iho. Ko tana wheako he tohu o te hihiri mō ngā tūroro me ngā whānau e whakatere ana i ngā wero rite, e whakaatu ana i te heke mai whai hua o te rongoā whaiaro i roto i te whakahaere i ngā mate pūnaha ārai mate.