ʻO ka maʻi leukemia lymphoblastic koʻikoʻi (T-ALL)-09

Ua loaʻa i kahi haumāna kulanui i kapa ʻia ʻo Mengmeng mai Yanjiao, Guizhou, kahi lāʻau lapaʻau kūpono ma BIOOCUS Medical Group.

ʻO Mengmeng, wahine, 21 makahiki, i hōʻea mai i kā mākou keʻena lapaʻau ma waho ma Iune 22, 2021, me ka luhi mau. Ua hōʻike ka hoʻāʻo koko maʻamau i ka WBC 479 × 10 ^ 9 / L. Ua hōʻoia nā hoʻokolohua iwi hou i ka leukemia lymphoblastic acute (T-cell subtype). Ua hana ʻo ia i ʻelua mau pōʻaiapuni o ka chemotherapy, akā ʻaʻole i pane ka leukemia, me ka MRD (minimal residual disease) ma 56.01%, a ua pili pū ʻo ia me ka leukemia o ka ʻōnaehana nerve waena.

Ma ʻAukake 13, ua hōʻiliʻili ʻia nā lymphocytes autologous a ua lawelawe ʻia ka chemotherapy. Ma ʻAukake 30, ua loaʻa iā Mengmeng ka hoʻokomo ʻana o nā cell CD7 CAR-T. ʻElua pule ma hope o ka hoʻokomo ʻana, ua hōʻike ka nānā ʻana o ka iwi iwi i ka hoʻomaha piha ʻana, ka maikaʻi ʻole o ka MRD, a me ka kaohi ʻana o ka leukemia o ke kikowaena nerve. Ua ʻike ʻo ia i kahi hopena cytokine release syndrome (CRS) papa 1 me ka ʻole o nā hopena maikaʻi ʻole o ke kikowaena nerve.