Acute Lymphoblastic Leukemia(T-ALL)-09

He akonga whare wananga ko Mengmeng te ingoa no Yanjiao, Guizhou, i whiwhi maimoatanga whai hua i te Rōpū Hauora BIOOCUS.

Ko Mengmeng, he wahine, 21 nga tau, i tae atu ki to maatau whare hauora i waho i te 22 o Hune, 2021, me te ngenge tonu. Ko nga whakamatautau toto i whakaatu i te WBC 479×10^9/L. Ko etahi atu whakamatautau i te hinu wheua i whakapumau i te kanisia lymphoblastic whakapeka (momo-waaroto T). E rua nga huringa o te whakamaarama haumanu, engari karekau tonu ia i te urupare, me te MRD (te iti o te mate toenga) i te 56.01%, a, i uru ano ia ki te reukemia o te punaha nerve.

I te 13 o Akuhata, ka kohia nga lymphocytes autologous, ka whakahaerehia te chemotherapy. I te 30 o Akuhata, ka whiwhi a Mengmeng i te whaowhia o te pūtau CD7 CAR-T. E rua wiki i muri mai i te whaowhia, ka kitea te whakamaaramatanga o te hinu wheua i te murunga katoa, te kino o te MRD, me te whakahaerenga o te reukemia o te punaha nerve matua. I pa ki a ia he tauhohenga mate cytokine release syndrome (CRS) kōeke 1 me te kore he tauhohenga kino o te punaha io matua.