ʻO ka maʻi Leukemia Lymphoblastic ʻoʻoleʻa (T-ALL)-08

ʻĪ maila ʻo Yesheng mai Fujian mai, "Inā wau i ʻike e pili ana iā CAR-T ma BIOOCUS Medical Group, inā ua hele mua wau."

I Kepakemapa 2017, ua loaʻa iā Yesheng nā ʻulaʻula maka, kahi i pālahalaha mālie a hui pū ʻia i loko o nā ʻāpana. I ka lā 28 o Pepeluali, 2018, ua hōʻoia ka nānā ʻana o ka iwi iwi i ka "acute T-cell lymphoblastic leukemia" ma hope o nā papa he nui o ka chemotherapy, me nā nānā koena maikaʻi ʻole. Ua hoʻōki ʻia nā lāʻau lapaʻau āpau i Iune 2019.

I Mei 2021, ua hōʻike ʻo Yesheng me nā puʻupuʻu ma ka ʻāpana waha-pharyngeal a me nā lymph node ʻāʻī i hoʻonui ʻia. Ua hōʻoia ka nānā hou ʻana o ka iwi iwi i ka hoʻi hou ʻana o ka leukemia. I ka lā 28 o Mei, ua hoʻoneʻe ʻia ʻo Yesheng i ka ʻOihana Hematology ʻElua no ke komo ʻana. Ma hope o nā hoʻokolokolo piha, ua hoʻoponopono hou ʻia ka maʻi i "acute leukemia (T/myeloid biphenotypic)."

ʻAʻole i hoʻoulu kekahi pōʻaiapuni o ka chemotherapy i ka hoʻomaha ʻana i loko o ka iwi iwi. Ma Iulai 27, ua loaʻa iā Yesheng ka hoʻokomo ʻana o ke kelepona CD7 CAR-T, a ukali ʻia e ka chemotherapy i hui pū ʻia me ka lāʻau lapaʻau kelepona CD7 CAR-T autologous. He ʻumikumamālima mau lā ma hope o ka hoʻokomo ʻana, ua hōʻike ka nānā ʻana o ka iwi iwi i ka maʻi koena maikaʻi ʻole, me kahi hopena cytokine release syndrome (CRS) papa 1 a ʻaʻohe hopena maikaʻi ʻole o ka ʻōnaehana nerve waena.