ʻO ka maʻi Leukemia Lymphoblastic ʻoʻoleʻa (T-ALL)-05

Hoʻomaha ʻia o kahi maʻi T-ALL i hoʻi hou me ka Leukemia ʻōnaehana nerve waena ma hope o ka lāʻau CAR-T

Pili kēia hihia i kahi keikikāne 16 makahiki mai ka Hikina ʻĀkau o Kina, nona ka huakaʻi me ka leukemia i piha i nā pilikia mai kona wā i ʻike ʻia ai he maʻi ia ma mua o hoʻokahi makahiki i hala.

Ma Nowemapa 8, 2020, ua kipa aku ʻo Dawei (he inoa kapakapa) i kahi haukapila kūloko ma muli o ka ʻoʻoleʻa o ka maka, ka ʻulaʻula, a me ka waha kekee. Ua ʻike ʻia ʻo ia me ka "acute lymphoblastic leukemia (ʻano T-cell)." Ma hope o hoʻokahi papa hana chemotherapy induction, ua maikaʻi ʻole ka MRD (minimal residual disease), a ukali ʻia e ka chemotherapy maʻamau. I loko o kēia wā, ʻaʻohe ʻano ʻē i hōʻike ʻia e ka puncture bone marrow, lumbar puncture, a me nā injections intrathecal.

Ma Mei 6, 2021, ua hana ʻia kahi puncture lumbar me ka injection intrathecal, a ua hōʻoia ka loiloi wai cerebrospinal (CSF) i ka "leukemia ʻōnaehana nerve waena." Ua ukali ʻia kēia e ʻelua mau papa o ka chemotherapy maʻamau. Ma Iune 1, ua hōʻike kahi puncture lumbar me ka loiloi CSF i nā cell immature. Ua lawelawe ʻia ʻekolu mau puncture lumbar hou me nā injections intrathecal, me ka hoʻāʻo CSF ​​hope loa e hōʻike ana ʻaʻohe cell tumor.

Ma Iulai 7, ua nalowale ka ʻike o Dawei ma kona maka ʻākau, a ua emi iho i ka ʻike ʻana i ka mālamalama wale nō. Ma hope o hoʻokahi papa hana chemotherapy ikaika, ua hoʻi hou ka ʻike o kona maka ʻākau i ka maʻamau.

Ma ʻAukake 5, ua hōʻino hou ka ʻike o kona maka ʻākau, a ua lilo i makapō loa, a ua lilo kona maka hema i mea pohihihi. Mai ʻAukake 10 a 13, ua hana ʻia ʻo ia i ka radiotherapy lolo holoʻokoʻa a me ke kaula spinal (TBI), ka mea i hoʻihoʻi i ka ʻike ma kona maka hema, akā ua noho makapō ka maka ʻākau. Ma ʻAukake 16, ua hōʻike kahi scan MRI o ka lolo i kahi hoʻomaikaʻi iki i ka mānoanoa o ke aʻalolo optic ʻākau a me ka chiasm, me ka hoʻonui ʻia ʻana i ʻike ʻia. ʻAʻohe hōʻailona ʻē aʻe a i ʻole nā ​​hoʻonui ʻana i loaʻa i loko o ka parenchyma o ka lolo.

I kēia manawa, ua hoʻomākaukau ka ʻohana no ka hoʻoili iwi iwi, e kali ana i kahi moe wale nō ma ka lumi hoʻoili. ʻO ka mea pōʻino, ua hōʻike nā hoʻokolohua maʻamau ma mua o ka hoʻoili ʻana i nā pilikia i hiki ʻole ai ke hoʻoili.